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Neosartoricin

CAS No.
1421941-29-8
Chemical Name:
Neosartoricin
Synonyms
Neosartoricin;Neosartoricin A;(2S,3R)-2-(acetyloxy)-3,4-dihydro-3,6,8,9-tetrahydroxy-3-[(3Z)-4-hydroxy-2-oxo-3-penten-1-yl]-10-(3-methyl-2-buten-1-yl)-1(2H)-anthracenone;1(2H)-Anthracenone, 2-(acetyloxy)-3,4-dihydro-3,6,8,9-tetrahydroxy-3-[(3Z)-4-hydroxy-2-oxo-3-penten-1-yl]-10-(3-methyl-2-buten-1-yl)-, (2S,3R)-
CBNumber:
CB69739345
Molecular Formula:
C26H28O9
Molecular Weight:
484.5
MDL Number:
MFCD33021288
MOL File:
1421941-29-8.mol
Last updated:2023-05-21 10:59:17

Neosartoricin Properties

Boiling point 692.7±55.0 °C(Predicted)
Density 1.45±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: soluble; Methanol: soluble
form A solid
pka 4.62±0.60(Predicted)

Neosartoricin Chemical Properties,Uses,Production

Biological Activity

Neosartoricin is a prenylated tricyclic polyketide produced in A. fumigatus and N. fischeri overexpressing the N. fischeri polycyclic prenyltransferase (pcPTase) nsc gene cluster.1 It inhibits the proliferation of anti-CD3 and anti-CD28-stimulated mouse spleen T cells (IC50 = 2.99 μM).

References

1.Chooi, Y.-H., Fang, J., Liu, H., et al.Genome mining of a prenylated and immunosuppressive polyketide from pathogenic fungiOrg. Lett.15(4)780-783(2013)

Neosartoricin Preparation Products And Raw materials

Raw materials

Preparation Products

Neosartoricin Suppliers

Global( 5)Suppliers
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BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
ChemeGen 中国 18818260767 sales@chemegen.com China 6975 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 12007 58
Neosartoricin Neosartoricin A 1(2H)-Anthracenone, 2-(acetyloxy)-3,4-dihydro-3,6,8,9-tetrahydroxy-3-[(3Z)-4-hydroxy-2-oxo-3-penten-1-yl]-10-(3-methyl-2-buten-1-yl)-, (2S,3R)- (2S,3R)-2-(acetyloxy)-3,4-dihydro-3,6,8,9-tetrahydroxy-3-[(3Z)-4-hydroxy-2-oxo-3-penten-1-yl]-10-(3-methyl-2-buten-1-yl)-1(2H)-anthracenone 1421941-29-8