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Flocoumafen

Flocoumafen
Flocoumafen structure
CAS No.
90035-08-8
Chemical Name:
Flocoumafen
Synonyms
STORM;stratgem;wl108366;Stratagen;Storm(TM);FLOCUMAFEN;FLOCOUMAFEN;flocoumafene;aphthyl)coumarin;Storm(rodenticide)
CBNumber:
CB6671271
Molecular Formula:
C33H25F3O4
Formula Weight:
542.54
MOL File:
90035-08-8.mol

Flocoumafen Properties

Melting point:
181 °C
Boiling point:
672.4±55.0 °C(Predicted)
Density 
1.2 g/cm3
vapor pressure 
1.33 x l0-10 Pa (25 °C)
Flash point:
23 °C
form 
neat
Water Solubility 
1.1 mg l-1
pka
4.50±1.00(Predicted)
InChIKey
KKBGNYHHEIAGOH-UHFFFAOYSA-N
FDA UNII
2Z80062XQ4
EPA Substance Registry System
2H-1-Benzopyran-2-one, 4-hydroxy-3-[1,2,3,4-tetrahydro-3-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]-1-naphthalenyl]- (90035-08-8)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H300-H310-H330-H372-H410
Precautionary statements  P273-P314-P501
Hazard Codes  T+,N
Risk Statements  26/27/28-48/23/24/25-50/53
Safety Statements  28-36/37/39-45-60-61
RIDADR  3027
WGK Germany  3
RTECS  DJ3100300
HazardClass  6.1(a)
PackingGroup  I
Toxicity LD50 in rats, mice, rabbits (mg/kg): 0.25, 0.8, 0.2 orally (Bowler)

Flocoumafen price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 34084 Flocoumafen mixture of isomers 90035-08-8 50mg $161 2021-03-22 Buy

Flocoumafen Chemical Properties,Uses,Production

Uses

Flocoumafen is a second-generation anti-coagulant used as a rodenticide. It has a very high toxicity and is restricted to indoor use and sewers (in the United Kingdom). This restriction is mainly due to the increased risk to non-target species. Studies have shown that rodents resistant to first-generation anti-coagulants can be adequately controlled with flocoumafen. The chemical substance is off-white solid, does not mix well with water (1.1 mg/L), and is sparingly soluble in acetone, ethanol, xylene, and octanol. Flocoumafen is stable to hydrolysis. Because of the acute toxicity of flocoumafen and its intended use as a rodenticide, chronic toxicity studies have not been reported. However, flocoumafen is known to cause adverse health effects and abnormal prothrombin.

Uses

Rodenticide.

Uses

Flocoumafen is used to control rodents around buildings. It also has some use in field and plantation crops including cocoa, cotton, oilpalm, rice and sugar cane.

Metabolic pathway

Flocoumafen exists as cis and trans isomers (Scheme 1). The tetralin ring adopts its most stable conformation in each case and the two forms have very similar shapes. Both are active rodenticides. The fate of flocoumafen in soils and plants has not been studied in detail because the compound is usually used as a pelleted bait or in a wax block. This limits its dissipation in the environment. Studies in animals and birds have been conducted as part of the assessment of safety and to investigate mode of action. Metabolism is slow in the rat and rapid in Japanese quail but this difference should be interpreted with care because of the 100-fold difference in dose used (see also Overview).

Degradation

Flocoumafen is a stable compound; no detectable degradation occurs at 50 °C at pH 7-9 over 4 weeks.

Flocoumafen Preparation Products And Raw materials

Raw materials

Preparation Products

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