ChemicalBook >> CAS DataBase List >>8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE

8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE

8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE structure

CAS No.: 51116-01-9

Chemical Name:: 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE

Synonyms: BR-CGMP, NA;8-BR-CGMP NA;8-BROMO-CGMP NA;Einecs 256-993-8;8-BROMO-CGMP SODIUM;8-BR-CGMP SODIUM SALT;(115974-70-4) 8-AET-cGMP;8-BROMO-CGMP, SODIUM SALT;8-bromo-Cyclic GMP (sodium salt);8 Bromo cGMP sodium,8BromocGMP sodium

CBNumber:: CB6687726

Molecular Formula:: C10H12BrN5NaO7P

Molecular Weight:: 448.1

MDL Number:: MFCD03703483

MOL File:: 51116-01-9.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

Request For Quotation

8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Properties

storage temp.	-20°C
solubility	H₂O: 100 mg/mL
form	powder
Water Solubility	Soluble to 100 mM in water

SAFETY

Risk and Safety Statements

WGK Germany	3
F	10-21
HS Code	29349990

8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	B1381	8-Bromoguanosine 3′,5′-cyclic monophosphate sodium salt ≥98% (HPLC), powder	51116-01-9	10mg	$89.4	2024-03-01	Buy
Sigma-Aldrich	203820	Guanosine 3?,5?-cyclic Monophosphate, 8-Bromo-, Sodium Salt	51116-01-9	25mg	$166	2024-03-01	Buy
Cayman Chemical	15992	8-bromo-Cyclic GMP (sodium salt) ≥98%	51116-01-9	5mg	$44	2024-03-01	Buy
Cayman Chemical	15992	8-bromo-Cyclic GMP (sodium salt) ≥98%	51116-01-9	10mg	$74	2024-03-01	Buy
Sigma-Aldrich	B1381	8-Bromoguanosine 3′,5′-cyclic monophosphate sodium salt ≥98% (HPLC), powder	51116-01-9	25mg	$179	2024-03-01	Buy

Product number	Packaging	Price	Buy
B1381	10mg	$89.4	Buy
203820	25mg	$166	Buy
15992	5mg	$44	Buy
15992	10mg	$74	Buy
B1381	25mg	$179	Buy

8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Chemical Properties,Uses,Production

Description

8-bromo-Cyclic GMP (8-bromo-cGMP) is a cell-permeable analog of cGMP that exhibits greater resistance to hydrolysis by phosphodiesterases than its parent compound. It preferentially activates cGMP-dependent protein kinase. At 1 μM-0.1 mM, 8-bromo-cGMP can inhibit acetylcholine-induced increases in intracellular calcium concentrations.

Chemical Properties

White powder

Uses

8-bromo-cGMP activates cGMP-dependent protein kinase. It can also inhibit acetylcholine-induced increases in intracellular calcium concentrations.

Definition

ChEBI: Sodium 8-bromo-3',5'-cyclic GMP is an organic sodium salt having 8-bromoguanosine 3',5'-cyclic phosphate as the counterion. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro. It has a role as a protein kinase G agonist and a muscle relaxant. It contains an 8-bromo-3',5'-cyclic GMP(1-).

Biological Activity

Membrane permeable cGMP analog that activates protein kinase G (PKG). 4.3-fold more potent than cGMP in activating PKG1 α and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro .

storage

Desiccate at -20°C

8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Suppliers

Global( 56)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	10027	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
BOC Sciences	58
NewCan Biotech Limited	58
Aladdin Scientific	58
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Sigma-Aldrich	80
EMMX Biotechnology LLC	60
Shanghai EFE Biological Technology Co., Ltd.	58

51116-01-9(8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE)Related Search:

Guanosine 5'-monophosphate disodium salt Guanosine ADP 2-BROMO-4-METHYL-1H-IMIDAZOLE 2-BROMO-1-ETHOXYMETHYLIMIDAZOLE

8-BROMO-2'-DEOXYGUANOSINE GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT 8-Bromoguanosine 2-Bromo-1-methyl-1H-imidazole 2-BROMO-1,4-DIMETHYL-1H-IMIDAZOLE

8-BR-CGMP 8-BR-PET-CGMP SODIUM SALT INOSINE-3',5'-CYCLIC PHOSPHATE 8-BROMOGUANINE 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE

8-BROMOHYPOXANTHINE 2'-DCGMP SODIUM SALT 9-((2-hydroxy-1,3,2-dioxaphosphorinan-5-yl)oxymethyl)guanine P-oxide

1of4

8-bromoguanosine-3’,5’-cyclicmonophosphate(8-br-cgmp),sodiumsalt, 8-bromoguanosine 3:5-cyclic*monophosphate sodiu 8-Bromoguanosine-3,5-cyclomonophosphate sodium salt Guanosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate), monosodium salt 8-BROMOGUANOSINE 3':5'-CYCLICMONOPHOSPHA TE SODIUM 8-BROMO-CGMP SODIUM SALT 8-BROMOGUANOSIN E-3',5 GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE, 8-BROMO-, SODIUM SALT BR-CGMP, NA 8-BR-CGMP NA 8-BR-CGMP SODIUM SALT 8-BROMO-CGMP NA 8-BROMO-CGMP SODIUM 8-BROMO-CGMP, SODIUM SALT 8-BROMOGUANOSINE CYCLIC 3',5'-MONOPHOSPHATE SODIUM SALT 8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE 8-BROMOGUANOSINE-3',5'-CYCLOPHOSPHATE SODIUM 8-BROMOGUANOSINE-3',5'-CYCLOPHOSPHATE SODIUM SALT 8-BROMOGUANOSINE-3,5-CYCLICMONOPHOSPHATESODIUMSALT,ULTRAPURE Einecs 256-993-8 (115974-70-4) 8-AET-cGMP 8-bromo-Cyclic GMP (sodium salt) Guanosine 3,5-cyclic Monophosphate, 8-Bromo-, Sodium Salt - CAS 51116-01-9 - Calbiochem 8-Bromoguanosine3′,5′-cyclicmonophosphatesodiumsal 8 Bromo cGMP sodium,8BromocGMP sodium 51116-01-9 C10H10BrN5NaO7P C10H10BrN5O7PNa Cell Biology Cell Signaling and Neuroscience Biochemicals and Reagents BioChemical G Proteins and Cyclic Nucleotides Cyclic Nucleotide Metabolism Cyclic Nucleotides and Analogs Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides Cyclic Nucleotide related Cyclic Nucleotide Metabolism Cyclic Nucleotides and AnalogsSerine/Threonine Kinase Biology G Proteins and Cyclic Nucleotides Protein Kinase G (PKG) Serine/Threonine Kinase Activators