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AC-DEVD-CHO

AC-DEVD-CHO structure

CAS No.: 169332-60-9

Chemical Name:: AC-DEVD-CHO

Synonyms: MF 191;AC-DEVD-CHO;AC-DEVD-ALDEHYDE;AC-DEVD-CHO?, >98%;CASPASE-3 INHIBITOR;ACETYL-DEVD-ALDEHYDE;Ac-Asp-Glu-Val-Asp-H;CASPASE-3 INHIBITOR I;AC-DEVD-CHO USP/EP/BP;AcDEVDCHO,Ac DEVD CHO

CBNumber:: CB6488321

Molecular Formula:: C20H30N4O11

Molecular Weight:: 502.47

MDL Number:: MFCD00671412

MOL File:: 169332-60-9.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:19

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AC-DEVD-CHO Properties

Boiling point	1021.1±65.0 °C(Predicted)
Density	1.374±0.06 g/cm3(Predicted)
RTECS	EK7643000
storage temp.	-20°C
solubility	H₂O: 1 mg/mL
form	powder
pka	4.19±0.10(Predicted)
color	white
Sensitive	Moisture Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
WGK Germany	3

AC-DEVD-CHO price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	235420	Caspase-3 Inhibitor I	169332-60-9	1mg	$113	2024-03-01	Buy
Sigma-Aldrich	235420	Caspase-3 Inhibitor I	169332-60-9	5mg	$475	2024-03-01	Buy
Alfa Aesar	J65204	N-Acetyl-Asp-Glu-Val-Asp-al	169332-60-9	5mg	$401	2023-06-20	Buy
Alfa Aesar	J65204	N-Acetyl-Asp-Glu-Val-Asp-al	169332-60-9	1mg	$101	2021-12-16	Buy
Sigma-Aldrich	A0835	N-Acetyl-Asp-Glu-Val-Asp-al ≥95%, powder	169332-60-9	1mg	$161	2024-03-01	Buy

Product number	Packaging	Price	Buy
235420	1mg	$113	Buy
235420	5mg	$475	Buy
J65204	5mg	$401	Buy
J65204	1mg	$101	Buy
A0835	1mg	$161	Buy

AC-DEVD-CHO Chemical Properties,Uses,Production

Uses

Reversible inhibitor of interleukin-1beta converting enzyme (ICE); also inhibits caspase-3 cleavage of poly(ADP-ribose) polymerase

Uses

N-Acetyl-Asp-Glu-Val-Asp-al has been used as a caspase inhibitor in muscle samples, smooth muscle cells and Jurkat T-cells.

Definition

ChEBI: A tetrapeptide consisting of two L-aspartic acid residues, an L-glutamyl residue and an L-valine residue with an acetyl group at the N-terminal and with the C-terminal carboxy group reduced to an aldehyde. It is an inhibitor of caspase-3/7.

General Description

N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) is a tetrapeptide with N-terminal acetylation and C-terminal aldehyde conjugation.

Biochem/physiol Actions

N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) aids in the recovery of stunned myocardium by its caspase inhibition functionality.

AC-DEVD-CHO Preparation Products And Raw materials

Raw materials

Preparation Products

AC-DEVD-CHO Suppliers

Global( 72)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29220	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Zhejiang Hangyu API Co., Ltd	+8617531972939	anna@api-made.com	China	2944	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
DONBOO AMINO ACID COMPANY	+8613063595538	donboo@donboo.com	China	9365	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	94838	76

Supplier	Advantage
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei Jusheng Technology Co.,Ltd.	58
Dideu Industries Group Limited	58
Nextpeptide Inc	58
InvivoChem	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Zhejiang Hangyu API Co., Ltd	58
Aladdin Scientific	58
DONBOO AMINO ACID COMPANY	58
J & K SCIENTIFIC LTD.	76

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N-ACETYL-L-ALPHA-ASPARTYL-L-ALPHA-GLUTAMYL-N-(2-CARBOXY-1-FORMYLETHYL)-L VALINAMIDE N-AC-ASP-GLU-VAL-ASP-CHO N-ACETYL-ASP-GLU-VAL-ASP-AL N-ACETYL-ASP-GLU-VAL-ASP-CHO (ALDEHYDE) CPP32/APOPAIN INHIBITOR CASPASE-3 INHIBITOR I CASPASE-3 INHIBITOR (ALDEHYDE) ACETYL-DEVD-ALDEHYDE ACETYL-L-ASPARTYL-L-GLUTAMYL-L-VALYL-L-ASPART-1-AL ACETYL-ASP-GLU-VAL-ASP-ALDEHYDE AC-DEVD-CHO AC-DEVD-ALDEHYDE AC-ASP-GLU-VAL-ASP-ALDEHYDE AC-ASP-GLU-VAL-ASP-ALDEHYDE (PSEUDO ACID) AC-ASP-GLU-VAL-ASP-H (ALDEHYDE) AC-ASP-GLU-VAL-ASP-CHO Acetyl-aspartyl-glutamyl-valyl-aspartal CASPASE 3 (APOPAIN) INHIBITOR 1 MF 191 N-acetyl-Asp-Glu-Val-Asp-Ala (4S,7S,10S,13S)-7-(2-carboxyethyl)-4-(carboxyMethyl)-13-forMyl-10-isopropyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid Ac-Asp-Glu-Val-Asp-H CASPASE-3 INHIBITOR Ac-DEVD-CHO,N-Acetyl-Asp-Glu-Val-Asp-al, >98% AC-DEVD-CHO?, >98% Caspase-3 Inhibitor I - CAS 169332-60-9 - Calbiochem CASPASE-3 INHIBITOR I;N-AC-ASP-GLU-VAL-ASP-CHO;ACETYL-ASPARTYL-GLUTAMYL-VALYL-ASPARTAL L-Valinamide, N-acetyl-L-α-aspartyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]- N-Acetyl-Asp-Glu-Val-Asp-al >=95%, powder AC-DEVD-CHO USP/EP/BP Ac-DEVD-CHO，N-Acetyl-Asp-Glu-Val-Asp-al Caspase 3 Inhibitor I,Caspase3 Inhibitor I AcDEVDCHO,Ac DEVD CHO 169332-60-9 Caspase 10 Caspases Cell Biology Cell Signaling and Neuroscience Apoptosis and Cell Cycle BioChemical Inhibitors peptides Caspase 10 Caspase 3 Caspase 7 Caspase 8 Caspase Inhibitors Caspase Inhibitors and Substrates Peptides and Proteins Peptides for Cell Biology Protease Inhibitor Specificity Index Protease Inhibitors A to C A-AM Aldehydes and Substrates Apoptosis and Cell Cycle Apoptosis Enzymes