ATRANORIN
- CAS No.
- 479-20-9
- Chemical Name:
- ATRANORIN
- Synonyms
- Atrarin;USNARIN;PARMELIN;ATRANORIN;NSC-685591;ATRANORIN(P);3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl-3-formyl-2,4-dihydroxy-6-methylbenzoat;3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl 3-formyl-2,4-dihydroxy-6-methylbenzoate;Benzoic acid,3-formyl-2,4-dihydroxy-6-methyl-,3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester;3-Formyl-2,4-dihydroxy-6-methylbenzoic acid 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester
- CBNumber:
- CB6665973
- Molecular Formula:
- C19H18O8
- Molecular Weight:
- 374.34
- MDL Number:
- MFCD00016597
- MOL File:
- 479-20-9.mol
| Melting point | 156-158°C |
|---|---|
| storage temp. | Store at -20°C |
| solubility | Chloroform: soluble,DMSO: soluble |
| form | A crystalline solid |
| LogP | 6.140 (est) |
| FDA UNII | 450U2VJ2VG |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317 |
| Precautionary statements | P280-P302+P352 |
| Toxicity | skn-gpg 5% CODEDG 11,168,1984 |
ATRANORIN price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL84203 | Atranorin phyproof? Reference Substance | 479-20-9 | 10MG | $574 | 2024-03-01 | Buy |
| Cayman Chemical | 28106 | Atranorin | 479-20-9 | 500μg | $48 | 2024-03-01 | Buy |
| Cayman Chemical | 28106 | Atranorin | 479-20-9 | 1mg | $90 | 2024-03-01 | Buy |
| Cayman Chemical | 28106 | Atranorin | 479-20-9 | 5mg | $236 | 2024-03-01 | Buy |
| Cayman Chemical | 28106 | Atranorin | 479-20-9 | 10mg | $331 | 2024-03-01 | Buy |
ATRANORIN Chemical Properties,Uses,Production
Description
Atranorin is a depside lichen metabolite that has been found in S. alpinum and has diverse biological activities. It is active against the bacteria B. cereus, B. subtilis, S. aureus, S. faecalis, P. vulgaris, L. monocytogenes, and A. hydrophila (MICs = 1.67, 0.38, 26.7, 13.4, 3.34, 9.83, and 1.67 mM, respectively), the fungi C. albicans and C. glabrata (MIC = 26.7 mM for both), as well as the mycobacterium M. aurum (MIC = 250 μg/ml). Atranorin is cytotoxic to A270, HL-60, and Jurkat cancer cells (IC50s = 197.9, 93.5, and 181.6 μM, respectively) but not HeLa, MCF-7, SK-BR-3, or HT-29 cancer cells (IC50s = >200 μM). It inhibits acetic acid-induced writhing in mice when administered orally at doses of 200 and 400 mg/kg. Atranorin (200 and 400 mg/kg, p.o.) also reduces paw licking and biting in the second, but not first, phase of the formalin test when administered 30 minutes prior to formalin in mice.
Uses
antinociceptive, antiinflammatory, antibacterial
Uses
Component in extracts of oak moss used as fragrance. Atranorin is a derivative compound of Chloratranorin (C364120), which are metabolites of Evernia prunastri and functions as antioxidant, antimicrobial and potential anticancer agents.
Definition
ChEBI: Atranorin is a carbonyl compound.
Hazard
A poison by skin contact. A skin irritant.
Safety Profile
A poison by skin contact. A skin irritant. When heated to decomposition it emits acrid smoke and irritating vapors.
ATRANORIN Preparation Products And Raw materials
ATRANORIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| TopScience Biochemical | 00852-68527855 | info@itopbiochem.com | China Hong Kong | 902 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
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