ChemicalBook >> CAS DataBase List >>Hydroxymetronidazole

Hydroxymetronidazole

CAS No.
4812-40-2
Chemical Name:
Hydroxymetronidazole
Synonyms
MNZOH;METRONIDAZOLE-OH;Hydroxy Metronidazo;HYDROXY METRONIDAZOLE;Metronidazole-hydroxy;Metronidazole-OH MNZOH;Metronidazole Impurity H;2-(HydroxyMethyl)-5-nitro-;Metronidazole EP Impurity H;ROXYMETHYL-5-NITROIMIDAZOLE
CBNumber:
CB6772530
Molecular Formula:
C6H9N3O4
Molecular Weight:
187.15
MDL Number:
MFCD01721480
MOL File:
4812-40-2.mol
Last updated:2023-06-08 09:03:04

Hydroxymetronidazole Properties

Melting point 118-121°C
Boiling point 321.89°C (rough estimate)
Density 1.4796 (rough estimate)
refractive index 1.5800 (estimate)
storage temp. -20°C Freezer
solubility DMSO (Sparingly), Methanol (Slightly)
pka 13.28±0.10(Predicted)
color White to Light Beige
FDA UNII 7RUI9488IL

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H319-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Safety Statements  24/25
WGK Germany  3
RTECS  NI5568000
HS Code  29332900
NFPA 704
0
2 0

Hydroxymetronidazole price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 34007 Metronidazole-OH VETRANAL?, analytical standard 4812-40-2 10MG $235 2024-03-01 Buy
Usbiological 014143 Hydroxy Metronidazole 4812-40-2 25mg $446 2021-12-16 Buy
TRC H948395 HydroxyMetronidazole 4812-40-2 250mg $1355 2021-12-16 Buy
American Custom Chemicals Corporation API0005832 HYDROXY METRONIDAZOLE 95.00% 4812-40-2 250MG $1871.1 2021-12-16 Buy
American Custom Chemicals Corporation API0005832 HYDROXY METRONIDAZOLE 95.00% 4812-40-2 25MG $739.2 2021-12-16 Buy
Product number Packaging Price Buy
34007 10MG $235 Buy
014143 25mg $446 Buy
H948395 250mg $1355 Buy
API0005832 250MG $1871.1 Buy
API0005832 25MG $739.2 Buy

Hydroxymetronidazole Chemical Properties,Uses,Production

Description

Hydroxy metronidazole is a metabolite of metronidazole. Metronidazole belongs to the nitroimidazole class of drugs. In agricultural production, it is often used as a drug to expel parasites in animals. After being added to animal feed, metronidazole remains in eggs. Because metronidazole has a variety of toxic and side effects on the human body, especially its potential carcinogenicity and hereditary mutation effects, and metronidazole can be rapidly distributed throughout the body after entering the human body, so the residual metronidazole and its metabolites in eggs inspection is necessary.

Chemical Properties

Off-White Solid

Uses

Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle.

Definition

ChEBI: Metronidazole-OH is a member of imidazoles and a C-nitro compound.

Biological Activity

Hydroxymetronidazole is an active metabolite of the antibiotic metronidazole (Item No. 9002409). It is formed from metronidazole primarily by the cytochrome P450 (CYP) isoform CYP2A6. Hydroxymetronidazole is active against B. fragilis, B. thetaiotaomicron, B. distasonis, and B. ovatus (MICs = 1, 2, 1, and 2 μg/ml, respectively). It has been found in pork and porcine plasma.

1016-40-6
4812-40-2
Synthesis of Hydroxymetronidazole from 2-Methyl-5-nitro-1H-imidazole-1-acetic acid ethyl ester

Hydroxymetronidazole Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 81)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10326 58
Hong Kong Tiansheng New Material Trading Co., Ltd
+8617320695765 zxx@hktiansheng.com China 981 58
sgtlifesciences pvt ltd
+8617013299288 dj@sgtlifesciences.com China 12382 58
Hebei baicao biology science and technology co., ltd
+86-19131911055 +8617824879454 zhang@hbbocao.com China 1035 58
China National Standard Pharmaceutical Corporation Limited
+8615391658522 overseasales@yongstandards.com China 11927 58
Jiangsu Zhixinting Technology Co., Ltd 18221391031 1204449826@qq.com China 504 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50

View Lastest Price from Hydroxymetronidazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Hydroxymetronidazole pictures 2023-02-13 Hydroxymetronidazole
4812-40-2
US $9.00 / kg 1kg 99% 50MT Hebei baicao biology science and technology co., ltd
Hydroxymetronidazole pictures 2022-02-25 Hydroxymetronidazole
4812-40-2
US $1.11 / KG 1KG 99% 10tons Hong Kong Tiansheng New Material Trading Co., Ltd
2-hydroxymethyl-5-nitro-imidazole-1-ethano MNZOH Metronidazole-hydroxy METRONIDAZOLE-OH 1-(2-Hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole, Hydroxymetronidazole, MNZOH 4-Hydroxy-2-methyl-5-nitro-1H-imidazole-1-ethanol Metronidazole-OH,1-(2-Hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole, Hydroxymetronidazole, MNZOH 1-(2-HYDROXYETHYL)-2-HYDROXYMETHYL-5-NITROIMIDAZOLE HYDROXY METRONIDAZOLE 2-(HydroxyMethyl)-5-nitro- 1H-IMidazole-1-ethanol, 2-(hydroxyMethyl)-5-nitro- Metronidazole-OH MNZOH MNZOH, Hydroxy metronidazole Solution, 100ppm Metronidazole-hydroxy solution,1000ppm solution,100ppm Metronidazole-hydroxy solution,100ppm Metronidazole Impurity H 1-(2-Hydroxyethyl)-2-hydroxymethyl- Metronidazole EP Impurity H ROXYMETHYL-5-NITROIMIDAZOLE Hydroxy Metronidazole D2Q: What is Hydroxy Metronidazole D2 Q: What is the CAS Number of Hydroxy Metronidazole D2 Q: What is the storage condition of Hydroxy Metronidazole D2 Q: What are the applications of Hydroxy Metronidazole D2 Hydroxy MetronidazoleQ: What is Hydroxy Metronidazole Q: What is the CAS Number of Hydroxy Metronidazole Q: What is the storage condition of Hydroxy Metronidazole Q: What are the applications of Hydroxy Metronidazole Hydroxy Metronidazo 1-(2-Hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole (Hydroxy 4812-40-2 Pharmaceuticals Heterocycles Intermediates & Fine Chemicals Metabolites & Impurities