BMY 45778
- CAS No.
- 152575-66-1
- Chemical Name:
- BMY 45778
- Synonyms
- BMY 45778;BMY 45778 >=98% (HPLC);[3-(4,5-DIPHENYL[2,4'-BIOXAZOL]-5'-YL)PHENOXY]ACETIC ACID;Acetic acid, 2-[3-(4,5-diphenyl[2,4'-bioxazol]-5'-yl)phenoxy]-
- CBNumber:
- CB6723653
- Molecular Formula:
- C26H18N2O5
- Molecular Weight:
- 438.43
- MDL Number:
- MFCD00917043
- MOL File:
- 152575-66-1.mol
- MSDS File:
- SDS
BMY 45778 price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | BM0032 | BMY 45778 ≥98% (HPLC) | 152575-66-1 | 25mg | $402 | 2022-05-15 | Buy |
| Tocris | 1442 | BMY 45778 ≥99%(HPLC) | 152575-66-1 | 50 | $587 | 2021-12-16 | Buy |
| TRC | B596418 | BMY 45778 | 152575-66-1 | 2.5mg | $175 | 2021-12-16 | Buy |
| ApexBio Technology | B6741 | BMY 45778 | 152575-66-1 | 10mg | $213 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0008616 | BMY 45778 95.00% | 152575-66-1 | 10MG | $709.46 | 2021-12-16 | Buy |
BMY 45778 Chemical Properties,Uses,Production
Uses
BMY 45778 is an agonist for IP receptor to up-regulate the expression of C?/EBPβ and C?/EBPδ.
Definition
ChEBI: BMY 45778 is a bisoxazole. It has a role as a partial prostacyclin agonist.
Biological Activity
Non-prostanoid prostacyclin mimetic that acts as a partial agonist at IP 1 prostacyclin receptors. Potently inhibits platelet aggregation in vitro (IC 50 = 27-35 nM).
Biochem/physiol Actions
BMY 45778 is a non-prostanoid prostacyclin agonist.
References
[1]. seiler sm, brassard cl, federici me, et al. [3-[4-(4,5-diphenyl-2-oxazolyl)-5-oxazolyl]phenoxy]acetic acid (bmy 45778) is a potent non-prostanoid prostacyclin partial agonist: effects on platelet aggregation, adenylyl cyclase, camp levels, protein kinase, and iloprost binding. prostaglandins, 1997, 53(1): 21-35.
[2]. wise h, qian ym, jones rl. a study of prostacyclin mimetics distinguishes neuronal from neutrophil ip receptors. eur j pharmacol, 1995, 278(3): 265-269.
BMY 45778 Preparation Products And Raw materials
Raw materials
Preparation Products
BMY 45778 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4428 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2983 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 3915 | 58 |