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DIHYDROCODEINE TRIFLUOROACETATE

DIHYDROCODEINE TRIFLUOROACETATE structure

CAS No.: 125-28-0

Chemical Name:: DIHYDROCODEINE TRIFLUOROACETATE

Synonyms: Drocade;Didrate;Drocode;Nadeine;Parzone;Cohydrin;Dihydrin;Novcodin;Dehacodin;Novicodin

CBNumber:: CB7100972

Molecular Formula:: C20H24F3NO4

Molecular Weight:: 399.4

MDL Number:: MFCD02253008

MOL File:: 125-28-0.mol

Last updated:2023-06-08 09:02:15

DIHYDROCODEINE TRIFLUOROACETATE Properties

Melting point	112-113°
Boiling point	bp15 248°
Density	1.1412 (rough estimate)
refractive index	1.5740 (estimate)
Flash point	9℃
storage temp.	2-8°C
solubility	DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 10 mg/ml
form	A neat solid
FDA UNII	N9I9HDB855
EPA Substance Registry System	Morphinan-6-ol, 4,5-epoxy-3-methoxy-17-methyl-, (5?,6?)- (125-28-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS06,GHS08

Signal word

Danger

Hazard statements

H225-H301+H311+H331-H370

Precautionary statements

P210-P260-P280-P301+P310-P311

Hazard Codes

F,T

Risk Statements

11-23/24/25-39/23/24/25

Safety Statements

7-16-36/37-45

RIDADR

UN1230 - class 3 - PG 2 - Methanol, solution

NFPA 704

	0
4		0

DIHYDROCODEINE TRIFLUOROACETATE Chemical Properties,Uses,Production

Originator

Bicodein,Uquifa

Definition

ChEBI: Dihydrocodeine is a morphinane alkaloid.

Manufacturing Process

The codein was reduced by hydrogen in the presence catalyst Pt (or Pd, or Ni) and 7,8-dihydrocodein was obtained.
To the 7,8-dihydrocodein tartaric acid was added and mixed, in the result 7,8- dihydrocodein bitartrate was obtained.

Therapeutic Function

Antitussive, Narcotic analgesic

Safety Profile

Poison by ingestion, intravenous, and subcutaneous routes. Human systemic effects by ingestion and subcutaneous routes: somnolence, miosis (pupillary constriction), and respiratory depression. An analgesic. Can cause drug dependency with repeated doses. When heated to decomposition it emits toxic fumes of NOx. See also CODEINE.

DIHYDROCODEINE TRIFLUOROACETATE synthesis

Synthesis of DIHYDROCODEINE TRIFLUOROACETATE from CODEINE

DIHYDROCODEINE TRIFLUOROACETATE Preparation Products And Raw materials

Raw materials

d-Codeine Hydrogen Platinum D-Tartaric acid HYDROCODONE

CODEINE

1of2

Preparation Products

HYDROCODONE BITARTRATE RELATED COMPOUND A CII (70 MG) (MORPHINAN-6-ONE, 4-HYDROXY-3-METHOXY-17-METHYL)

125-28-0(DIHYDROCODEINE TRIFLUOROACETATE)Related Search:

CODEINE DIHYDROCODEINE-6-BETA-D-GLUCURONIDE TRIFLUOROACETATE DIHYDROCODEINE TRIFLUOROACETATE DIHYDROMORPHINE

4,5-alpha-epoxy-3-methoxy-17-methyl-morphinan-6-alpha-o 4,5alpha-Epoxy-3-methoxy-17-methylmorphinan-6alpha-ol 6-alpha-hydrocodol 6α-Hydrocodol Codeine, 7,8-dihydro- (6CI) Morphinan-6-ol, 4,5-epoxy-3-methoxy-17-methyl-, (5α,6α)- Morphinan-6α-ol, 4,5α-epoxy-3-methoxy-17-methyl- (8CI) NSC 231319 α-Hydrocodol Dihydrocodeine (base and/or unspecified salts) Novicodine Dihydrocodeine HCl DIHYDROCODEINE TRIFLUOROACETATE Dihydrocodeine hydrochloride solution Drocade 6alpha-Hydrocodol 6-Hydroxy-3-methoxy-N-methyl-4,5-epoxymorphinan 7,8-dihydro-codein 7,8-Dihydrocodeine 8,14-Dihydroneopine alpha-Hydrocodol Codeine, dihydro- Codhydrine Cohydrin Dehacodin DH-codeine Didrate Dihydrin Dihydrokodein Dihydroneopine Drocode Hydrocodeine Hydrocodin Morphinan-6alpha-ol, 4,5alpha-epoxy-3-methoxy-17-methyl- Morphinan-6-ol, 4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)- Nadeine Novcodin Novicodin Novicondin Paracodin Paracodine Parzone Rapacodin Rapocodin 3-Methoxy-12-methyl-5,6,7,7α,8,9-hexahydro-4aH-8,9c-iminoethanophenanthro[4,5-bcd]furan-5-ol RBOXVHNMENFORY-DNJOTXNNSA-N Dihydrocodeine (CRM) 125-28-0 C18H23NO3C2HF3O