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RS 102895

CAS No.
300815-41-2
Chemical Name:
RS 102895
Synonyms
1'-(4-(trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one;RS 102895 HYDROCHLORIDE;CC chemokine receptor,CCR,Inhibitor,RS102895,inhibit,RS-102895,RS 102895;1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-spiro[4h-3,1-benzoxazine-4,4'-peperidin]-2(1h)-one;Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-;1'-(4-(TrifluoroMethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride;1'-[2-[4-(trifluoromethyl)phenyl]ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one,hydrochloride;1'-[2-[4-(TRIFLUOROMETHYL)PHENYL]ETHYL]-SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE HYDROCHLORIDE
CBNumber:
CB6504368
Molecular Formula:
C21H21F3N2O2
Molecular Weight:
390.4
MDL Number:
MFCD05865241
MOL File:
300815-41-2.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:10

RS 102895 Properties

Boiling point 446.1±45.0 °C(Predicted)
Density 1.33±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. Desiccate at RT
solubility DMSO: 18 mg/mL, clear, colorless
form powder
pka 13.46±0.20(Predicted)
color white

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

RS 102895 price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R1903 RS 102895 hydrochloride ≥98% (HPLC), powder 300815-41-2 5mg $241 2024-03-01 Buy
Tocris 2089 RS 102895 hydrochloride ≥99%(HPLC) 300815-41-2 10 $162 2021-12-16 Buy
Tocris 2089 RS 102895 hydrochloride ≥99%(HPLC) 300815-41-2 50 $682 2021-12-16 Buy
Usbiological 256510 RS 102895 hydrochloride 300815-41-2 10mg $403 2021-12-16 Buy
American Custom Chemicals Corporation API0008334 RS 102895 HYDROCHLORIDE 95.00% 300815-41-2 10MG $345.45 2021-12-16 Buy
Product number Packaging Price Buy
R1903 5mg $241 Buy
2089 10 $162 Buy
2089 50 $682 Buy
256510 10mg $403 Buy
API0008334 10MG $345.45 Buy

RS 102895 Chemical Properties,Uses,Production

Uses

RS 102895 is a CCR2-selective chemokine receptor inhibitor.

Biological Activity

CCR2-selective chemokine receptor antagonist (IC 50 values are 0.36 and 17.8 μ M for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Blocks MCP-1-stimulated calcium influx and chemotaxis with IC 50 values of 32 nM and 1.7 μ M respectively. Also inhibits α 1A , α 1D and 5-HT 1A receptors.

RS 102895 Preparation Products And Raw materials

Raw materials

Preparation Products

RS 102895 Suppliers

Global( 95)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai UCHEM Inc.
+862156762820 +86-13564624040 sales@myuchem.com China 6711 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894 shawn@hirisunpharm.com CHINA 9923 58
Henan Aochuang Chemical Co.,Ltd.
+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9425 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42057 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131981 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2923 55
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
VDM Biochemicals 0330-2528181 sales@vdmbio.com United States 510 64

View Lastest Price from RS 102895 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
RS 102895 pictures 2022-09-08 RS 102895
300815-41-2
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
  • RS 102895 pictures
  • RS 102895
    300815-41-2
  • US $0.00-0.00 / kg
  • 98%
  • Henan Aochuang Chemical Co.,Ltd.
1'-(4-(TrifluoroMethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride RS 102895 HYDROCHLORIDE 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-spiro[4h-3,1-benzoxazine-4,4'-peperidin]-2(1h)-one 1'-[2-[4-(TRIFLUOROMETHYL)PHENYL]ETHYL]-SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE HYDROCHLORIDE 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one,hydrochloride Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]- 1'-(4-(trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one CC chemokine receptor,CCR,Inhibitor,RS102895,inhibit,RS-102895,RS 102895 300815-41-2 C21H21F3N2O2HCl RS 102895 CCR2-selective chemokine receptor antagonist. Cytokine signaling