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Crisaborole intermediate
- CAS No.
- 1187188-60-8
- Chemical Name:
- Crisaborole intermediate
- Synonyms
- Crisaborole Impurity 28;Crisaborole Impurity 37;Crisaborole Impurity 59;5-(4-(hydroxymethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol;5-(4-(Hydroxylmethyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol;Benzenemethanol, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
- CBNumber:
- CB68131269
- Molecular Formula:
- C14H13BO4
- Molecular Weight:
- 256.06
- MDL Number:
- MOL File:
- 1187188-60-8.mol
Last updated:2024-04-08 13:48:25
| Boiling point | 432.1±55.0 °C(Predicted) |
|---|---|
| Density | 1.33±0.1 g/cm3(Predicted) |
| pka | 7.05±0.20(Predicted) |
| FDA UNII | XF46UA9G2H |
Crisaborole intermediate Chemical Properties,Uses,Production
Uses
5-(4-(Hydroxyl Methyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol is an impurity for Crisaborole(H947928). Crisaborole is a series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-?(4-?Cyanophenoxy)?-?2,?3-?dihydro-?1-?hydroxy-?2,?1-?benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent.
Crisaborole intermediate Preparation Products And Raw materials
Raw materials
Preparation Products
Crisaborole intermediate Suppliers
Global( 23)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Shenzhen Excellent Biomedical Technology Co.,Ltd. | +86-0755-26050679 +86-15915472436 | sale@ex-biotech.cn | China | 1031 | 58 |
| ShenZhen H&D Pharmaceutical Technology Co., LTD | +8613627253706 | sale@hdimpurity.com | China | 1501 | 58 |
| Beijing Comparison Pharmaceutical Technology Co., Ltd | 010-52878169 15701683040 | sales@bjcomparison.com | China | 4671 | 58 |
| ChemStrong Scientific Co.,Ltd | 0755-66853366 13670046396 | sales@chem-strong.com | China | 17982 | 56 |
| Hubei Yangxin Medical Technology Co., Ltd. | 15374522761 | 3003392093@qq.com | China | 7851 | 55 |
| TOSUN PHARM | 13326451905 | 2881290884@qq.com | China | 7399 | 58 |
| Yangzhou Changhua Biotechnology Co., Ltd. | 13815846020; 13815846020 | 438399391@qq.com | China | 851 | 58 |
| Shenzhen ruikai de biotechnology co., ltd. | 0755-61348847 17820674378 | 2682116078@qq.com | China | 7844 | 58 |
| Wuxi Helen Biotechnology Co., Ltd., | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 14092 | 58 |
View Lastest Price from Crisaborole intermediate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-08 | Crisaborole Impurity 28
1187188-60-8
|
US $0.00 / mg | 10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD |
-
- Crisaborole Impurity 28
1187188-60-8
- US $0.00 / mg
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
5-(4-(hydroxymethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol
5-(4-(Hydroxylmethyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol
Crisaborole Impurity 59
Crisaborole Impurity 37
Crisaborole Impurity 28
Benzenemethanol, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
1187188-60-8