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Pyrazole

CAS No.
288-13-1
Chemical Name:
Pyrazole
Synonyms
1H-PYRAZOLE;PYRAZOL;1H-Pyrazol;Pyrrazole;Pyrazole, pure, 98%;PYRAZOLE;Ryrazole;1,2-DIAZOL;1,2-DIAZOLE;Pyrazole>
CBNumber:
CB6689669
Molecular Formula:
C3H4N2
Molecular Weight:
68.08
MDL Number:
MFCD00005234
MOL File:
288-13-1.mol
MSDS File:
SDS
Last updated:2024-01-16 16:12:45

Pyrazole Properties

Melting point 67-70 °C (lit.)
Boiling point 186-188 °C (lit.)
Density 1.4088 (rough estimate)
vapor pressure 21Pa at 20℃
refractive index 1.4203
Flash point 186-188°C
storage temp. Store below +30°C.
solubility Chloroform, Methanol
form Crystals or Crystalline Powder
pka 2.49(at 25℃)
color White to yellow
Water Solubility SOLUBLE
Sensitive Hygroscopic
Merck 14,7960
BRN 103775
InChIKey WTKZEGDFNFYCGP-UHFFFAOYSA-N
LogP 0.33 at 25℃
CAS DataBase Reference 288-13-1(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 3QD5KJZ7ZJ
NIST Chemistry Reference 1H-Pyrazole(288-13-1)
EPA Substance Registry System Pyrazole (288-13-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS06,GHS08
Signal word  Danger
Hazard statements  H302-H311-H315-H318-H373-H412
Precautionary statements  P273-P280-P301+P312-P302+P352+P312-P305+P351+P338-P314
Hazard Codes  Xn
Risk Statements  22-36/37/38-52-20/21/22
Safety Statements  26-36/37-61-37/39-36
RIDADR  2811
WGK Germany  1
RTECS  UQ4900000
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  29331990
Toxicity LD50 (24 hr) in rats, mice (mmol/kg): 19, 21 i.v.; 21, 22 orally (Magnussen)
NFPA 704
1
2 0

Pyrazole price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P56607 Pyrazole 98% 288-13-1 5g $17.9 2024-03-01 Buy
Sigma-Aldrich P56607 Pyrazole 98% 288-13-1 25g $63.8 2024-03-01 Buy
Sigma-Aldrich 8.07572 Pyrazole for synthesis 288-13-1 25g $86 2024-03-01 Buy
TCI Chemical P0546 Pyrazole >98.0%(GC)(T) 288-13-1 25g $43 2024-03-01 Buy
TCI Chemical P0546 Pyrazole >98.0%(GC)(T) 288-13-1 250g $118 2024-03-01 Buy
Product number Packaging Price Buy
P56607 5g $17.9 Buy
P56607 25g $63.8 Buy
8.07572 25g $86 Buy
P0546 25g $43 Buy
P0546 250g $118 Buy

Pyrazole Chemical Properties,Uses,Production

Chemical Properties

white to yellow crystals or crystalline powder

Uses

Pyrazole is used in organic synthesis and asa chelating agent.

Definition

ChEBI: 1H-pyrazole is the 1H-tautomer of pyrazole. It is a conjugate base of a pyrazolium. It is a conjugate acid of a pyrazol-1-ide. It is a tautomer of a 3H-pyrazole and a 4H-pyrazole.

General Description

Pyrazine is a heterocyclic crystalline aromatic compound with a five-membered ring containing three carbon atoms and two nitrogen atoms. It is a symmetricdiazine.

Hazard

Toxic by ingestion and inhalation, irritant to skin and eyes.

Health Hazard

The acute toxic symptoms from oral administrationof pyrazole in experimental animalswere ataxia, muscle weakness, and respiratorydepression. It is less toxic than pyrroleand pyrrolidine. The oral LD50 value in miceis within the range 1450 mg/kg.
Pyrazole exhibited reproductive toxicityin rats and mice when administered by oralor intraperitoneal route. The effects includefetal death, developmental abnormalities pertainingto the urogenital system, and postimplantationmortality.

Fire Hazard

Noncombustible solid.

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise pyrazole from pet ether, cyclohexane, or water. Its solubility in H2O at 9.6o is 2.7moles/L, and at 24.8o it is 19.4moles/L; in cyclohexane at 31.8o it is 0.577moles/L, and at 56.2o it is 5.86moles/L; and in benzene at 5.2o it is 0.31moles/L, and at 46.5o it is 16.8moles/1000mL. [Barszcz et al. J Chem Soc, Dalton Trans 2025 1986, Beilstein 23 H 39, 23 I 15, 23 II 33, 23 III/IV 550, 23/4 V 122.]

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View Lastest Price from Pyrazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pyrazole pictures 2024-04-25 Pyrazole
288-13-1
US $14000.00-1200000.00 / kg 1000kg 99% 500 tons Ningxia Jinhua Chemical Co.,Ltd
Pyrazole pictures 2024-04-25 Pyrazole
288-13-1
US $14000.00-1200000.00 / kg 1000kg 99% 500 tons Changde Changlian Chemical Co., Ltd.
Pyrazole pictures 2024-04-24 Pyrazole
288-13-1
US $14000.00-1200000.00 / kg 1000kg 99% 500 tons Gansu Jinyuantai New Material Co., Ltd.
  • Pyrazole pictures
  • Pyrazole
    288-13-1
  • US $14000.00-1200000.00 / kg
  • 99%
  • Ningxia Jinhua Chemical Co.,Ltd
  • Pyrazole pictures
  • Pyrazole
    288-13-1
  • US $14000.00-1200000.00 / kg
  • 99%
  • Changde Changlian Chemical Co., Ltd.
  • Pyrazole pictures
  • Pyrazole
    288-13-1
  • US $14000.00-1200000.00 / kg
  • 99%
  • Gansu Jinyuantai New Material Co., Ltd.
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