Thioflavine T
- CAS No.
- 2390-54-7
- Chemical Name:
- Thioflavine T
- Synonyms
- THIOFLAVIN T;avin T;ThiofL;CI 49005;CI NO 49005;hioflavineT;Setoflavin T;THIOFLAVINE T;SETOFLAVINE T;BASIC YELLOW 1
- CBNumber:
- CB6676791
- Molecular Formula:
- C17H19ClN2S
- Molecular Weight:
- 318.86
- MDL Number:
- MFCD00011944
- MOL File:
- 2390-54-7.mol
Melting point | 211-212 °C (decomp) |
---|---|
Density | 1.301g/cm3 at 20℃ |
vapor pressure | 0Pa at 25℃ |
storage temp. | Store below +30°C. |
solubility | methanol: soluble1mg/mL |
Colour Index | 49005 |
form | Powder |
color | Yellow to ochre-yellow |
BRN | 3922452 |
LogP | 3.02 at 25℃ and pH7.98 |
CAS DataBase Reference | 2390-54-7(CAS DataBase Reference) |
FDA UNII | CAX9SG0II0 |
EPA Substance Registry System | Benzothiazolium, 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-, chloride (2390-54-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H332-H335 | |||||||||
Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
Safety Statements | 24/25 | |||||||||
RIDADR | 2811 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 6.1(b) | |||||||||
PackingGroup | III | |||||||||
HS Code | 32041300 | |||||||||
NFPA 704 |
|
Thioflavine T price More Price(37)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | T3516 | Thioflavin T used as stain for amyloid | 2390-54-7 | 5g | $36.6 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.40072 | Thioflavine T (C.I.No.49005) ≥73% sulfur basis | 2390-54-7 | 5G | $102 | 2024-03-01 | Buy |
Sigma-Aldrich | 596200 | Thioflavin T | 2390-54-7 | 500mg | $123 | 2024-03-01 | Buy |
TCI Chemical | T0558 | Basic Yellow 1 | 2390-54-7 | 25g | $73 | 2024-03-01 | Buy |
Alfa Aesar | J61043 | Thioflavine T, tech. 75% | 2390-54-7 | 5g | $21.65 | 2024-03-01 | Buy |
Thioflavine T Chemical Properties,Uses,Production
Chemical Properties
yellow to ochre-yellow powder
Uses
A dye used to visualize beta-amyloid plaques, like those associated with Alzheimer's Disease
Uses
Textile dyeing, fluorescent sign paints, in combination with green or blue pigments to produce brilliant greens, phosphotungstic pigments.
Definition
ChEBI: Thioflavine T is an organic chloride salt having 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium as the counterion. It is widely used to visualise and quantify the presence of amyloids, both in vitro and in vivo. It has a role as a fluorochrome, a histological dye and a geroprotector. It contains a thioflavin T cation.
Preparation
4-(6-Methyl-2,3-dihydrobenzo[d]thiazol-2-yl)benzenamine?with methanol and hydrochloric acid or sulfuric acid, at 160 ~ 170 ℃ methylation under pressure.
General Description
Thioflavin T is a benzothiazole dye that increases in fluorescence upon binding to amyloid. Thioflavin T has been used in histology and for protein characterization.
Biochem/physiol Actions
Cell permeable: yes
storage
Store at -20°C
Properties and Applications
colourful green light yellow. Soluble in cold water, soluble in hot water for yellow, easily soluble in ethanol and yellow, with green fluorescent. The strong sulfuric acid to colorless, a green fluorescent, diluted into light yellow.
Standard( Silk ) | Light Fastness | Persperation Fastness | Ironing Fastness | Soaping | |||
Fading | Stain | Fading | Stain | Fading | Stain | ||
C | 3 | 2-3 | 4 | 1 |
Purification Methods
Crystallise the chloride from *benzene/EtOH (1:1). [Beilstein 27 III/IV 5052.]
Thioflavine T Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Honest Joy Holdings Limited | 0755-36694831 +8613717124449 | sale@feiyang.com.cn | China | 300 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12446 | 58 |
Hubei Lidu New Material Technology Co., Ltd | +undefined+86-19307248857 | liduxcl@163.com | China | 131 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21667 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Win-Win Chemical CO., Limited | 0086-577-64498589 | sales@win-winchemical.com | CHINA | 998 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8820 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
View Lastest Price from Thioflavine T manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-23 | THIOFLAVIN T
2390-54-7
|
US $0.00-0.00 / kg | 1kg | 99% | 20tons | Hubei Lidu New Material Technology Co., Ltd | ||
2024-04-24 | Thioflavine T
2390-54-7
|
US $10.00 / kg | 1kg | 99.9% | 200000kg | Ouhuang Engineering Materials (Hubei) Co., Ltd | ||
2023-06-22 | Thioflavine T
2390-54-7
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
- THIOFLAVIN T
2390-54-7
- US $0.00-0.00 / kg
- 99%
- Hubei Lidu New Material Technology Co., Ltd
- Thioflavine T
2390-54-7
- US $10.00 / kg
- 99.9%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
- Thioflavine T
2390-54-7
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd