ChemicalBook >> CAS DataBase List >>5,8-Dioxa-2,11-diazaheptadecanedioic acid, 12-oxo-, 1-(1,1-dimethylethyl) ester
5,8-Dioxa-2,11-diazaheptadecanedioic acid, 12-oxo-, 1-(1,1-dimethylethyl) ester
- CAS No.
- 1310327-20-8
- Chemical Name:
- 5,8-Dioxa-2,11-diazaheptadecanedioic acid, 12-oxo-, 1-(1,1-dimethylethyl) ester
- Synonyms
- PROTAC Linker 30;Boc-NH-PEG2-C2-amido-C4-acid;2,2-dimethyl-4,15-dioxo-3,8,11-trioxa-5,14-diazaicosan-20-oic acid;5,8-Dioxa-2,11-diazaheptadecanedioic acid, 12-oxo-, 1-(1,1-dimethylethyl) ester
- CBNumber:
- CB65923227
- Molecular Formula:
- C17 H32 N2 O7
- Molecular Weight:
- 376.45
- MDL Number:
- MFCD32201087
- MOL File:
- 1310327-20-8.mol
Last updated:2023-02-23 14:24:01
5,8-Dioxa-2,11-diazaheptadecanedioic acid, 12-oxo-, 1-(1,1-dimethylethyl) ester Chemical Properties,Uses,Production
Biological Activity
Boc-NH-PEG2-C2-amido-C4-acid (PROTAC Linker 30) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Targ. J Med Chem. 2019 Aug 21.
5,8-Dioxa-2,11-diazaheptadecanedioic acid, 12-oxo-, 1-(1,1-dimethylethyl) ester Preparation Products And Raw materials
Raw materials
Preparation Products
5,8-Dioxa-2,11-diazaheptadecanedioic acid, 12-oxo-, 1-(1,1-dimethylethyl) ester Suppliers
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223 | psaitong@jm-bio.com | China | 29834 | 58 |
| Xi'an Qiyue Biotechnology Co., Ltd. | 400-400-6966-012-012 17778955912 | 2957605606@qq.com | China | 2535 | 58 |
| Aobolihui | 0917-18691729 18691729963 | 2553382659@qq.com | China | 4758 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 58 |
| Xi'an Qiyue Biotechnology Co., Ltd. | 58 |
| Aobolihui | 58 |
5,8-Dioxa-2,11-diazaheptadecanedioic acid, 12-oxo-, 1-(1,1-dimethylethyl) ester
Boc-NH-PEG2-C2-amido-C4-acid
PROTAC Linker 30
2,2-dimethyl-4,15-dioxo-3,8,11-trioxa-5,14-diazaicosan-20-oic acid
1310327-20-8
C17H32N2O7
peg