2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE
![2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE Structure](CAS/GIF/41179-33-3.gif)
- CAS No.
- 41179-33-3
- Chemical Name:
- 2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE
- Synonyms
- CMPD-1;CMD1;SRA1;MK2a Inhibitor;CMPD-1 (CMPD 1;Steroid receptor RNA activator 1;ANTI-SOX9 antibody produced in mouse;MK2a Inhibitor - CAS 41179-33-3 - Calbiochem;ANTI-SRA1 (C-TERM) antibody produced in rabbit;Monoclonal Anti-SOX9 antibody produced in mouse
- CBNumber:
- CB6840374
- Molecular Formula:
- C22H20FNO2
- Molecular Weight:
- 349.4
- MDL Number:
- MFCD08703098
- MOL File:
- 41179-33-3.mol
| Melting point | 128-130 °C |
|---|---|
| Boiling point | 585.0±50.0 °C(Predicted) |
| Density | 1.229±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| form | Pale yellow solid |
| pka | 10.11±0.26(Predicted) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | AMAB90795 | Monoclonal Anti-SOX9 antibody produced in mouse Prestige Antibodies? Powered by Atlas Antibodies, clone CL0639, purified immunoglobulin, buffered aqueous glycerol solution | 41179-33-3 | 25μL | $294 | 2024-03-01 | Buy |
| Sigma-Aldrich | WH0006662M2 | Monoclonal Anti-SOX9 antibody produced in mouse clone 3C10, purified immunoglobulin, buffered aqueous solution | 41179-33-3 | 100μG | $524 | 2024-03-01 | Buy |
| Sigma-Aldrich | AMAB90795 | Monoclonal Anti-SOX9 antibody produced in mouse Prestige Antibodies? Powered by Atlas Antibodies, clone CL0639, purified immunoglobulin, buffered aqueous glycerol solution | 41179-33-3 | 100μL | $514 | 2024-03-01 | Buy |
| Sigma-Aldrich | 475863 | MK2a Inhibitor - CAS 41179-33-3 - Calbiochem | 41179-33-3 | 5mg | $318 | 2024-03-01 | Buy |
| Cayman Chemical | 17325 | MK2a Inhibitor | 41179-33-3 | 5mg | $116 | 2024-03-01 | Buy |
2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE Chemical Properties,Uses,Production
Uses
Monoclonal Anti-SOX9 antibody produced in mouse has been used in immunofluorescence.
Uses
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
Definition
ChEBI: 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide is a member of biphenyls.
General Description
Sex determining region Y box 9 (Sox9) is a transcription protein, that belongs to the high-mobility-group box class DNA-binding proteins. It is located on human chromosome 17q24.
Biological Activity
Non-ATP-competitive, selective inhibitor of p38 α -mediated MK2a (mitogen-activated protein kinase-activated protein kinase 2a) phosphorylation (apparent K i = 330 nM). Does not inhibit p38 α -mediated phosphorylation of the two other known p38 substrates, MBP and ATF-2.
Biochem/physiol Actions
Sex determining region Y box 9 (Sox9) participates in the human development processes. It helps to maintain the pluripotent cells at the time of pancreatic organogenesis. In adult tissues, Sox9 modulates stem and progenitor cells. Haploinsufficiency of Sox9 results in campomelic dysplasia (CD), a disease characterized by bowed femurs and tibiae, hypoplastic scapulae, 11 pairs of ribs, pelvic malformations, Robin sequence and clubbed feet.
storage
Store at RT
2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| ATK CHEMICAL COMPANY LIMITED | 3429815786 13301662590 | sales@atkchemical.com | China | 10007 | 55 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3444 | 55 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |