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Etofenamate

CAS No.
30544-47-9
Chemical Name:
Etofenamate
Synonyms
ReuMon;TV-485;Rheumon;TVX-485;CS-1431;Bayrogel;Etofenate;Etofenamate;TrauMon Gel;Ethofenamate
CBNumber:
CB6883241
Molecular Formula:
C18H18F3NO4
Molecular Weight:
369.33
MDL Number:
MFCD00242806
MOL File:
30544-47-9.mol
MSDS File:
SDS
Last updated:2023-06-08 09:02:53

Etofenamate Properties

Melting point 25°C
Boiling point bp.001 130-135°
Density 1.2866 (estimate)
refractive index nD25 1.564
storage temp. Sealed in dry,2-8°C
solubility Practically insoluble in water, miscible with ethanol (96 per cent) and with ethyl acetate.
pka 14.32±0.10(Predicted)
Stability Light Sensitive
FDA UNII KZF0XM66JC
ATC code M02AA06

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS09
Signal word  Danger
Hazard statements  H301-H410
Precautionary statements  P301+P330+P331+P310
RIDADR  UN2810 - class 6.1 - PG 3 - EHS - Toxic, liquids, organic, n.o.s., HI: all
Toxicity LD50 in male, female rats (mg/kg): 292, 470 orally; 140, 226 i.v.; 373, 397 i.p.; 643, 568 s.c. (Jacobi)
NFPA 704
0
2 0

Etofenamate price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E2499901 Etofenamate for peak identification European Pharmacopoeia (EP) Reference Standard 30544-47-9 e2499901 $153 2024-03-01 Buy
Sigma-Aldrich E2499900 Etofenamate European Pharmacopoeia (EP) Reference Standard 30544-47-9 e2499900 $150 2024-03-01 Buy
Cayman Chemical 23674 Etofenamate ≥98% 30544-47-9 50mg $89 2024-03-01 Buy
Cayman Chemical 23674 Etofenamate ≥98% 30544-47-9 100mg $141 2024-03-01 Buy
Cayman Chemical 23674 Etofenamate ≥98% 30544-47-9 250mg $264 2024-03-01 Buy
Product number Packaging Price Buy
E2499901 e2499901 $153 Buy
E2499900 e2499900 $150 Buy
23674 50mg $89 Buy
23674 100mg $141 Buy
23674 250mg $264 Buy

Etofenamate Chemical Properties,Uses,Production

Chemical Properties

Light Yellow Oil

Originator

Rheumon,Troponwerke,W. Germany,1977

Uses

As a histamine H1 -receptor antagonist, Etofenamate can be used as anti-inflammatory;cyclooxygenase inhibitor and medication used to alleviate joint and muscle pain.

Definition

ChEBI: 2-[3-(trifluoromethyl)anilino]benzoic acid 2-(2-hydroxyethoxy)ethyl ester is a benzoate ester.

Manufacturing Process

16.0 g (0.05 mol) of the potassium salt of N-(3-trifluoromethylphenyl)- anthranilic acid are dissolved in 60 ml of dimethylformamide and heated to 110°C, and 6.2 g (0.05 mol) of 2-(2-chloroethoxy)-ethanol are slowly added. The reaction mixture is then heated to boiling for 2 hours. The precipitated potassium chloride is filtered off and the solvent is removed by evaporation. The residue is separated over a column with 400 g of silica gel (particle size 0.05 to 0.2 mm), using a 1:1 mixture of cyclohexane and glacial acetic acid as eluting agent. 16.0 g of the 2-(2-hydroxyethoxy)-ethyl ester of N-(3- trifluoromethylphenyl)-anthranilic acid are obtained in the form of a pale yellow oil which does not crystallize and cannot be distilled.

Therapeutic Function

Antiinflammatory

Etofenamate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 144)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569265 +86-18612256290 1056@dideu.com China 3683 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17367 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29322 58
AFINE CHEMICALS LIMITED
0571-85134551 info@afinechem.com CHINA 15377 58

View Lastest Price from Etofenamate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Etofenamate pictures 2021-07-20 Etofenamate
30544-47-9
US $1.00-1.00 / KG 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd
Etofenamate USP/EP/BP pictures 2021-06-10 Etofenamate USP/EP/BP
30544-47-9
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
Etofenamate pictures 2019-09-04 Etofenamate
30544-47-9
US $5.00 / KG 1KG 99% 1ton Career Henan Chemical Co
  • Etofenamate pictures
  • Etofenamate
    30544-47-9
  • US $1.00-1.00 / KG
  • 99%
  • Shaanxi Dideu Medichem Co. Ltd
  • Etofenamate pictures
  • Etofenamate
    30544-47-9
  • US $5.00 / KG
  • 99%
  • Career Henan Chemical Co

Etofenamate Spectrum

EtofenamateEtofenamate 2-(2-hydroxyaethoxy)aethylester der flutenaminsaeure 2-(2-hydroxyethoxy)ethyl-n-(alpha,alpha,alpha-trifluoro-m-tolyl)anthrani late Benzoic acid, 2[[3-(trifluoromethyl)phenyl]amino]-2-(hydroxyethoxy)ethyl ester n-(alpha,alpha,alpha-trifluoro-m-tolyl)-anthranilic acid 2-(2-hydroxyethoxy) 2-(2-Hydroxyethoxy)ethyl 2-[3-(trifluoromethyl)anilino]benzoate Ethofenamate Rheumon Etofenamate 2-(2-Hydroxyethoxy)ethyl FufenaMate 2-[[3-(TrifluoroMethyl)phenyl]aMino]benzoic Acid 2-(2-Hydroxyethoxy)ethyl Ester Bayrogel ReuMon TrauMon Gel 2-(2-hydroxyethoxy)ethyl 2-((3-(trifluoroMethyl)phenyl)aMino)benzoate EtofenaMate,TV-485 TV-485 TVX-485 Etofenamate, >=98% CS-1431 Etofenamate CRS Etofenamate for peak identification CRS Benzoic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-, 2-(2-hydroxyethoxy)ethyl ester Etofenamate USP/EP/BP Etofenate 30544-47-9 Inhibitors Amines Aromatics Intermediates & Fine Chemicals Pharmaceuticals