CIPROXIFAN
- CAS No.
- 184025-19-2
- Chemical Name:
- CIPROXIFAN
- Synonyms
- CS-109;CIPROXIFAN;FUB359 Maleate;FUB-359 Maleate;FUB 359 Maleate;Ciproxifan Moleate;FUB 359 Maleate salt;Ciproxifan maleate, >=98%;Ciproxifan Maleate (FUB-359);Ciproxifan maleate(FUB-359 maleate)
- CBNumber:
- CB6972679
- Molecular Formula:
- C16H18N2O2.C4H4O4
- Molecular Weight:
- 386.402
- MDL Number:
- MFCD06411563
- MOL File:
- 184025-19-2.mol
- MSDS File:
- SDS
storage temp. | Store at -20°C |
---|---|
solubility | DMSO: soluble32mg/mL |
form | powder |
color | white to beige |
FDA UNII | 5EVQ7IRG99 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H317-H319-H335 | |||||||||
Precautionary statements | P261-P264-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 22-36/37/38-43 | |||||||||
Safety Statements | 26-36/37/39 | |||||||||
WGK Germany | 3 | |||||||||
NFPA 704 |
|
CIPROXIFAN price More Price(23)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C6848 | Ciproxifan maleate ≥98% (HPLC), powder | 184025-19-2 | 5mg | $211 | 2024-03-01 | Buy |
Sigma-Aldrich | C6848 | Ciproxifan maleate ≥98% (HPLC), powder | 184025-19-2 | 25mg | $732 | 2024-03-01 | Buy |
Cayman Chemical | 29513 | Ciproxifan (maleate) | 184025-19-2 | 5mg | $120 | 2024-03-01 | Buy |
Cayman Chemical | 29513 | Ciproxifan (maleate) | 184025-19-2 | 25mg | $435 | 2024-03-01 | Buy |
Cayman Chemical | 29513 | Ciproxifan (maleate) | 184025-19-2 | 1mg | $33 | 2024-03-01 | Buy |
CIPROXIFAN Chemical Properties,Uses,Production
Description
Ciproxifan is a histamine H3 receptor antagonist (Ki = 0.5 nM for inhibition of histamine release in rat synaptosomal preparations). It is selective for histamine H3 over histamine H1 and H2, M3 muscarinic, and α1D- and β1-adrenergic receptors (Kis = 3.15-25 μM), as well as the serotonin (5-HT) receptor subtypes 5-HT1B, 5-HT2A, 5-HT3, and 5-HT4 (Kis = 1.58-15 μM) in radioligand binding assays. Ciproxifan (3-300 nM) inhibits relaxation in precontracted isolated guinea pig ileal longitudinal muscle induced by R-(–)-α-methylhistamine . In vivo, ciproxifan reduces R-(–)-α-methylhistamine-induced water consumption in rats (ED50 = 0.09 mg/kg). It increases wake episode duration and latency to fall asleep in rats when administered at a dose of 2 mg/kg.
Uses
Ciproxifan is a potent histamine H3 receptor antagonist which affects histamine levels in the brain. It may be used in treatments for sleep and neurological disorders.
Biochem/physiol Actions
Potent, selective H3 histamine receptor antagonist.
CIPROXIFAN Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29822 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
View Lastest Price from CIPROXIFAN manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-01-02 | (Z)-but-2-enedioic acid,cyclopropyl-[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone
184025-19-2
|
US $1.00 / KG | 1KG | Min98% HPLC | g/kg/ton | Career Henan Chemical Co |
- (Z)-but-2-enedioic acid,cyclopropyl-[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone
184025-19-2
- US $1.00 / KG
- Min98% HPLC
- Career Henan Chemical Co