DIHYDROCODEINE TRIFLUOROACETATE
- CAS No.
- 125-28-0
- Chemical Name:
- DIHYDROCODEINE TRIFLUOROACETATE
- Synonyms
- Drocade;Didrate;Drocode;Nadeine;Parzone;Cohydrin;Dihydrin;Novcodin;Dehacodin;Novicodin
- CBNumber:
- CB7100972
- Molecular Formula:
- C20H24F3NO4
- Molecular Weight:
- 399.4
- MDL Number:
- MFCD02253008
- MOL File:
- 125-28-0.mol
| Melting point | 112-113° |
|---|---|
| Boiling point | bp15 248° |
| Density | 1.1412 (rough estimate) |
| refractive index | 1.5740 (estimate) |
| Flash point | 9℃ |
| storage temp. | 2-8°C |
| solubility | DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 10 mg/ml |
| form | A neat solid |
| FDA UNII | N9I9HDB855 |
| EPA Substance Registry System | Morphinan-6-ol, 4,5-epoxy-3-methoxy-17-methyl-, (5?,6?)- (125-28-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H301+H311+H331-H370 | |||||||||
| Precautionary statements | P210-P260-P280-P301+P310-P311 | |||||||||
| Hazard Codes | F,T | |||||||||
| Risk Statements | 11-23/24/25-39/23/24/25 | |||||||||
| Safety Statements | 7-16-36/37-45 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| NFPA 704 |
|
DIHYDROCODEINE TRIFLUOROACETATE Chemical Properties,Uses,Production
Originator
Bicodein,Uquifa
Definition
ChEBI: Dihydrocodeine is a morphinane alkaloid.
Manufacturing Process
The codein was reduced by hydrogen in the presence catalyst Pt (or Pd, or Ni)
and 7,8-dihydrocodein was obtained.
To the 7,8-dihydrocodein tartaric acid was added and mixed, in the result 7,8-
dihydrocodein bitartrate was obtained.
Therapeutic Function
Antitussive, Narcotic analgesic
Safety Profile
Poison by ingestion, intravenous, and subcutaneous routes. Human systemic effects by ingestion and subcutaneous routes: somnolence, miosis (pupillary constriction), and respiratory depression. An analgesic. Can cause drug dependency with repeated doses. When heated to decomposition it emits toxic fumes of NOx. See also CODEINE.
DIHYDROCODEINE TRIFLUOROACETATE Preparation Products And Raw materials
Raw materials
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