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3-Amino-5-fluoropyridine

3-Amino-5-fluoropyridine Structure
3-Amino-5-fluoropyridine structure
CAS No.
210169-05-4
Chemical Name:
3-Amino-5-fluoropyridine
Synonyms
5-Fluoropyridin-3-amine;5-Fluoro-3-pyridinamine;3-AMINO-5-FLUOROPYRIDINE;3-PyridinaMine,5-fluoro-;3-Amine-5-fluoro-pyridin;5-Fluoropyridin-3-ylamine;3-AMine-5-fluoro-pyridine;3-Amino-5-fluoropyridine >3-aMino -5-fluorine pyridine;3-AMINO-5-FLUOROPYRIDINE 97%
CBNumber:
CB6767921
Molecular Formula:
C5H5FN2
Molecular Weight:
112.11
MDL Number:
MFCD00234073
MOL File:
210169-05-4.mol
MSDS File:
SDS
Last updated:2023-06-01 19:39:48
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3-Amino-5-fluoropyridine Properties

Melting point 86°C
Boiling point 232.7±20.0 °C(Predicted)
Density 1.257±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form powder to crystal
pka 3.74±0.20(Predicted)
color Light orange to Yellow to Green
CAS DataBase Reference 210169-05-4(CAS DataBase Reference)
FDA UNII T287Q2D5WG

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  20/21/22-36/37/38-22
Safety Statements  26-36-36/37
WGK Germany  3
HazardClass  IRRITANT
HS Code  2933399990
NFPA 704
0
2 0

3-Amino-5-fluoropyridine price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 732176 3-Amino-5-fluoropyridine 210169-05-4 500mg $131 2023-06-20 Buy
TCI Chemical A2753 3-Amino-5-fluoropyridine >97.0%(GC)(T) 210169-05-4 1g $62 2024-03-01 Buy
TCI Chemical A2753 3-Amino-5-fluoropyridine >97.0%(GC)(T) 210169-05-4 5g $211 2024-03-01 Buy
Alfa Aesar H34111 3-Amino-5-fluoropyridine, 98% 210169-05-4 5g $243.65 2024-03-01 Buy
Alfa Aesar H34111 3-Amino-5-fluoropyridine, 98% 210169-05-4 1g $61.1 2021-12-16 Buy
Product number Packaging Price Buy
732176 500mg $131 Buy
A2753 1g $62 Buy
A2753 5g $211 Buy
H34111 5g $243.65 Buy
H34111 1g $61.1 Buy

3-Amino-5-fluoropyridine Chemical Properties,Uses,Production

Chemical Properties

Light yellow Crystal

Uses

3-amino-5-fluoropyridine is an important intermediate mainly used in medicine and organic synthesis. It is used to synthesize Ivosidenib. Ivosidenib is an isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia and cholangiocarcinoma in adults.

Preparation

synthesis of 3-Amino-5-fluoropyridine: A solution of 3-amino-2,4,6-tribromo-5-fluoropyridine (23c) (0.9 g, 2.6 mmol), triethylamine (1.1 cm3, 7.9 mmol), palladium catalyst (0.1 g of 5% Pd-C catalyst) and DCM (15 cm3) was hydrogenated on a Parr apparatus for 18 h. Water (20 cm3) was added and the mixture filtered and extracted into DCM. The DCM solution was dried (MgS04) and evaporated giving 3-amino-5-fluoropyridine (0.3 g, >95% ), m.p. 86 ·c (from DCM) (Found: C, 53.6; H, 4.6; N, 25.0. C5H5FN2 requires C, 53.6; H, 4.5 N, 25.0%);
IR spectrum no. 9; mass spectrum no. 5; nmr spectrum no. 29.

Application

Reactant for:
Preparation of nonpeptide inhibitors of measles virus entry.

3-Amino-5-fluoropyridine synthesis

70-58-6
210169-05-4
Synthesis of 3-Amino-5-fluoropyridine from 5-Fluoronicotinamide

3-Amino-5-fluoropyridine Preparation Products And Raw materials

Raw materials

4-Methylmorpholine Hexane Isoamyl nitrite Ethanol Ammonium formate
Diphenylphosphoryl azide Benzyl alcohol 5-Fluoronicotinic acid Palladium Fluoroboric acid
Diethyl ether 1,2-Dichloroethane 5-Methylpyridin-3-amine Hydrochloric acid Methanol
Carbamic acid, N-(5-fluoro-3-pyridinyl)-, phenylmethyl ester 2,6-DICHLORO-5-FLUORONICOTINOYL CHLORIDE 2,4,6-TRIBROMO-3,5-DIFLUOROPYRIDINE

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Preparation Products

3-Amino-5-fluoropyridine Suppliers

Global( 316)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Hi-Tech Chemistry Corp 		0519-86626038 yuhh@hitechem.com CHINA 811 58
Dongfan Chem. Co., Ltd. 		021-34500607 13391355195 sales@dfanchem.com CHINA 61 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4242 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 6992 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Hi-Tech Chemistry Corp 		58
Dongfan Chem. Co., Ltd. 		55
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Changzhou Ansciep Chemical Co., Ltd. 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Jinan Carbotang Biotech Co.,Ltd. 		58

View Lastest Price from 3-Amino-5-fluoropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-AMINO-5-FLUOROPYRIDINE pictures 2024-04-17 3-AMINO-5-FLUOROPYRIDINE
210169-05-4
 US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
3-Amino-5-fluoropyridine pictures 2023-06-03 3-Amino-5-fluoropyridine
210169-05-4
 US $0.00 / kg 1kg 99% follow your request Changzhou waston chemical technology Co.,Ltd
5-fluoropyridin-3-amine pictures 2022-02-19 5-fluoropyridin-3-amine
210169-05-4
 US $0.00 / KG 1KG 98.7% 100 tons Honest Joy Holdings Limited

3-Amino-5-fluoropyridine Spectrum

3-Amino-5-fluoropyridine(210169-05-4)1HNMR3-Amino-5-fluoropyridine(210169-05-4)FT-IR

210169-05-4(3-Amino-5-fluoropyridine)Related Search:

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4-(DIMETHYLAMINO)-2,3,5,6-TETRAFLUOROPYRIDINE 5-FLUORO-2-HYDROXY-3-NITROPYRIDINE 4-AMINO-3-CHLORO-2,5,6-TRIFLUOROPYRIDINE 4-Amino-2-fluoropyridine97%,4-AMINO-2-FLUOROPYRIDINE 2-Amino-5-fluoropyridine
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3-AMINO-5-FLUOROPYRIDINE 3-Pyridinamine,5-fluoro-(9CI) 3-AMINO-5-FLUOROPYRIDINE 97% 5-Fluoropyridin-3-ylamine 3-Amine-5-fluoro-pyridin 3-AMine-5-fluoro-pyridine 3-PyridinaMine,5-fluoro- 3-aMino -5-fluorine pyridine 5-Fluoro-3-pyridinamine 3-AMINO-5-FLUOROPYRIDINE(RS20014327) 3-Amino-5-fluoropyridine > 3-AMINO-5-FLUOROPYRIDINE ISO 9001：2015 REACH 5-Fluoropyridin-3-amine 210169-05-4 210169-05-4 Fluorine series Building Blocks C5 C5 to C6 Chemical Synthesis Fluorinated Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Heterocyclic Fluorinated Building Blocks Other Fluorinated Heterocycles Pyridine series Pyridines Boronic Acid PYRIDINE AMINEPRIMARY HALIDE