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Ethyl hydrogen malonate

Ethyl hydrogen malonate structure

CAS No.: 1071-46-1

Chemical Name:: Ethyl hydrogen malonate

Synonyms: MONOETHYL MALONATE;Monoethyl malonic acid;3-ethoxy-3-oxopropanoate;3-ethoxy-3-oxapropanoic acid;3-ethoxy-3-oxo-propanoic acid;en maL;BROP-001;hydrogen maL;Ethyl hydrogen malon;Malonic acid 1-ethyl

CBNumber:: CB6477583

Molecular Formula:: C5H8O4

Molecular Weight:: 132.11

MDL Number:: MFCD00020490

MOL File:: 1071-46-1.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:08

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Ethyl hydrogen malonate Properties

Melting point	-13°C(lit.)
Boiling point	106.5 °C/3 mmHg (lit.)
Density	1.119 g/mL at 25 °C (lit.)
refractive index	n20/D 1.435(lit.)
Flash point	>230 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Sparingly)
form	Liquid
pka	pK1:3.55 (25°C)
color	Pale yellow
Water Solubility	Miscible with water, chloroform and other solvents.
BRN	1758845
InChIKey	HGINADPHJQTSKN-UHFFFAOYSA-N
CAS DataBase Reference	1071-46-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

HS Code

29171900

NFPA 704

	1
2		0

Ethyl hydrogen malonate price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	445088	mono-Ethyl malonate	1071-46-1	5g	$58.1	2024-03-01	Buy
TCI Chemical	M2700	Monoethyl Malonate >98.0%(T)	1071-46-1	5g	$35	2024-03-01	Buy
TCI Chemical	M2700	Monoethyl Malonate >98.0%(T)	1071-46-1	25g	$105	2024-03-01	Buy
Alfa Aesar	044692	Ethyl hydrogen malonate, 90+%	1071-46-1	5g	$31.65	2024-03-01	Buy
Alfa Aesar	044692	Ethyl hydrogen malonate, 90+%	1071-46-1	25g	$102.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
445088	5g	$58.1	Buy
M2700	5g	$35	Buy
M2700	25g	$105	Buy
044692	5g	$31.65	Buy
044692	25g	$102.65	Buy

Ethyl hydrogen malonate Chemical Properties,Uses,Production

Chemical Properties

Yellow liquid

Uses

Ethyl hydrogen malonate is used as a reactant for the preparation of tetramic acids through Dieckmann ring closure and organocatalytic decarboxylative Doebner-Knoevenagel reactions. It is involved in the acylation reactions and Knoevenagel condensation with aldehydes. It is also used in the preparation of gamma-lactones from olefins by intermolecular carbolactonization in presence of Mn(III) acetate as a catalyst.

Uses

Ethyl Hydrogen Malonate has been shown to impair brain mitochondrial succinate and malate transport. It is also found in the extract of Hericum erinaceus mushroom which shows antitumor effects in tumo r-bearing mice.

Definition

ChEBI: Monoethyl malonic acid is a dicarboxylic acid.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 4, p. 417, 1963
Tetrahedron Letters, 26, p. 1411, 1985 DOI: 10.1016/S0040-4039(00)99058-0

Ethyl hydrogen malonate synthesis

Synthesis of Ethyl hydrogen malonate from Ethyl potassium malonate

Ethyl hydrogen malonate Preparation Products And Raw materials

Raw materials

Preparation Products

RARECHEM AL BI 0736 6-BENZYL-2-THIOURACIL Amlexanox 4-Hydroxy-3,5-dimethoxycinnamic acid TERT-BUTYL ETHYL MALONATE

Ethyl potassium malonate Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate 3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER ETHYL 3-METHOXYPHENYLACETATE Ethyl isobutyrylacetate

TERT-BUTYL 3-(ETHOXYCARBONYL)-2-OXOPROPYLCARBAMATE ETHYL (2-METHOXYBENZOYL)ACETATE 3-(3,4-DICHLORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER ETHYL 2-(2-CHLOROPHENYL)ACETATE 3-(4-BROMO-2-FLUORO-3-METHOXY-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER

ETHYL 3-(3-CHLORO-2,4,5-TRIFLUOROPHENYL)-3-OXOPROPANOATE

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Ethyl hydrogen malonate Suppliers

Global( 334)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88299272	info@edengenechem.com	China	2169	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Accela ChemBio Inc.	58
Xiamen AmoyChem Co., Ltd	58
Changzhou Ditong Chemical Co.,Ltd	58
Chongqing Chemdad Co., Ltd	58

View Lastest Price from Ethyl hydrogen malonate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-06-26	Monoethyl malonic acid 1071-46-1	US $300.00 / kg	10kg	99%	500kg/month	Hebei Mingeng Biotechnology Co., Ltd
2022-09-30	Ethyl hydrogen malonate 1071-46-1	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2021-07-13	Ethyl hydrogen malonate 1071-46-1	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

Monoethyl malonic acid
1071-46-1
US $300.00 / kg
99%
Hebei Mingeng Biotechnology Co., Ltd

Ethyl hydrogen malonate
1071-46-1
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

Ethyl hydrogen malonate
1071-46-1
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Ethyl hydrogen malonate Spectrum

Ethyl hydrogen malonate(1071-46-1)IR

1071-46-1(Ethyl hydrogen malonate)Related Search:

Diethyl ethylmalonate 2-Ethoxyethanol Ethanol Ethylparaben Hydrogen

Ethyl potassium malonate Ethyl Succinyl Chloride Diethyl malonate Dimethyl malonate Diethyl chloromalonate

Potassium 3-methoxy-3-oxopropanoate ISOXADIFEN-ETHYL Trinexapac-ethyl MONO-ETHYL SUCCINATE Ethyl acetate

2-AMINODIETHYLMALONATE Ethyl malonyl chloride Diethyl methylmalonate

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ETHYL HYDROGEN MALONATE Ethyl hydrogen malonate, 90+% Ethoxycarbonylacetic acid Malonic acid 1-ethyl Malonic acid 1-ethyl ester Malonic acid hydrogen 1-ethyl ester malonic acid half ethyl ester 3-ethoxy-3-keto-propionic acid Ethyl hydrogen malon Monoethyl hydrogen malonate Propanedioic acid, 1-ethyl ester Ethyl hydrogen malonate, technical, 90% BROP-001 en maL Cabozantinib impurity 59 Monoethyl Malonate > hydrogen maL Valproic Acid Impurity 34 MONOETHYL MALONATE 3-ethoxy-3-oxapropanoic acid Monoethyl malonic acid 3-ethoxy-3-oxo-propanoic acid 3-ethoxy-3-oxopropanoate Ethyl Hydrogen Malanoate(MEM) ETHYL HYDROGENMALONATE 3-ethoxy-3-oxo-propanoic acid mono-Ethyl malonate 1071-46-1 HO2CCH2CO2CH2CH3 HO2CCH2CO2C2H5 C5H8O4 Organic Building Blocks Esters CARBOXYLIC ACID Building Blocks C2 to C5 Carbonyl Compounds Thiophenes ,Thiazolines/Thiazolidines Small molecule API intermediates C2 to C5 Carbonyl Compounds Esters bc0001