ChemicalBook
Chinese Japanese Germany Korea

ALL-TRANS-RETINAL

ALL-TRANS-RETINAL
ALL-TRANS-RETINAL structure
CAS No.
116-31-4
Chemical Name:
ALL-TRANS-RETINAL
Synonyms
Retinene;Retinene1;E-Retinal;Axerophthal;Retinaldehyde;all-E-Retinal;trans-Retinal;alpha-Retinene;Nanoactive RAL;Retinylaldehyde
CBNumber:
CB6703879
Molecular Formula:
C20H28O
Formula Weight:
284.44
MOL File:
116-31-4.mol

ALL-TRANS-RETINAL Properties

Melting point:
61-63°C
Boiling point:
366.92°C (rough estimate)
Density 
1.0083 (rough estimate)
refractive index 
1.4500 (estimate)
storage temp. 
-20°C
form 
powder
color 
yellow
Water Solubility 
<70mg/L(25 ºC)
CAS DataBase Reference
116-31-4(CAS DataBase Reference)
FDA UNII
RR725D715M
EPA Substance Registry System
Retinal (116-31-4)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315
Hazard Codes  Xn
Risk Statements  22-38
Safety Statements  22-36/37
WGK Germany  3
RTECS  VH6407000
HS Code  29122990
NFPA 704
0
1 0

ALL-TRANS-RETINAL price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R2500 all trans-Retinal powder, ≥98% 116-31-4 25mg $55.3 2021-12-16 Buy
Sigma-Aldrich R2500 all trans-Retinal powder, ≥98% 116-31-4 1g $308 2021-12-16 Buy
Cayman Chemical 18449 all-trans Retinal ≥98% 116-31-4 100mg $35 2021-12-16 Buy
Cayman Chemical 18449 all-trans Retinal ≥98% 116-31-4 1g $193 2021-12-16 Buy
TRC R240000 all trans-Retinal 116-31-4 25mg $50 2021-12-16 Buy

ALL-TRANS-RETINAL Chemical Properties,Uses,Production

Chemical Properties

Yellow Powder

Uses

Corotenoid component of the visual pigments. All-trans retinal is converted to retinoic acid in vivo by the action of retinal dehydrogenase.

Uses

retinaldehyde is a mild retinoid credited with increasing epidermal thickness without producing erythema.

Uses

All trans-Retinal has been used:
  • in optogenetic experiments
  • in electrophysiological experiment
  • to study the effect of AKR1B10 (aldo-keto reductase (AKR) superfamily member) on the conversion of retinal to retinol in the airway epithelium
  • in decidual transformation of human endometrial stromal cells

Definition

ChEBI: A retinal in which all four exocyclic double bonds have E- (trans-) geometry.

Synthesis Reference(s)

Tetrahedron Letters, 29, p. 419, 1988 DOI: 10.1016/S0040-4039(00)80111-2

General Description

All trans-Retinal is one of the major derivatives of vitamin A group. A variety of food serves as a source of vitamin A. It is predominant in liver and among the brightly colored vegetables.

Biochem/physiol Actions

All-trans retinal is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells. Retinal isomers are also chromophores that bind to opsins, a family of G-protein-linked transmembrane proteins, to form photosensitive receptors in visual and nonvisual systems. All-trans retinal is a potent photosensitizer.

Purification Methods

The aldehyde is separated from retinol by column chromatography on water-deactivated alumina. Elute with 1-2% acetone in hexane, or on TLC plates of silica gel G and using the same eluting solvent. It crystallises from pet ether or n-hexane as yellow-orange crystals, and the UV in hexane has max at 373nm (A1cm 1% 1,548) and 368nm ( 48,000). It is an irritant and is light sensitive. Store it in sealed ampoules under N2. The semicarbazone forms yellow crystals from CHCl3/Et2O or EtOH, m 199-201o(dec). The 9-cis-isomer [514-85-2] and the 13-cis-isomer [472-86-6] [max at 375nm ( 1,250) in EtOH] are also available commercially. [Beilstein 7 III 1742.]

ALL-TRANS-RETINAL Preparation Products And Raw materials

Raw materials

Preparation Products


ALL-TRANS-RETINAL Suppliers

Global( 176)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
86-021-61999440
contact@trustwe.com CHINA 10008 58
Dayang Chem (Hangzhou) Co.,Ltd.
17705817739 +86-571-88938639
+86-571-88938652,+86-571- 88492614 info@dycnchem.com CHINA 52932 58
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 15427 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 9128 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3013 60
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26782 60
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29954 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2940 58
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 968 58

View Lastest Price from ALL-TRANS-RETINAL manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2022-01-19 All-trans-retinal
116-31-4
US $2.30 / KG 100g 99% 20 Hong Kong Tiansheng New Material Trading Co., Ltd
2021-12-01 Retinaldehyde
116-31-4
US $10.00 / Kg/Drum 1KG 98% 10 ton Hebei Crovell Biotech Co Ltd
2021-11-09 alltransretinal
116-31-4
US $0.00 / KG 2KG 98% up by hplc 20 tons Sinoway Industrial co., ltd.

116-31-4(ALL-TRANS-RETINAL)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved