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2-Bromo-3',4'-(methylenedioxy)propiophenone

2-Bromo-3',4'-(methylenedioxy)propiophenone Structure
2-Bromo-3',4'-(methylenedioxy)propiophenone structure
CAS No.
52190-28-0
Chemical Name:
2-Bromo-3',4'-(methylenedioxy)propiophenone
Synonyms
Bromo-3′ , 4′ - (methylenedioxy);3',4'-Methylenedioxy-α-broMopropiophenone;2-Bromo-3',4'-(methylenedioxy)propiophenone;1-(1,3-benzodioxol-5-yl)-2-bromopropan-1-one;1-(1,3-Benzodioxol-5-yl)-2-broMo-1-propanone;1-Propanone, 1-(1,3-benzodioxol-5-yl)-2-bromo-;1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one;Name 2-Bromo-3',4'-(methylenedioxy)propiophenone;1-(Benzo [d][1, 3] dioxacyclopentene-5-yl) -2-bromoprop-1-ketone;Ascorbyl Pa1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-onelmitate
CBNumber:
CB6966513
Molecular Formula:
C10H9BrO3
Molecular Weight:
257.08
MDL Number:
MFCD12403547
MOL File:
52190-28-0.mol
MSDS File:
SDS
Last updated:2026-03-11 10:40:40
Product description Number Pack Size Price
2-Bromo-3',4'-(methylenedioxy)propiophenone FB19106 50mg $140
2-Bromo-3',4'-(methylenedioxy)propiophenone FB19106 100mg $255
1-(Benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one 7783CR 100mg $394
2-Bromo-3',4'-(methylenedioxy)propiophenone FB19106 250mg $462.5
1-(BENZO[D][1,3]DIOXOL-5-YL)-2-BROMOPROPAN-1-ONE 95.00% HCH0370762 5MG $505.08
More product size
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2-Bromo-3',4'-(methylenedioxy)propiophenone Properties

Boiling point 345.7±42.0 °C(Predicted)
Density 1.584±0.06 g/cm3(Predicted)
solubility Chloroform: Soluble; DMSO: 1 mg/mL*; Ethanol: 1 mg/mL
form A crystalline solid
InChI InChI=1S/C10H9BrO3/c1-6(11)10(12)7-2-3-8-9(4-7)14-5-13-8/h2-4,6H,5H2,1H3
InChIKey NTPQGLLTGPTOAA-UHFFFAOYSA-N
SMILES C(C1=CC=C2OCOC2=C1)(=O)C(Br)C

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P264-P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338+P310-P363-P405-P501

2-Bromo-3',4'-(methylenedioxy)propiophenone price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth Carbosynth FB19106 2-Bromo-3',4'-(methylenedioxy)propiophenone 52190-28-0 50mg $140 2021-12-16 Buy
Biosynth Carbosynth FB19106 2-Bromo-3',4'-(methylenedioxy)propiophenone 52190-28-0 100mg $255 2021-12-16 Buy
AK Scientific 7783CR 1-(Benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one 52190-28-0 100mg $394 2021-12-16 Buy
Biosynth Carbosynth FB19106 2-Bromo-3',4'-(methylenedioxy)propiophenone 52190-28-0 250mg $462.5 2021-12-16 Buy
American Custom Chemicals Corporation HCH0370762 1-(BENZO[D][1,3]DIOXOL-5-YL)-2-BROMOPROPAN-1-ONE 95.00% 52190-28-0 5MG $505.08 2021-12-16 Buy
Product number Packaging Price Buy
FB19106 50mg $140 Buy
FB19106 100mg $255 Buy
7783CR 100mg $394 Buy
FB19106 250mg $462.5 Buy
HCH0370762 5MG $505.08 Buy

2-Bromo-3',4'-(methylenedioxy)propiophenone Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Solid

Uses

1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one (2-Bromo-3',4'-(methylenedioxy)propiophenone) can be used in the preparation of antifungal agents and MDMA analogs.

Application

2-Bromo-3',4'-(methylenedioxy)propiophenone, also known as 4′-(methylenedioxy)propiophenone, is an analytical reference standard categorized as a precursor in the synthesis of cathinones. This product is intended for research and forensic applications.

Synthesis

Bromine (10.0 mmol) was added to a solution of the ketone (10.0 mmol) in Et2O (25 mL). The solution was stirred for 30 min (until the color of the solution changed from red to light-yellow). Then, the reaction was quenched with water (10 mL), and the mixture was diluted with Et2O (25 mL). The organic layer was washed with a saturated solution of aqueous NaHCO3 (30 mL), a saturated solution of aqueous Na2S2O3 (30 mL), and brine (30 mL), and then it was dried over MgSO4, filtered, and concentrated. The α-bromoketone was purified by flash chromatography on silica gel. 2-Bromo-3',4'-(methylenedioxy)propiophenone [52190-28-0]. This compound was prepared according to the General Procedure from 3,4-methylenedioxypropiophenone (1.78 g, 10.0 mmol). The product was obtained as a white solid (eluted with 50% CH2Cl2 in hexanes; 2.13 g, 82% yield). 1H NMR (CDCl3, 500 MHz) δ 7.64 (d, J= 8.0 Hz, 1H), 7.49 (s, 1H), 6.87 (d, J= 8.0 Hz, 1H), 6.07 (s, 2H), 5.21 (q, J= 7.0 Hz, 1H), 1.88 (d, J= 7.0 Hz, 3H).1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one synthesis

2-Bromo-3',4'-(methylenedioxy)propiophenone synthesis

28281-49-4
52190-28-0
Synthesis of 2-Bromo-3',4'-(methylenedioxy)propiophenone from 3′,4′-(Methylenedioxy)propiophenone

2-Bromo-3',4'-(methylenedioxy)propiophenone Preparation Products And Raw materials

Raw materials

3,4-(METHYLENEDIOXY)BUTYROPHENONE 3′,4′-(Methylenedioxy)propiophenone

Preparation Products

2-Bromo-3',4'-(methylenedioxy)propiophenone Suppliers

Global( 75)Suppliers
Supplier Tel Email Country ProdList Advantage
Xiamen Wonderful Bio Technology Co., Ltd.
+8613043004613 Sara@xmwonderfulbio.com China 283 58
Wuhan Ruichi Technology Co., Ltd
+8613545065237 admin@whrchem.com China 153 58
Shandong Xuhuang New material CoLTD
+86-15095020839 +86-17660422208 China 726 58
Shaanxi Dideu Medichem Co. Ltd 		+8617392709771 1097@dideu.com China 3996 58
Firsky International Trade (Wuhan) Co., Ltd 		+8615387054039 admin@firsky-cn.com China 427 58
Anhui Yiao New Material Technology Co., Ltd 		+86-18033737140 +86-17354101231 sales1@hbganmiao.com China 227 58
Anhui Zhongda Biotechnology Co., Ltd 		+8619956560829 justine@zhongda-biotech.com China 286 58
Anhui Zhongda Biotechnology Co., Ltd 		+8615689548120 linda@zhongda-biotech.com China 193 58
Anhui Ruihan Technology Co., Ltd 		+8617756083858 daisy@anhuiruihan.com China 973 58
Hebei Anlijie Biotechnology Co., Ltd 		+8619031013551 ably@aljbio.com China 144 58
Supplier Advantage
Xiamen Wonderful Bio Technology Co., Ltd.
58
Wuhan Ruichi Technology Co., Ltd
58
Shandong Xuhuang New material CoLTD
58
Shaanxi Dideu Medichem Co. Ltd 		58
Firsky International Trade (Wuhan) Co., Ltd 		58
Anhui Yiao New Material Technology Co., Ltd 		58
Anhui Zhongda Biotechnology Co., Ltd 		58
Anhui Zhongda Biotechnology Co., Ltd 		58
Anhui Ruihan Technology Co., Ltd 		58
Hebei Anlijie Biotechnology Co., Ltd 		58

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View Lastest Price from 2-Bromo-3',4'-(methylenedioxy)propiophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromo-3',4'-(methylenedioxy)propiophenone pictures 2026-01-19 2-Bromo-3',4'-(methylenedioxy)propiophenone
52190-28-0
 US $0.00 / kg 1kg 0.99 10T Shandong Hanjiang Chemical Co., Ltd
2-Bromo-3',4'-(methylenedioxy)propiophenone pictures 2025-12-24 2-Bromo-3',4'-(methylenedioxy)propiophenone
52190-28-0
 US $0.10 / KG 1KG 99.0% 1000Tons Shaanxi Dideu Medichem Co. Ltd
2-Bromo-3',4'-(methylenedioxy)propiophenone pictures 2025-12-08 2-Bromo-3',4'-(methylenedioxy)propiophenone
52190-28-0
 US $0.00-0.00 / kg 1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one 2-Bromo-3',4'-(methylenedioxy)propiophenone 1-(1,3-Benzodioxol-5-yl)-2-broMo-1-propanone 3',4'-Methylenedioxy-α-broMopropiophenone 1-(1,3-benzodioxol-5-yl)-2-bromopropan-1-one 1-Propanone, 1-(1,3-benzodioxol-5-yl)-2-bromo- Bromo-3′ , 4′ - (methylenedioxy) Ascorbyl Pa1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-onelmitate Name 2-Bromo-3',4'-(methylenedioxy)propiophenone pmk 1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one 1-(Benzo [d][1, 3] dioxacyclopentene-5-yl) -2-bromoprop-1-ketone 52190-28-0 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals