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Prednisone

Prednisone
Prednisone structure
CAS No.
53-03-2
Chemical Name:
Prednisone
Synonyms
MOPP;u6020;Cortan;Deltra;Cotone;deltae;U 6020;Wojtab;delta-E;In-Sone
CBNumber:
CB6716222
Molecular Formula:
C21H26O5
Formula Weight:
358.43
MOL File:
53-03-2.mol

Prednisone Properties

Melting point:
236-238 °C(lit.)
alpha 
169 º (c=0.5, dioxane)
Boiling point:
410.86°C (rough estimate)
Density 
1.1121 (rough estimate)
refractive index 
170 ° (C=0.5, Dioxane)
Flash point:
>200℃
storage temp. 
Refrigerator
solubility 
Practically insoluble in water, slightly soluble in ethanol (96 per cent) and in methylene chloride. It shows polymorphism (5.9).
Merck 
7722
BRN 
2065301
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
53-03-2(CAS DataBase Reference)
NIST Chemistry Reference
Prednisone(53-03-2)
EPA Substance Registry System
Pregna-1,4-diene- 3,11,20-trione, 17,21-dihydroxy-(53-03-2)

SAFETY

Hazard Codes  Xn,C,F
Risk Statements  63-34-11
Safety Statements  36/37/39-45-26-16
RIDADR  UN 1648 3 / PGII
WGK Germany  3
RTECS  TU4154100
HazardClass  IRRITANT
HS Code  29379000
Hazardous Substances Data 53-03-2(Hazardous Substances Data)

Prednisone price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 20677 Prednisone ≥98% 53-03-2 1g $25 2018-11-19 Buy
Cayman Chemical 20677 Prednisone ≥98% 53-03-2 5g $113 2018-11-19 Buy
Cayman Chemical 20677 Prednisone ≥98% 53-03-2 10g $200 2018-11-19 Buy
Cayman Chemical 20677 Prednisone ≥98% 53-03-2 25g $375 2018-11-19 Buy

Prednisone Chemical Properties,Uses,Production

Chemical Properties

White or almost white, crystalline powder.

Uses

Adrenocortical steroid. Glucocorticoid, antiinflammatory.

Uses

Downregulates TNF-α production and NF-κB expression

Definition

ChEBI: A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead f the oxo group at position 11), which is the active drug and also a steroid.

brand name

Cortan (Halsey); Delta-Dome (Bayer); Deltasone (Pharmacia & Upjohn); Liquid Pred (Muro); Meticorten (Schering); Orasone (Solvay Pharmaceuticals); Paracort (Parke-Davis).

General Description

Odorless white crystalline powder.

General Description

Prednisone, Δ1-cortisone, 17,21-dihydroxypregna-1,4-diene-3,11,20-trione, has systemic activityvery similar to that of prednisolone, and because of itslower salt-retention activity, it is often preferred over cortisoneor hydrocortisone. Prednisone must be reduced in vivoto prednisolone to provide the active GC.

Air & Water Reactions

Very slightly water soluble .

Hazard

Questionable carcinogen.

Safety Profile

Poison by intraperitoneal and subcutaneous routes. Moderately toxic by intramuscular route. Human systemic effects: sensory change involving peripheral nerves, dermatitis. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. Has been implicated in aplastic anemia.

Purification Methods

Crystallise prednisone from acetone/hexane, then recrystallise it from Me2CO. The monoacetate crystallises from Me2CO/hexane with m 227-233o(dec), [] D +186o (c 1, dioxane), and the diacetate crystallises from 25Me2CO/hexane with m 219-221o(dec), [] D +125o (c 1, CHCl3). [Hertzog et al. Tetrahedron 18 581 1962, Beilstein 8 IV 3531.]

Prednisone Preparation Products And Raw materials

Raw materials

Preparation Products


Prednisone Suppliers

Global( 242)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1530 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
PI & PI BIOTECH INC.
020-81716320
020-81716319 Sales@pipitech.com CHINA 2548 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 552 55
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24118 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20229 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19997 58

View Lastest Price from Prednisone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-17 Prednisone
53-03-2
US $7.00 / kg 1kg 99% 100KG career henan chemical co
2018-03-09 Prednisone
53-03-2
US $10.00 / KG 10G 99%min 100kg/week Hubei XinRunde Chemical Co., Ltd.

Prednisone Spectrum


53-03-2(Prednisone)Related Search:


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