BRD2 Inhibitor II, BIC1 - Calbiochem

BRD2 Inhibitor II, BIC1 - Calbiochem structure

CAS No.

Chemical Name:: BRD2 Inhibitor II, BIC1 - Calbiochem

Synonyms: BRD2 Inhibitor II, BIC1 - Calbiochem

CBNumber:: CB64816928

Molecular Formula:

Molecular Weight:: 0

MDL Number:

MOL File:: Mol file

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BRD2 Inhibitor II, BIC1 - Calbiochem price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	203830	BRD2 Inhibitor II, BIC1 - Calbiochem The BRD2 Inhibitor II, BIC1 controls the biological activity of BRD2.		10mg	$130	2024-03-01	Buy

Product number	Packaging	Price	Buy
203830	10mg	$130	Buy

BRD2 Inhibitor II, BIC1 - Calbiochem Chemical Properties,Uses,Production

General Description

A cell-permeable benzimidazolyl-benzimidazolothione that targets the BD1 domain of the BET family member BRD2 (K_d = 28 μM), making it inaccessible for acetylated H4K12 (histone H4 Lys12) binding. Shown to effectively inhibit TSA- (Cat. No. 647925; 1 h 1 μM) induced BRD2 BD1-H4K12 association in COS7 cells (100% inhibition by 60 μM BIC1) and greatly suppress active Ras-induced SV40 promoter transcription activity in HeLa cells (70% inhibition by 5 μM BIC1), while being much less effective against BRDT BD1 binding to acetylated H4K5/K8.

BRD2 Inhibitor II, BIC1 - Calbiochem Preparation Products And Raw materials

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Preparation Products

BRD2 Inhibitor II, BIC1 - Calbiochem Suppliers

Global( 2)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80

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Sigma-Aldrich	80

BRD2 Inhibitor II, BIC1 - Calbiochem