IKD-8344
- CAS No.
- 129046-69-1
- Chemical Name:
- IKD-8344
- Synonyms
- IKD-8344;(1R,2R,5S,8S,9S,12R,14S,17R,18R,21S,24S,25S,28R,30S)-rel-2,9,18,25-tetramethyl-12,28-bis[(1S)-1-[(2S,5R)-tetrahydro-5-methyl-2-furanyl]ethyl]-11,27,33,34,35,36-hexaoxapentacyclo[28.2.1.15,8.114,17.121,24]hexatriacontane-3,10,19,26-tetrone
- CBNumber:
- CB6708728
- Molecular Formula:
- C48H76O12
- Molecular Weight:
- 845.11
- MDL Number:
- MFCD00916500
- MOL File:
- Mol file
IKD-8344 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28194 | IKD-8344 | 129046-69-1 | 1mg | $364 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | API0025514 | IKD-8344 95.00% | 129046-69-1 | 5MG | $496.66 | 2021-12-16 | Buy |
| Apolloscientific | BIBR1143 | IKD-8344 | 129046-69-1 | 1mg | $338 | 2021-12-16 | Buy |
IKD-8344 Chemical Properties,Uses,Production
Description
IKD-8344 is a macrocyclic dilactone originally isolated from an actinomycete species and has diverse biological activities, including anticancer, antimicrobial, and anthelmintic properties.1,2,3 It is cytotoxic to L5178Y murine leukemia cells (IC50 = 0.54 ng/ml).1 IKD-8344 inhibits growth of the mycelial form of C. albicans (MIC = 6.25 μg/ml) and potentiates the activity of polymyxin B against the multidrug-resistant pathogenic bacterium B. cenocepacia.2,3 It is active against T. spiralis in vitro and in vivo.1
References
1. Minami, Y., Yoshida, K., Azuma, R., et al. Structure of a novel macrodiolide antibiotic IKD-
2. Hwang, E.I., Yun, B.S., Yeo, W.H., et al. Compound IKD-
3. Loutet, S.A., El-Halfawy, O.M., Jassem, A.N., et al. Identification of synergists that potentiate the action of polymyxin B against Burkholderia cenocepacia Int. J. Antimicrob. Agents 46(4),376-380(2015).
IKD-8344 Preparation Products And Raw materials
Raw materials
Preparation Products
IKD-8344 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |