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Pyridoxal 5'-phosphate monohydrate

Pyridoxal 5'-phosphate monohydrate
Pyridoxal 5'-phosphate monohydrate structure
CAS No.
41468-25-1
Chemical Name:
Pyridoxal 5'-phosphate monohydrate
Synonyms
PLP;Plp1;ACR1;B116;AOEB116;FLJ32703;5'-phosphate;PRDX 5 human;Pyridoxal 5'CODECARBOXYLASE
CBNumber:
CB6757175
Molecular Formula:
C8H12NO7P
Formula Weight:
265.16
MOL File:
41468-25-1.mol

Pyridoxal 5'-phosphate monohydrate Properties

Melting point:
140-143 °C(lit.)
storage temp. 
2-8°C
form 
Crystalline Powder
color 
Pale yellow
Water Solubility 
5 g/L (20 ºC)
Sensitive 
Light Sensitive
Merck 
14,7979
BRN 
234749
InChIKey
CEEQUQSGVRRXQI-UHFFFAOYSA-N
CAS DataBase Reference
41468-25-1(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  2
RTECS  UV1208000
8-10-23
TSCA  Yes
HS Code  29333990

Pyridoxal 5'-phosphate monohydrate price More Price(49)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P9255 Pyridoxal 5′-phosphate hydrate ≥98% 41468-25-1 1 g $46.3 2021-12-16 Buy
Sigma-Aldrich 82870 Pyridoxal 5′-phosphate monohydrate ≥97.0% (NT) 41468-25-1 1g $57.6 2021-12-16 Buy
Sigma-Aldrich P3657 Pyridoxal 5′-phosphate hydrate powder, BioReagent, suitable for cell culture 41468-25-1 1 g $66.2 2021-12-16 Buy
Sigma-Aldrich P9255 Pyridoxal 5′-phosphate hydrate ≥98% 41468-25-1 5 g $168 2021-12-16 Buy
Sigma-Aldrich 82870 Pyridoxal 5′-phosphate monohydrate ≥97.0% (NT) 41468-25-1 5g $201 2021-12-16 Buy

Pyridoxal 5'-phosphate monohydrate Chemical Properties,Uses,Production

Chemical Properties

Pyridoxal Phosphate Hydrate occurs as a pale yellow-white to light yellow crystalline powder.
It is slightly soluble in water, and practically insoluble in ethanol (99.5).
It dissolves in dilute hydrochloric acid and in sodium hydroxide TS.
The pH of a solution prepared by dissolving 0.1 g of Pyridoxal Phosphate Hydrate in 200 mL of water is between 3.0 and 3.5.
Pyridoxal Phosphate Hydrate is colored to light red by light.

Uses

Pyridoxal 5-phosphate (PLP) (active form of Vitamin B6) is an enzyme prosthetic group that acts as a coenzyme in transamination, decarboxylation and deamination reactions such as the conversion of dopa into dopamine; of glutamate into GABA; of histidine to histamine. PLP works mechanistically through formation of a Schiff-base.

Uses

Active form of Vitamin B-6Pyridoxal-5?-phosphate monohydrate is used to modify the lysyl and valyl residues in proteins. It acts as a coenzyme in transamination reactions and as an inhibitor for purinergic receptors and intracellular. It is involved in decarboxylation and deamination reactions viz. the conversion of dopa into dopamine of glutamate into GABA and histidine to histamine.

Application

Pyridoxal 5′-phosphate (PLP), an active form of vitamin B6/ pyridoxine is the coenzyme of amino acid metabolism.
Pyridoxal 5′-phosphate monohydrate has been used:
as a component in the reaction mixture for ornithine decarboxylase (ODC) activity assay
as a standard to quantify the concentration of pyridoxal 5′-phosphate (PLP) in cerebrospinal fluid (CSF) of children
as a dietary supplement to study its effects on the lethal phenotype of mutant flies.

General Description

Pyridoxal 5′-phosphate (PLP), an active form of vitamin B6/ pyridoxine is the coenzyme of amino acid metabolism.

Biological Activity

Pyridoxine participates in the production of lipid and neurotransmitters. Pyridoxal 5′-phosphate (PLP) serves as a cofactor to stabilize carbanions at Cα of amino acids. Pyridoxine deficiency results in peripheral neuropathy. Absence of PLP leads to neonatal epileptic encephalopathy. PLP acts as a coenzyme in transamination, decarboxylation and deamination reactions such as the conversion of dopa into dopamine; of glutamate into γ aminobutyric acid (GABA); of histidine to histamine. PLP works mechanistically through formation of a Schiff-base.

Biochem/physiol Actions

Pyridoxine participates in the production of lipid and neurotransmitters. Pyridoxal 5′-phosphate (PLP) serves as a cofactor to stabilize carbanions at Cα of amino acids. Pyridoxine deficiency results in peripheral neuropathy. Absence of PLP leads to neonatal epileptic encephalopathy. PLP acts as a coenzyme in transamination, decarboxylation and deamination reactions such as the conversion of dopa into dopamine; of glutamate into γ aminobutyric acid (GABA); of histidine to histamine. PLP works mechanistically through formation of a Schiff-base.

Pyridoxal 5'-phosphate monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products


Pyridoxal 5'-phosphate monohydrate Suppliers

Global( 367)Suppliers
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Jiangsu Qingquan Chemical Co., Ltd.
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SHANDONG ZHI SHANG CHEMICAL CO.LTD
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View Lastest Price from Pyridoxal 5'-phosphate monohydrate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-12-08 Pyridoxal 5-phosphate monohydrate(PLP)
41468-25-1
US $0.00 / g 10g ≥98%(Excellent grade) 2tons Hangzhou Weitai Biological Pharmaceutical Co.,Ltd.
2021-12-03 Pyridoxal 5'-phosphate monohydrate
41468-25-1
US $10.00 / Kg/Bag 1Kg/Bag 99% 20 Tons Hebei Zhanyao Biotechnology Co. Ltd
2021-11-30 Pyridoxal 5'-phosphate monohydrate
41468-25-1
US $318.00 / Kg/Bag 1KG 98% 1T Baoji Guokang Bio-Technology Co., Ltd.

Pyridoxal 5'-phosphate monohydrate Spectrum


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