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Citrulline-specific Probe-rhodamine

CAS No.
2309313-01-5
Chemical Name:
Citrulline-specific Probe-rhodamine
Synonyms
Rhodamine Phenylglyoxal Monohydrate;Citrulline-specific Probe-rhodamine
CBNumber:
CB66197254
Molecular Formula:
C39H37N7O8
Molecular Weight:
731.77
MDL Number:
MOL File:
2309313-01-5.mol
Last updated:2023-05-21 10:59:17

Citrulline-specific Probe-rhodamine Properties

storage temp. Store at -20°C
solubility Acetonitrile:Water (2:1): 1 mg/ml; DMF: 1 mg/ml
form A lyophilized solid

Citrulline-specific Probe-rhodamine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16172 Citrulline-specific Probe-rhodamine ≥90% 2309313-01-5 250μg $178 2024-03-01 Buy
Cayman Chemical 16172 Citrulline-specific Probe-rhodamine ≥90% 2309313-01-5 500μg $319 2024-03-01 Buy
Cayman Chemical 16172 Citrulline-specific Probe-rhodamine ≥90% 2309313-01-5 1mg $565 2024-03-01 Buy
TRC R318610 RhodaminePhenylglyoxalHydrate 2309313-01-5 1mg $395 2021-12-16 Buy
Product number Packaging Price Buy
16172 250μg $178 Buy
16172 500μg $319 Buy
16172 1mg $565 Buy
R318610 1mg $395 Buy

Citrulline-specific Probe-rhodamine Chemical Properties,Uses,Production

Description

Protein arginine deiminases (PADs) catalyze the posttranslational modification of arginine residues on proteins to form citrulline, which plays a large role in regulating gene expression. Abnormally high PAD activity has been observed in a host of human diseases. Citrulline-specific probe-rhodamine is a highly sensitive, rhodamine phenylglyoxal-based fluorophore that specifically detects protein citrullination via a chemoselective reaction between glyoxal and citrulline. This chemical probe (comprised of a single isomer) is capable of reacting with any citrulline-containing protein and can be analyzed with fluorescent imaging (excitation 532 nm; emission 580 nm). When added at 100 μM for 30 minutes at acidic pH, this probe has a reported limit of detection of ~10 ng for citrullinated histone H3 and ~1 ng for autodeiminated PAD4.

Uses

Rhodamine Phenylglyoxal Hydrate is a citrulline-specific chemical probe which can be used to detect protein citrullination through a chemoselective reaction between glyoxal and citrulline.

Citrulline-specific Probe-rhodamine Preparation Products And Raw materials

Raw materials

Preparation Products

Citrulline-specific Probe-rhodamine Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-400-6206333 18521732826 market@aladdin-e.com China 25014 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Universal Biotech Co.,Ltd 18768175414 gaojun@univ-bio.com China 24998 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.com China 24246 58
Citrulline-specific Probe-rhodamine Rhodamine Phenylglyoxal Monohydrate 2309313-01-5