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Atorvastatin (calcium salt hydrate)

CAS No.
357164-38-6
Chemical Name:
Atorvastatin (calcium salt hydrate)
Synonyms
Atorvastatin (calcium salt hydrate);2-(4-fluorophenyl)-βR,δR-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, hemicalcium salt, hydrate
CBNumber:
CB68570987
Molecular Formula:
C33H39CaFN2O6
Molecular Weight:
618.76
MDL Number:
MOL File:
357164-38-6.mol
Last updated:2023-05-21 10:59:17

Atorvastatin (calcium salt hydrate) Properties

storage temp. Store at -20°C
solubility DMF: 25 mg/ml,DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml,DMSO: 15 mg/ml,Ethanol: 0.5 mg/ml
form A crystalline solid

Atorvastatin (calcium salt hydrate) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10493 Atorvastatin (calcium salt hydrate) ≥98% 357164-38-6 5mg $32 2024-03-01 Buy
Cayman Chemical 10493 Atorvastatin (calcium salt hydrate) ≥98% 357164-38-6 10mg $44 2024-03-01 Buy
Cayman Chemical 10493 Atorvastatin (calcium salt hydrate) ≥98% 357164-38-6 25mg $63 2024-03-01 Buy
Cayman Chemical 10493 Atorvastatin(calciumsalthydrate) ≥98% 357164-38-6 50mg $109 2024-03-01 Buy
Product number Packaging Price Buy
10493 5mg $32 Buy
10493 10mg $44 Buy
10493 25mg $63 Buy
10493 50mg $109 Buy

Atorvastatin (calcium salt hydrate) Chemical Properties,Uses,Production

Biological Activity

Atorvastatin is an inhibitor of HMG-CoA reductase, the rate-limiting enzyme in the mevalonate pathway of cholesterol synthesis, that has IC50 values of 73, 102, and 0.6 nM for HepG2 cells, human fibroblasts, and rat hepatocytes, respectively.1 Formulations containing atorvastatin have been used in the treatment of hypercholesterolemia and certain dyslipidemias.

References

1.Shaw, M.K., Newton, R.S., Sliskovic, D.R., et al.Hep-G2 cells and primary rat hepatocytes differ in their response to inhibitors of HMG-CoA reductaseBiochem. Biophys. Res. Commun.170(2)726-734(1990)

Atorvastatin (calcium salt hydrate) Preparation Products And Raw materials

Raw materials

Preparation Products

Atorvastatin (calcium salt hydrate) Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Atorvastatin (calcium salt hydrate) 2-(4-fluorophenyl)-βR,δR-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, hemicalcium salt, hydrate 357164-38-6