2-Methylthiophenylboronic acid
- CAS No.
- 168618-42-6
- Chemical Name:
- 2-Methylthiophenylboronic acid
- Synonyms
- 3-BORONOTHIOANISOLE;2-BORONOTHIOANISOLE;RARECHEM AH PB 0143;RARECHEM AH PB 0144;2-Methylthiophenylbo;2-Methylthiophenylboronic;2-THIOANISOLEBORONIC ACID;2-thioanisolephenylborate;THIOANISOLE-2-BORONIC ACID;THIOANISOLE-3-BORONIC ACID
- CBNumber:
- CB7116432
- Molecular Formula:
- C7H9BO2S
- Molecular Weight:
- 168.02
- MDL Number:
- MFCD01319105
- MOL File:
- 168618-42-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-(Methylthio)phenylboronic acid | 521248 | 10g | $92.7 |
| 2-(Methylthio)phenylboronic Acid (contains varying amounts of Anhydride) | M1570 | 1g | $46 |
| 2-(Methylthio)phenylboronic Acid (contains varying amounts of Anhydride) | M1570 | 5g | $180 |
| 2-(Methylthio)phenylboronic acid | M218800 | 100mg | $75 |
| 2-(Methylthio)benzeneboronicacid 97% | OR10566 | 100g | $450 |
| More product size | |||
| Melting point | 77-83 °C (lit.) |
|---|---|
| Boiling point | 215C |
| Density | 1,087g/cm |
| refractive index | 1,423-1,425 |
| storage temp. | Inert atmosphere,2-8°C |
| Water Solubility | Slightly soluble in water |
| form | Crystalline Powder |
| pka | 8.50±0.58(Predicted) |
| color | White |
| BRN | 8309529 |
| InChI | InChI=1S/C7H9BO2S/c1-11-7-5-3-2-4-6(7)8(9)10/h2-5,9-10H,1H3 |
| InChIKey | QXBWTYBCNFKURT-UHFFFAOYSA-N |
| SMILES | B(C1=CC=CC=C1SC)(O)O |
| CAS DataBase Reference | 168618-42-6(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36/37/39-36-7/9-37/39-22 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| NFPA 704 |
|
2-Methylthiophenylboronic acid price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 521248 | 2-(Methylthio)phenylboronic acid | 168618-42-6 | 10g | $92.7 | 2025-07-31 | Buy |
| TCI Chemical | M1570 | 2-(Methylthio)phenylboronic Acid (contains varying amounts of Anhydride) | 168618-42-6 | 1g | $46 | 2025-07-31 | Buy |
| TCI Chemical | M1570 | 2-(Methylthio)phenylboronic Acid (contains varying amounts of Anhydride) | 168618-42-6 | 5g | $180 | 2025-07-31 | Buy |
| TRC | M218800 | 2-(Methylthio)phenylboronic acid | 168618-42-6 | 100mg | $75 | 2021-12-16 | Buy |
| Apolloscientific | OR10566 | 2-(Methylthio)benzeneboronicacid 97% | 168618-42-6 | 100g | $450 | 2021-12-16 | Buy |
2-Methylthiophenylboronic acid Chemical Properties,Uses,Production
Chemical Properties
White crystalline powde
Uses
Reactant for:
- Palladium-catalyzed cross-coupling reactions
- Suzuki-Miyaura coupling reactions
Uses
suzuki reaction
Synthesis
5419-55-6
19614-16-5
168618-42-6
Part A: Preparation of 2-methylthiophenylboronic acid. 2-Bromothioanisole (29.0 g, 143 mmol) was dissolved in anhydrous tetrahydrofuran (400 mL) and the solution was cooled to -75°C. n-Butyllithium (62.0 mL, 2.5 M hexane solution, 155 mmol) was added slowly over 50 minutes. After stirring for 25 min, triisopropyl borate (46 mL, 199 mmol) was added dropwise over 35 min. The cold bath was removed and the reaction mixture was stirred at room temperature for 16 hours. The resulting solution was cooled in an ice bath and 6 M hydrochloric acid (100 mL) was added. The mixture was stirred at room temperature for 5 hours and then concentrated to half the original volume. The concentrate was partitioned between ether and water. The organic layer was extracted with 2 M sodium hydroxide solution, subsequently acidified with 6 M hydrochloric acid, concentrated again, and extracted several times with ether. The ether extracts were combined, dried with sodium sulfate, filtered and the solvent evaporated to give a beige solid product (20.4 g, 85% yield).1H-NMR (CDCl3) δ: 8.01 (dd, 1H, J = 7.3, J' = 1.4), 7.53 (dd, 1H, J = 7.7, J' = 1.1), 7.43 (td, 1H, J = 7.3, J' = 1.8), 7.34 (td, 1H, J = 7.3, J'= 1.5), 6.22 (s, 2H), 2.50 (s, 3H).
References
[1] Patent: EP946508, 2009, B1. Location in patent: Page/Page column 60
[2] Patent: EP1491187, 2004, A1. Location in patent: Page 26
2-Methylthiophenylboronic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1085 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13505 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| BAYNOE CHEM CO.,LTD | +86-21-34783353 +8615000719740 | baynoe@baynoe.com | CHINA | 934 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
View Lastest Price from 2-Methylthiophenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 2-Methylthiophenylboronic acid
168618-42-6
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2023-12-05 | 2-Methylthiophenylboronic acid
168618-42-6
|
US $0.00-0.00 / kg | 1kg | 99.9% | 30000 Kg | Hebei Xinsheng New Material Technology Co., LTD. | |
 |
2023-11-15 | 2-Methylthiophenylboronic acid
168618-42-6
|
US $0.00-0.00 / kg | 1kg | 99.9% | 30000 Kg | Hebei Xinsheng New Material Technology Co., LTD. |
-
- 2-Methylthiophenylboronic acid
168618-42-6
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2-Methylthiophenylboronic acid
168618-42-6
- US $0.00-0.00 / kg
- 99.9%
- Hebei Xinsheng New Material Technology Co., LTD.
-
- 2-Methylthiophenylboronic acid
168618-42-6
- US $0.00-0.00 / kg
- 99.9%
- Hebei Xinsheng New Material Technology Co., LTD.
