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Dolutegravir 2-Desfluoro Impurity

Dolutegravir 2-Desfluoro Impurity structure

CAS No.: 1863916-88-4

Chemical Name:: Dolutegravir 2-Desfluoro Impurity

Synonyms: 4-Fluoro Dolutegravir;Dolutegravir Impurity G;Dolutegravir Impurity 50;Dolutegravir Impurity 47;Dolutegravir 4-Fluoro Impurity;Dolutegravir 2-Desfluoro Impurity;(4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity;Dolutegravir impurity 4/Defluoro Dolutegravir/(4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

CBNumber:: CB64796145

Molecular Formula:: C20H20FN3O5

Molecular Weight:: 401.39

MDL Number:

MOL File:: 1863916-88-4.mol

Last updated:2023-07-12 17:02:14

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Dolutegravir 2-Desfluoro Impurity Properties

Boiling point	675.7±55.0 °C(Predicted)
Density	1.49±0.1 g/cm3(Predicted)
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
form	Solid
pka	4.50±1.00(Predicted)
color	Off-White to Light Brown
FDA UNII	CT8QT9HZN8

Dolutegravir 2-Desfluoro Impurity price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	D228715	DefluoroDolutegravir	1863916-88-4	10mg	$1080	2021-12-16	Buy

Product number	Packaging	Price	Buy
D228715	10mg	$1080	Buy

Dolutegravir 2-Desfluoro Impurity Chemical Properties,Uses,Production

Uses

Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir 2-Desfluoro Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

Dolutegravir 2-Desfluoro Impurity Suppliers

Global( 31)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CR Corporation Lomited		fred.wen@crcorporation.cn	CHINA	12069	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	+8613627253706	sale@hdimpurity.com	China	1490	58
Shenzhen Roark Pharma-Tec Co., Ltd.	13128912434	2880126944@qq.com	China	2580	58
Beijing Comparison Pharmaceutical Technology Co., Ltd	010-52878169 15701683040	sales@bjcomparison.com	China	4663	58
ChemStrong Scientific Co.,Ltd	0755-66853366 13670046396	sales@chem-strong.com	China	17982	56
Shanghai CR Corporation Limited	4006653949	fred.wen@crcorporation.cn	China	10108	58
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	020-89854820	sales@jzpharma.cn	China	1072	58
Shenzhen Jianyi Biotechnology Co., Ltd	0755-84826604	3001783715@qq.com	CHINA	2898	58

Supplier	Advantage
CR Corporation Lomited	58
sgtlifesciences pvt ltd	58
China National Standard Pharmaceutical Corporation Limited	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	58
Shenzhen Roark Pharma-Tec Co., Ltd.	58
Beijing Comparison Pharmaceutical Technology Co., Ltd	58
ChemStrong Scientific Co.,Ltd	56
Shanghai CR Corporation Limited	58
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	58
Shenzhen Jianyi Biotechnology Co., Ltd	58

1863916-88-4(Dolutegravir 2-Desfluoro Impurity)Related Search:

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2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity Dolutegravir impurity 4/Defluoro Dolutegravir/(4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide Dolutegravir Impurity G Dolutegravir 2-Desfluoro Impurity 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)- (4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide Dolutegravir Impurity 47 Dolutegravir Impurity 50 4-Fluoro Dolutegravir Dolutegravir 4-Fluoro Impurity 1863916-88-4