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InSolution PARP Inhibitor VIII, PJ34 - Calbiochem

InSolution PARP Inhibitor VIII, PJ34 - Calbiochem Structure
InSolution PARP Inhibitor VIII, PJ34 - Calbiochem structure
CAS No.
Chemical Name:
InSolution PARP Inhibitor VIII, PJ34 - Calbiochem
Synonyms
InSolution PARP Inhibitor VIII, PJ34 - Calbiochem
CBNumber:
CB64817374
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
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InSolution PARP Inhibitor VIII, PJ34 - Calbiochem price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 528151 InSolution PARP Inhibitor VIII, PJ34 - Calbiochem 2mg $154 2023-06-20 Buy
Product number Packaging Price Buy
528151 2mg $154 Buy

InSolution PARP Inhibitor VIII, PJ34 - Calbiochem Chemical Properties,Uses,Production

General Description

A water-soluble phenanthridinone derivative that acts as a potent anti-inflammatory agent and a reversible inhibitor of poly(ADP-ribose) polymerase (PARP; EC50 = 20 nM). Shown to be about 10,000-fold more potent than the prototypical PARP inhibitor, 3-Aminobenzamide (Cat. No. 165350) (EC50 = 200 μM). Suppresses neutrophil infiltration and nitric oxide production in peritonitis. Does not act as an antioxidant even at higher concentrations (1 μM to 10 μM). PJ34 inhibits peroxynitrite-induced cell necrosis with an (EC50 = 20 nM). Exhibits neuroprotective effects in in vivo and in vitro models of stroke. The solid form of this compound (Cat. No. 528150) is also available.

Biochem/physiol Actions

Cell permeable: yes

InSolution PARP Inhibitor VIII, PJ34 - Calbiochem Preparation Products And Raw materials

Raw materials

Preparation Products

InSolution PARP Inhibitor VIII, PJ34 - Calbiochem Suppliers

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Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
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InSolution PARP Inhibitor VIII, PJ34 - Calbiochem