GITOXIGENIN
- CAS No.
- 545-26-6
- Chemical Name:
- GITOXIGENIN
- Synonyms
- GITOXIGENIN;Gitoxygenin;Gitoxigenin,98%;Digoxin Impurity 13;16β-hydroxydigitoxigenin;16BETA-HYDROXYDIGITOXIGENIN;5β,20(22)-Cardenolide-3β,14,16β-triol;3-beta,14,16-trioxycarden-(20:22)-olid;3-beta,14,16-trioxy-digen-(20:22)-olid;cardogenen-(20:22)-triol-(3-beta,14,16)
- CBNumber:
- CB6780665
- Molecular Formula:
- C23H34O5
- Molecular Weight:
- 390.51
- MDL Number:
- MFCD00021174
- MOL File:
- 545-26-6.mol
| Product description | Number | Pack Size | Price |
| Gitoxigenin | G388725 | 5mg | $1890 |
| GITOXIGENIN 95.00% | SHG0000396 | 10MG | $582.97 |
| More product size | |||
| Melting point | ~230 °C |
|---|---|
| Boiling point | 435.71°C (rough estimate) |
| Density | 1.0639 (rough estimate) |
| refractive index | 1.6120 (estimate) |
| storage temp. | −20°C |
| pka | 14.56±0.70(Predicted) |
| Merck | 13,4445 |
| FDA UNII | G36K2H8SME |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H311-H301-H331 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P280-P302+P352-P312-P322-P361-P363-P405-P501-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 23/24/25 | |||||||||
| Safety Statements | 36/37/39-45 | |||||||||
| RIDADR | UN 1544 6.1/PG 1 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | FH5391000 | |||||||||
| F | 10 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| NFPA 704 |
|
GITOXIGENIN price More Price(2)
GITOXIGENIN Chemical Properties,Uses,Production
Chemical Properties
light yellow flakes
Uses
Gitoxigenin is a related compound of Digitoxigenin, which has been used in a study to assess its stereochemical effects in cancer cytotoxicity. Digitoxigenin has also been used in a study to investigate the advantage of gold(I)-catalyzed glycosidation of glycosyl o-alkyl benzoates to assemble digitoxin.
Definition
ChEBI: Gitoxigenin is a 3beta-hydroxy steroid, a 14beta-hydroxy steroid and a 16beta-hydroxy steroid. It derives from a hydride of a 5beta-cardanolide.
Biochem/physiol Actions
Structure-activity relationships for 16β-substituted digitoxigenins as inhibitors of Na+/K+ ATPases.
Purification Methods
Recrystallisation of gitoxigenin from aqueous EtOH produces plates of the sesquihydrate which dehydrate on drying at 100o in vacuo. It also recrystallises from Me2CO/MeOH and from EtOAc (the crystals contain 1 mol of EtOAc) with [] D +24.8o (c 1, dioxane). It has UV with max at 310, 485 and 520nm in 96% H2SO4. On heating with ethanolic HCl it yields digitaligenin with loss of H2O. [Smith J Chem Soc 23 1931, Beilstein 8 IV 2456.]
GITOXIGENIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53899 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40228 | 62 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3988 | 66 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 18080489829@163.com | China | 8314 | 60 |
| Shenzhen Botel Biotechnology Co. Ltd. | 13316949107 13316968096 | 1979313431@qq.com | China | 9562 | 58 |
| Hubei Xinyang Medical Technology Co., Ltd | 15347293736 | 2853117764@yongstandards.com | China | 10000 | 58 |
| QUALITY CONTROL SOLUTIONS LTD. | +86-0755-66853366 +86-13670046396 | export03@qcsrm.com | China | 24342 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 029-029-81120477 17792793610 | 1033@dideu.com | China | 9997 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 13308200041 | 2851167782@qq.com | China | 11143 | 58 |
| Santa Cruz Biotechnology Inc | 021-60936350 | scbt@scbt.com | China | 6594 | 58 |
