2-Bromo-3',4'-(methylenedioxy)propiophenone
- CAS No.
- 52190-28-0
- Chemical Name:
- 2-Bromo-3',4'-(methylenedioxy)propiophenone
- Synonyms
- Bromo-3′ , 4′ - (methylenedioxy);3',4'-Methylenedioxy-α-broMopropiophenone;3',4'-Methylenedioxy-α-broMopropiophenone;2-Bromo-3',4'-(methylenedioxy)propiophenone;1-(1,3-benzodioxol-5-yl)-2-bromopropan-1-one;1-(1,3-Benzodioxol-5-yl)-2-broMo-1-propanone;1-Propanone, 1-(1,3-benzodioxol-5-yl)-2-bromo-;1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one;Name 2-Bromo-3',4'-(methylenedioxy)propiophenone;Ascorbyl Pa1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-onelmitate
- CBNumber:
- CB6966513
- Molecular Formula:
- C10H9BrO3
- Molecular Weight:
- 257.08
- MDL Number:
- MFCD12403547
- MOL File:
- 52190-28-0.mol
- MSDS File:
- SDS
| Boiling point | 345.7±42.0 °C(Predicted) |
|---|---|
| Density | 1.584±0.06 g/cm3(Predicted) |
| solubility | Chloroform: Soluble; DMSO: 1 mg/mL*; Ethanol: 1 mg/mL |
| form | A crystalline solid |
| InChI | InChI=1S/C10H9BrO3/c1-6(11)10(12)7-2-3-8-9(4-7)14-5-13-8/h2-4,6H,5H2,1H3 |
| InChIKey | NTPQGLLTGPTOAA-UHFFFAOYSA-N |
| SMILES | C(C1=CC=C2OCOC2=C1)(=O)C(Br)C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P264-P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338+P310-P363-P405-P501 |
2-Bromo-3',4'-(methylenedioxy)propiophenone price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | FB19106 | 2-Bromo-3',4'-(methylenedioxy)propiophenone | 52190-28-0 | 50mg | $140 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB19106 | 2-Bromo-3',4'-(methylenedioxy)propiophenone | 52190-28-0 | 100mg | $255 | 2021-12-16 | Buy |
| AK Scientific | 7783CR | 1-(Benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one | 52190-28-0 | 100mg | $394 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB19106 | 2-Bromo-3',4'-(methylenedioxy)propiophenone | 52190-28-0 | 250mg | $462.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0370762 | 1-(BENZO[D][1,3]DIOXOL-5-YL)-2-BROMOPROPAN-1-ONE 95.00% | 52190-28-0 | 5MG | $505.08 | 2021-12-16 | Buy |
2-Bromo-3',4'-(methylenedioxy)propiophenone Chemical Properties,Uses,Production
Chemical Properties
Pale Yellow Solid
Uses
1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one (2-Bromo-3',4'-(methylenedioxy)propiophenone) can be used in the preparation of antifungal agents and MDMA analogs.
Application
2-Bromo-3',4'-(methylenedioxy)propiophenone, also known as 4′-(methylenedioxy)propiophenone, is an analytical reference standard categorized as a precursor in the synthesis of cathinones. This product is intended for research and forensic applications.
Synthesis
Bromine (10.0 mmol) was added to a solution of the ketone (10.0 mmol) in Et2O (25 mL). The solution was stirred for 30 min (until the color of the solution changed from red to light-yellow). Then, the reaction was quenched with water (10 mL), and the mixture was diluted with Et2O (25 mL). The organic layer was washed with a saturated solution of aqueous NaHCO3 (30 mL), a saturated solution of aqueous Na2S2O3 (30 mL), and brine (30 mL), and then it was dried over MgSO4, filtered, and concentrated. The α-bromoketone was purified by flash chromatography on silica gel. 2-Bromo-3',4'-(methylenedioxy)propiophenone [52190-28-0]. This compound was prepared according to the General Procedure from 3,4-methylenedioxypropiophenone (1.78 g, 10.0 mmol). The product was obtained as a white solid (eluted with 50% CH2Cl2 in hexanes; 2.13 g, 82% yield). 1H NMR (CDCl3, 500 MHz) δ 7.64 (d, J= 8.0 Hz, 1H), 7.49 (s, 1H), 6.87 (d, J= 8.0 Hz, 1H), 6.07 (s, 2H), 5.21 (q, J= 7.0 Hz, 1H), 1.88 (d, J= 7.0 Hz, 3H).![1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one synthesis](/NewsImg/2023-05-08/6381915544832604198489645.png "1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one synthesis")
2-Bromo-3',4'-(methylenedioxy)propiophenone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dorne Chemical Technology co. LTD | +86-13583358881 +86-18560316533 | Ethan@dornechem.com | China | 294 | 58 |
| Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3582 | 58 |
| Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 | Sara@xmwonderfulbio.com | China | 305 | 58 |
| Wuhan Ruichi Technology Co., Ltd | +8613545065237 | admin@whrchem.com | China | 164 | 58 |
| Shandong Hanjiang Chemical Co., Ltd | +86-0533-2066820 +8618369939125 | hanson@sdhanjiang.com | China | 1527 | 58 |
| Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 436 | 58 |
| Anhui Yiao New Material Technology Co., Ltd | +86-199-55145978 +8619955145978 | sales8@anhuiyiao.com | China | 253 | 58 |
| Anhui Zhongda Biotechnology Co., Ltd | +8619956560829 | justine@zhongda-biotech.com | China | 300 | 58 |
| Anhui Zhongda Biotechnology Co., Ltd | +8615689548120 | linda@zhongda-biotech.com | China | 204 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
View Lastest Price from 2-Bromo-3',4'-(methylenedioxy)propiophenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-26 | 2-Bromo-3',4'-(methylenedioxy)propiophenone
52190-28-0
|
US $1.00-1.00 / kg | 1kg | 99% | 100kg | Dorne Chemical Technology co. LTD | |
![1-(benzo[d][1,3]dioxol-5-yl)- 2-bromopropan-1-one pictures](/ProductImageEN/2024-03/Small/6f42d88d-3849-417f-b920-201de733a523.jpg) |
2024-04-26 | 1-(benzo[d][1,3]dioxol-5-yl)- 2-bromopropan-1-one
52190-28-0
|
US $0.00 / G | 1G | 99% | 20 | CONTIDE BIOTECH CO.,LTD | |
![1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one pictures](/ProductImageEN/2022-07/Small/1274ab9f-95bc-4268-a83b-95a059d98630.jpg) |
2024-04-25 | 1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one
52190-28-0
|
US $200.00-165.00 / KG | 1KG | 99.8% | 20 tons | Hong Kong Excellence Biotechnology Co., Ltd. |
-
- 2-Bromo-3',4'-(methylenedioxy)propiophenone
52190-28-0
- US $1.00-1.00 / kg
- 99%
- Dorne Chemical Technology co. LTD
-
- 1-(benzo[d][1,3]dioxol-5-yl)- 2-bromopropan-1-one
52190-28-0
- US $0.00 / G
- 99%
- CONTIDE BIOTECH CO.,LTD
-
- 1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one
52190-28-0
- US $200.00-165.00 / KG
- 99.8%
- Hong Kong Excellence Biotechnology Co., Ltd.