ChemicalBook >> CAS DataBase List >>2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile structure

CAS No.: 93413-76-4

Chemical Name:: 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile

Synonyms: forVenlafaxine;Venlafaxine Cyano;Venlafaxine Impurity 15;Venlafaxine Impurity 28;Venlafaxine Cyano Impurity;Intermediate of Venlafaxine;Venlafaxine Nitrile Impurity;1-[Cyano-(4-Methoxyphenyl)Meth;D,L-VENLAFAXINE, HYDROCHLORIDE int;4-Methoxy benzyl cyano cyclohexanol

CBNumber:: CB6476117

Molecular Formula:: C15H19NO2

Molecular Weight:: 245.32

MDL Number:: MFCD06658142

MOL File:: 93413-76-4.mol

MSDS File:: SDS

Last updated:2023-06-08 17:06:35

Request For Quotation

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Properties

Melting point	121-123°C
Boiling point	410.1±25.0 °C(Predicted)
Density	1.142±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	soluble in Methanol
form	powder to crystal
pka	13.80±0.20(Predicted)
color	White to Almost white
CAS DataBase Reference	93413-76-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H312+H332-H315-H319
Precautionary statements	P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501
HS Code	2926.90.4850

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	H1303	(1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile >98.0%(HPLC)(N)	93413-76-4	1g	$116	2023-06-20	Buy
TCI Chemical	H1303	(1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile >98.0%(HPLC)(N)	93413-76-4	5g	$349	2023-06-20	Buy
Biosynth Carbosynth	FC20603	1-[Cyano-(4-methoxyphenyl)methyl]cyclohexanol	93413-76-4	25mg	$254.5	2021-12-16	Buy
Biosynth Carbosynth	FC20603	1-[Cyano-(4-methoxyphenyl)methyl]cyclohexanol	93413-76-4	10mg	$139.8	2021-12-16	Buy
Biosynth Carbosynth	FC20603	1-[Cyano-(4-methoxyphenyl)methyl]cyclohexanol	93413-76-4	50mg	$462	2021-12-16	Buy

Product number	Packaging	Price	Buy
H1303	1g	$116	Buy
H1303	5g	$349	Buy
FC20603	25mg	$254.5	Buy
FC20603	10mg	$139.8	Buy
FC20603	50mg	$462	Buy

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Chemical Properties,Uses,Production

Synthesis

A mixture of p-methoxyphenylacetonitrile 36 (100 g, 0.68 mol), 10% aqueous NaOH solution (100 ml, 0.25 mol) and TBAHSO4 (5 g, 0.014 mol) was stirred at room temperature for 30 minutes. A dark red colour appeared. To this was added cyclohexanone 34 (67 g, 0.680 mol) in small portions at 0 ºC, with vigorous stirring, in such a way that temperature should not rise above 10 ºC. A white solid was formed within 30 minutes to one hour. The solid was crushed and the reaction mixture was further stirred vigorously at room temperature for one more hour. The solid was filtered, washed with water till neutral to pH paper and air-dried. Crystallization from ethyl acetatepetroleum ether (500:350, v/v) gave a bright white solid (161.66 g).

Chemical Properties

White Powder

Uses

An intermediate in the synthesis of N,O-Didesmethylvenlafaxine, a metabolite of Venlafaxine

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile synthesis

Synthesis of 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile from Cyclohexanone

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Preparation Products And Raw materials

Raw materials

Cyclohexanol Anisonitrile 4-Methoxybenzyl cyanide Cyclohexanone

Preparation Products

N,N-dimethyl-4-methoxyphenylethylamine D,L N-Desmethylvenlafaxine

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Suppliers

Global( 251)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2967	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Hangzhou FandaChem Co.,Ltd.	55
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei Jusheng Technology Co.,Ltd.	58
Jinan Finer Chemical Co., Ltd	58
Standardpharm Co. Ltd.	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58

View Lastest Price from 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2022-09-14	2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile 93413-76-4	US $0.00-0.00 / KG	1KG	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
	2019-07-06	1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol 93413-76-4	US $8.80 / KG	1KG	97%-99%	100kg	Career Henan Chemical Co

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile
93413-76-4
US $0.00-0.00 / KG
98%
Henan Aochuang Chemical Co.,Ltd.

1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol
93413-76-4
US $8.80 / KG
97%-99%
Career Henan Chemical Co

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Spectrum

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile(93413-76-4)¹HNMR 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile(93413-76-4)¹³CNMR

93413-76-4(2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile)Related Search:

4-Methoxyphenylacetic acid (3,4-Dimethoxyphenyl)acetonitrile Methanol Cyclohexanol (3-Methoxyphenyl)acetonitrile

Methyl acrylate Acetonitrile Benzeneacetonitrile Vinyltrimethoxysilane Methylparaben

Basic Violet 1 Diphenylacetonitrile 4-Methoxybenzyl cyanide Kresoxim-methyl Paraquat dichloride

4-BROMO-2,2-DIPHENYLBUTYRONITRILE rac N,N-DidesMethyl-N-(4-hydroxyphenethyl)-O-desMethyl Venlafaxine (2RS)-2-Cyclohexyl-2-(4-Methoxyphenyl)-N,NdiMethylethanaMineHydrochloride

1of4

alpha-(1-Hydroxycyclohexyl)-4-methoxybenzeneacetonitrile 1-(Hydroxycyclohexyl)-(4-Methoxyphenly)Acetonitrlle 1-[(1-CYANO)-1-(4-METHOXYPHENYL)METHYL]CYCLODEXANOL 1-[Cyno-(4-Methoxyphenyl)Methyl]Cyclohexanol(Vf1) 1-HydroxyCyclohexyl-4-MethoxyPhenylAcetonitrile(ForVenlafaxineHcl) forVenlafaxine 1-(cyclohexanol)-(4methoxyphenyl)acetonitrile Intermediate of Venlafaxine 1-[Cyano-(4-Methoxyphenyl)Meth 1-(hydroxycyclohexyl)-(4-methoxyphenyl)acetonitrile (intermediate of venlafaxine) 1-hydroxy cyclohexyl-4-methoxy phenyl acetonitrile (intermediate of venlafaxine hcl) 1-[CYANO-(4-METHOXYPHENYL)METHYL]CYCLOHEXANOL[FOR VENLAFAXINE HCL] 4-Methoxy benzyl cyano cyclohexanol 1-(p-Methoxyphenyl-cyano)-methylcyclohexanol α-(1-Hydroxycyclohexyl)-4-Methoxy-benzeneacetonitrile α-(p-Methoxyphenyl)-α-(1-hydroxycyclohexyl)acetonitrile Venlafaxine Hydroxy Nitrile Impurity Venlafaxine Cyano Impurity 1-[(1-CYANO)-1-(4-METHOXYPHENYL)METHYL] CYCLOHEXANOL 1-[CYANO-(P-METHOXYPHENYL)METHYL]CYCLOHEXANOL 1-(CYANO-(4-METHOXY PHENYL) METHYL) CYCLOHEXANOL Venlafaxine hydroxynitrile impurities Venlafaxine Nitrile Impurity Venlafaxine Impurity 3 (Venlafaxine Hydroxy Nitrile Impurity) D,L-VENLAFAXINE, HYDROCHLORIDE int 3-(1-hydroxycyclohexyl)-2-(4-methoxyphenyl)propanenitrile Venlafaxine Impurity 15 (1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile> Benzeneacetonitrile, α-(1-hydroxycyclohexyl)-4-methoxy- 1-(HYDROXYCYCLOHEXY)-(4-METHOXYPHENLY)ACETONITRLLE 1- [Cyano (P- Methoxyphenyl) Methyl] Cyclohexanol: VNF Stage-I Venlafaxine Impurity 28 2-(1-Hydroxycyclohexyl)-2-(4-methoxypheny)acetonitrile 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile 1-[Cyano-(4-methoxyphenyl)methyl] cyclohexanol (VENLA-I) Benzeneacetonitrile, α-(1-hydroxycyclohexyl)-4-methoxy- Venlafaxine Cyano (1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile, ≥ 98.0% 93413-76-4 C15H19O2N Intermediates & Fine Chemicals Pharmaceuticals Medicine intermediate Nitriles API intermediates (intermediate of venlafaxine) (intermediate of venlafaxine hcl)