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SULBENICILLIN

SULBENICILLIN structure

CAS No.: 41744-40-5

Chemical Name:: SULBENICILLIN

Synonyms: SBPC;Kedacillina;Subenicillin;SULBENICILLIN;Sulbenicilina;(R)-Sulbenicillin;D-(-)-Sulbenicillin;Sulbenicillin, D-(-)-;a-Sulfobenzylpenicillin;SULBENICILLIN USP/EP/BP

CBNumber:: CB6715306

Molecular Formula:: C16H18N2O7S2

Molecular Weight:: 414.45

MDL Number:: MFCD00869408

MOL File:: 41744-40-5.mol

MSDS File:: SDS

Last updated:2022-12-21 16:56:50

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SULBENICILLIN Properties

Melting point	197 °C (decomp)
Density	1?+-.0.1 g/cm3(Predicted)
pka	0.28±0.50(Predicted)
FDA UNII	Q2VYF0562D
ATC code	J01CA16

SULBENICILLIN price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	API0013659	SULBENICILLIN 98.00%	41744-40-5	1G	$1709.4	2021-12-16	Buy
AvaChem	2843	Sulbenicillin	41744-40-5	10mg	$39	2021-12-16	Buy
AvaChem	2843	Sulbenicillin	41744-40-5	25mg	$59	2021-12-16	Buy
AvaChem	2843	Sulbenicillin	41744-40-5	100mg	$129	2021-12-16	Buy

Product number	Packaging	Price	Buy
API0013659	1G	$1709.4	Buy
2843	10mg	$39	Buy
2843	25mg	$59	Buy
2843	100mg	$129	Buy

SULBENICILLIN Chemical Properties,Uses,Production

Originator

Lillacillin,Takeda,Japan,1973

Definition

ChEBI: A penicillin antibiotic having a 6beta-[phenyl(sulfo)acetamido] side-chain.

Manufacturing Process

To a suspension of 1.08 parts by weight of 6-aminopenicillanic acid in 8 parts by volume of water is added 1.48 parts by weight of sodium bicarbonate. After the mixture is dissolved, a solution of 1.18 parts by weight of α-sulfophenylacetyl chloride in 10 parts by volume of diethylether is gradually added thereto. The mixture is stirred at a temperature in the neighborhood of 0°C for 1 hour. The aqueous layer is washed twice with 10 parts by volume of portions of ether and adjusted to pH 1.2 with cation exchange resin of polystyrene sulfonic acid type under constant cooling. Then the solution is washed twice with 15 parts by volume of portions of ethyl acetate, followed by extraction twice with 15 parts by volume of portions of n-butanol. The extracts are combined and washed twice with 15 parts by volume of portions of water and, then, extracted with an aqueous solution of sodium bicarbonate. The extract is adjusted to pH 6.5, washed with ether and lyophilized to give the sodium salt of α-sulfobenzylpenicillin. Yield is 1.2 parts by weight.

Therapeutic Function

Antibacterial

Antimicrobial activity

α-Sulfobenzylpenicillin, a semisynthetic penicillin supplied as the disodium salt. Its antimicrobial spectrum and pharmacokinetic pharmacokinetic behavior closely resemble those of carbenicillin. Following intravenous administration of 4 g, the mean plasma concentration at 1 h was approximately 160 mg/L, with a plasma elimination half-life of around 70 min. It is largely excreted in the urine, about 80% of the dose appearing in the first 24 h, less than 5% as the penicilloic acid. It has been noted that the penicilloic acid causes much stronger platelet aggregation than its parent. It is of very limited availability.

SULBENICILLIN Preparation Products And Raw materials

Raw materials

6-Aminopenicillanic acid

Preparation Products

SULBENICILLIN Suppliers

Global( 50)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-18789408387	1057@dideu.com	China	3537	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9320	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29220	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
ZHEJIANG JIUZHOU CHEM CO., LTD	+86-0576225566889 +86-13454675544	admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com	China	20000	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Shaanxi Dideu Medichem Co. Ltd	58
TargetMol Chemicals Inc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Shaanxi Dideu Medichem Co. Ltd	58
Dideu Industries Group Limited	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
ZHEJIANG JIUZHOU CHEM CO., LTD	58

View Lastest Price from SULBENICILLIN manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-06-28	SULBENICILLIN USP/EP/BP 41744-40-5	US $1.10 / g	1g	99.9%	100 Tons Min	Dideu Industries Group Limited
2020-05-12	Sulbenicillin 41744-40-5	US $1.00 / KG	1KG	99%	20T	Shaanxi Dideu Medichem Co. Ltd
2019-12-26	SULBENICILLIN 41744-40-5	US $1.00 / g	1g	≥98%	g/kg/Ton	Career Henan Chemical Co

SULBENICILLIN USP/EP/BP
41744-40-5
US $1.10 / g
99.9%
Dideu Industries Group Limited

Sulbenicillin
41744-40-5
US $1.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

SULBENICILLIN
41744-40-5
US $1.00 / g
≥98%
Career Henan Chemical Co

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SULBENICILLIN Subenicillin 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylsulfoacetyl)amino]-, [2S-[2a,5a,6b(S*)]]- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-phenylsulfoacetyl]amino]-, (2S,5R,6R)- (9CI) a-Sulfobenzylpenicillin D-(-)-Sulbenicillin SBPC Sulbenicillin, D-(-)- (2S,5β)-3,3-Dimethyl-7-oxo-6α-[[(R)-phenyl(sulfo)acetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid (R)-Sulbenicillin 6α-[(R)-Phenyl(sulfo)acetylamino]penicillanic acid (2S,5R,6R)-6-((S)-Carbamoyl(phenyl)methanesulfonoyl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenyl-2-sulfoacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenyl-2-sulfo-ethanoyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (2S,5R,6R)-7-keto-3,3-dimethyl-6-[(2-phenyl-2-sulfo-acetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-2-phenyl-2-sulfoacetyl]amino]-, (2S,5R,6R)- SULBENICILLIN USP/EP/BP Kedacillina Sulbenicilina 41744-40-5