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Trifluoroacetic anhydride

Trifluoroacetic anhydride
Trifluoroacetic anhydride structure
CAS No.
407-25-0
Chemical Name:
Trifluoroacetic anhydride
Synonyms
TFAA;trifluoroacetic;Trifluoroacetic anhy;trimethylamine (TMA);TRIFLUOROACETO ANHYDRIDE;TIFLUOROACETIC ANHYDRIDE;RIFLUOROACETIC ANHYDRIDE;TRIFLUORACETIC ANHYDRIDE;perfluoroaceticanhydride;Perfluoracetic anhydride
CBNumber:
CB6853606
Molecular Formula:
C4F6O3
Formula Weight:
210.03
MOL File:
407-25-0.mol

Trifluoroacetic anhydride Properties

Melting point:
-63.5 °C
Boiling point:
39.5-40 °C(lit.)
Density 
1.511 g/mL at 20 °C(lit.)
vapor pressure 
6.28 psi ( 20 °C)
refractive index 
n20/D 1.3(lit.)
Flash point:
-26 °C
storage temp. 
2-8°C
solubility 
Miscible with benzene, dichloromethane, diethyl ether, dimethylformamide, terahydrofuran and acetonitrile.
form 
Liquid
Specific Gravity
1.487
color 
Clear
Water Solubility 
Hydrolysis
Sensitive 
Moisture Sensitive
BRN 
746197
Stability:
Stable, but moisture sensitive. Reacts with water to liberate hydrogen (flammable!). Incompatible with water, strong oxidizing agents.
CAS DataBase Reference
407-25-0(CAS DataBase Reference)
NIST Chemistry Reference
Acetic acid, trifluoro-, anhydride(407-25-0)
EPA Substance Registry System
Acetic acid, trifluoro-, anhydride(407-25-0)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H318-H402-H314-H332-H412
Precautionary statements  P280-P305+P351+P338-P310-P273-P260h-P301+P330+P331-P303+P361+P353-P405-P501a
Hazard Codes  C,T
Risk Statements  14-20-35-52/53-34-23/24/25
Safety Statements  26-36/37/39-43-45-61-9-8-28A-27
RIDADR  UN 3265 8/PG 1
WGK Germany  2
RTECS  AJ9800000
3-10
Hazard Note  Corrosive/Moisture Sensitive
TSCA  T
HazardClass  8
PackingGroup  I
HS Code  29159080

Trifluoroacetic anhydride price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 106232 Trifluoroacetic anhydride ReagentPlus , ≥99% 407-25-0 10x1g $177 2018-11-13 Buy
Sigma-Aldrich 106232 Trifluoroacetic anhydride ReagentPlus , ≥99% 407-25-0 3kg $1100 2018-11-13 Buy
TCI Chemical T0433 Trifluoroacetic Anhydride >98.0%(GC) 407-25-0 20mL $29 2018-11-22 Buy
TCI Chemical T0433 Trifluoroacetic Anhydride >98.0%(GC) 407-25-0 100mL $94 2018-11-22 Buy
Alfa Aesar A13614 Trifluoroacetic anhydride 99+% 407-25-0 25g $20.6 2018-11-20 Buy

Trifluoroacetic anhydride Chemical Properties,Uses,Production

Chemical Properties

Clear, colorless liquid

Uses

Used as analytical reagents, solvents, catalysts, dehydration condensing agent, protection agent of trifluoroacetylation of carboxyl and amino; used as Intermediate of fluorine fine chemicals, pharmaceutical, agrochemical.

Purification Methods

Purification by distilling over KMnO4, as for the acid above, is EXTREMELY DANGEROUS due to the possiblility of EXPLOSION. It is best purified by distilling from P2O5 slowly, and collecting the fraction boiling at 39.5o. Store it in a dry atmosphere. Highly TOXIC vapour and attacks skin, work in an efficient fume hood. [Beilstein 2 IV 469.]

Trifluoroacetic anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

1-[4-(TRIFLUOROMETHYL)PYRIMID-2-YL]PIPERAZINE 2-CYANO-4-PYRIDINE CARBOXYLIC ACID 2-Hydroxy-4-(trifluoromethyl)pyrimidine 2-Hydroxymethyl-5-bromopyridine 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carbonitrile 2-Chloro-4-(trifluoromethyl)pyrimidine [BIS(TRIFLUOROACETOXY)IODO]PENTAFLUOROBENZENE 6-Aminobenzothiazole 2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINIC ACID 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxamide (2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)methanamine 2,6-DICHLORO-4-ISOCYANATOPYRIDINE Ethyl 2-(4-hydroxypiperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate Ethyl 2-(4-(ethoxycarbonyl)piperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate Ethyl 2-(4-(hydroxymethyl)piperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate 3-(Trifluoromethyl)pyrazole 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE Chlorfenapyr (2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)methanol 3-(Trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine 4-CHLORO-ALPHA-[METHYL(TRIFLUOROACETYL)AMINO]-BENZENEACETIC ACID 2-(METHYLTHIO)-4-(TRIFLUOROMETHYL)PYRIMIDINE tert-Butyl 4-[4-(trifluoromethyl)pyrimidin-2-yl]piperazine-1-carboxylate ,97% 3-Nitroisonicotinic acid Ethyl 2-(4-methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 5-Iodo-2,4-dimethoxypyrimidine N10-(TRIFLUOROACETYL)PTEROIC ACID 3-Amino-4-nitrobenzitrifluoride 2-(TRIFLUOROACETYL)THIOPHENE 2-BROMO-4-(TRIFLUOROMETHYL)PYRIMIDINE 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carbaldehyde Epirubicin 2-(Bromomethyl)-6-methylpyridine 5-Bromopyridine-2-carbaldehyde ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylic acid 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-amine 3-CHLORO-5-NITROPYRIDINE [Bis(trifluoroacetoxy)iodo]benzene

Trifluoroacetic anhydride Suppliers

Global( 336)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21714 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1365 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 fandachem@gmail.com CHINA 2883 55
Fluoropharm Co., Ltd.
+8613336034509
sales@fluoropharm.com CHINA 735 60
Zjartschem
+86-571-8723 8903 jocelynpan@zjarts.com
+86-571-87063838 jocelynpan@zjarts.com CHINA 997 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30002 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23980 58

View Lastest Price from Trifluoroacetic anhydride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-06 Trifluoroacetic anhydride
407-25-0
US $1.00 / KG 1KG 98% 1 career henan chemical co

Trifluoroacetic anhydride Spectrum


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