ChemicalBook >> CAS DataBase List >>4-FLUORO-3-METHOXYBENZALDEHYDE

4-FLUORO-3-METHOXYBENZALDEHYDE

4-FLUORO-3-METHOXYBENZALDEHYDE structure

CAS No.: 128495-46-5

Chemical Name:: 4-FLUORO-3-METHOXYBENZALDEHYDE

Synonyms: uoro-m-anisaL;4-FLUORO-M-ANISALDEHYDE;4-Fluoro-m-anisaldehyde>3-METHOXY-4-FLUOROBENZALDEHYDE;4-FLUORO-3-METHOXYBENZALDEHYDE;4-Fluoro-3-methoxybenzaldehyde97%;Benzaldehyde, 4-fluoro-3-methoxy-;4-Fluoro-3-methoxybenzaldehyde 97%;4-Fluoro-M-anisaldehyde, 96.0%(GC);4-Fluoro-3-methoxybenzaldehyde ,98%

CBNumber:: CB7119640

Molecular Formula:: C8H7FO2

Molecular Weight:: 154.14

MDL Number:: MFCD00143320

MOL File:: 128495-46-5.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:44

Request For Quotation

4-FLUORO-3-METHOXYBENZALDEHYDE Properties

Melting point	58-62 °C(lit.)
Boiling point	93 °C(Press: 4.5 Torr)
Density	1.192±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to crystal
color	White to Light yellow
Sensitive	Air Sensitive
BRN	5178063
InChI	InChI=1S/C8H7FO2/c1-11-8-4-6(5-10)2-3-7(8)9/h2-5H,1H3
InChIKey	NALVGTOMKSKFFV-UHFFFAOYSA-N
SMILES	C(=O)C1=CC=C(F)C(OC)=C1
CAS DataBase Reference	128495-46-5(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H302-H315-H318-H335

Precautionary statements

P280-P301+P312+P330-P302+P352-P305+P351+P338+P310

Hazard Codes

Xn,Xi

Risk Statements

22-37/38-41-36/37/38

Safety Statements

26-36

WGK Germany

HazardClass

IRRITANT

HS Code

29124990

NFPA 704

	1
2		0

4-FLUORO-3-METHOXYBENZALDEHYDE price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	652687	4-Fluoro-3-methoxybenzaldehyde 97%	128495-46-5	5g	$38.57	2025-07-31	Buy
Sigma-Aldrich	652687	4-Fluoro-3-methoxybenzaldehyde 97%	128495-46-5	25g	$237	2023-06-20	Buy
TCI Chemical	F0401	4-Fluoro-m-anisaldehyde >96.0%(GC)	128495-46-5	1g	$27	2025-07-31	Buy
TCI Chemical	F0401	4-Fluoro-m-anisaldehyde >96.0%(GC)	128495-46-5	5g	$82	2025-07-31	Buy
TCI Chemical	F0401	4-Fluoro-m-anisaldehyde >96.0%(GC)	128495-46-5	25g	$247	2025-07-31	Buy

Product number	Packaging	Price	Buy
652687	5g	$38.57	Buy
652687	25g	$237	Buy
F0401	1g	$27	Buy
F0401	5g	$82	Buy
F0401	25g	$247	Buy

4-FLUORO-3-METHOXYBENZALDEHYDE Chemical Properties,Uses,Production

Chemical Properties

White to yellow to tan powder or crystal or crystalline powder

Uses

Synthesis Reference(s)

Journal of Medicinal Chemistry, 33, p. 2408, 1990 DOI: 10.1021/jm00171a014

Synthesis

128495-45-4

128495-46-5

General procedure for the synthesis of 3-methoxy-4-fluorobenzaldehyde from 3-methoxy-4-fluorobenzyl alcohol: (4-fluoro-3-methoxyphenyl)methanol (5.00 g, 0.03 mol) was mixed with manganese dioxide (33.4 g, 0.38 mol) in dichloromethane (100 mL) under nitrogen protection, and the reaction was stirred for 16 hr under mild reflux conditions. Upon completion of the reaction, the reaction mixture was cooled to room temperature, filtered through Arbacel, and the filtrate was concentrated in vacuum to afford 3-methoxy-4-fluorobenzaldehyde (4.18 g, 0.027 mol, 85% yield) as a white solid. The product was characterized by 1H NMR (CDCl3, 400 MHz): δ 3.96 (s, 3H), 7.23 (d, 1H), 7.43 (m, 1H), 7.50 (d, 1H), 9.91 (s, 1H). The melting point is 61-63°C. Elemental analysis results: measured value C, 62.18; H, 4.54%. Theoretical value (C8H7FO2): C, 62.34; H, 4.58%.

References

[1] Journal of Medicinal Chemistry, 1990, vol. 33, # 9, p. 2408 - 2412
[2] Patent: WO2004/52372, 2004, A1. Location in patent: Page 72
[3] Patent: WO2008/87512, 2008, A1. Location in patent: Page/Page column 43
[4] Patent: EP2862571, 2015, A1. Location in patent: Paragraph 0164; 0165
[5] Patent: US2015/166559, 2015, A1. Location in patent: Paragraph 0220; 0221

4-FLUORO-3-METHOXYBENZALDEHYDE synthesis

Synthesis of 4-FLUORO-3-METHOXYBENZALDEHYDE from 4-FLUORO-3-METHOXYBENZYL ALCOHOL

4-FLUORO-3-METHOXYBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Acetone Diethyl ether Ethyl acetate Dichloromethane Potassium permanganate

2-FLUORO-5-METHYLPHENOL PETROLEUM ETHER Sulfuric acid Dimethyl sulfate 4-FLUORO-3-METHOXYBENZYL ALCOHOL

1of2

Preparation Products

Ethyl 2-(6-fluoro-5-hydroxy-2,3-dihydro-1H-inden-1-yl)acetate 1,7-DIFLUORO-6-METHOXYISOQUINOLINE 1-(4-FLUORO-3-METHOXYPHENYL)ETHAN-1-OL Ethyl 2-(6-fluoro-5-methoxy-2,3-dihydro-1H-inden-1-ylidene)acetate Benzenemethanamine, 4-fluoro-3-methoxy- (9CI)

4-FLUORO-3-METHOXYBENZALDEHYDE Suppliers

Global( 275)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8617732866630	abby@chuanghaibio.com	China	8773	58
Hebei Mujin Biotechnology Co.,Ltd	+86-13288715578	sales@hbmojin.com	China	12647	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2472	58
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29731	60
Fluoropharm Co., Ltd.	+86-0571-85586753 +86-13336034509	sales@fluoropharm.com	China	1445	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88299272	info@edengenechem.com	China	2176	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Capot Chemical Co.,Ltd.	60
Fluoropharm Co., Ltd.	60
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Changzhou Ditong Chemical Co.,Ltd	58
Hubei xin bonus chemical co. LTD	58

View Lastest Price from 4-FLUORO-3-METHOXYBENZALDEHYDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-07-07	4-FLUORO-3-METHOXYBENZALDEHYDE 128495-46-5	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mujin Biotechnology Co.,Ltd
2025-06-24	4-FLUORO-3-METHOXYBENZALDEHYDE 128495-46-5	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2024-04-23	4-Fluoro-m-anisaldehyde 128495-46-5	US $100.00-30.00 / kg	1kg	99.93%	1000kg per week	Ouhuang Engineering Materials (Hubei) Co., Ltd

4-FLUORO-3-METHOXYBENZALDEHYDE
128495-46-5
US $0.00 / KG
99%
Hebei Mujin Biotechnology Co.,Ltd

4-FLUORO-3-METHOXYBENZALDEHYDE
128495-46-5
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

4-Fluoro-m-anisaldehyde
128495-46-5
US $100.00-30.00 / kg
99.93%
Ouhuang Engineering Materials (Hubei) Co., Ltd

4-FLUORO-3-METHOXYBENZALDEHYDE Spectrum

4-FLUORO-3-METHOXYBENZALDEHYDE(128495-46-5)MS 4-FLUORO-3-METHOXYBENZALDEHYDE(128495-46-5)¹HNMR 4-FLUORO-3-METHOXYBENZALDEHYDE(128495-46-5)¹³CNMR 4-FLUORO-3-METHOXYBENZALDEHYDE(128495-46-5)IR1 4-FLUORO-3-METHOXYBENZALDEHYDE(128495-46-5)IR2

128495-46-5(4-FLUORO-3-METHOXYBENZALDEHYDE)Related Search:

4-FLUORO-3-METHOXYBENZALDEHYDE 4-FLUORO-3-METHOXYBENZOIC ACID 4-FLUORO-3-METHOXYACETOPHENONE 3-Methoxy-2,4,5-trifluorobenzoic acid 3-METHOXY-2,4,5-TRIFLUOROBENZAMIDE

Levofloxacin carboxylic acid 2,4-DIFLUORO-3-METHOXYBENZALDEHYDE 2,4,5-Trifluoro-3-methoxybenzoyl chloride 4-Fluoro-3-phenoxybenzaldehyde 2,4-Difluoro-3-methoxybenzoic acid

2,4-DIFLUORO-3-METHOXY ACETOPHENONE 6-CHLORO-2-FLUORO-3-METHOXYBENZALDEHYDE 3-CHLORO-5-FLUORO-4-METHOXYBENZALDEHYDE 2-FLUORO-4-METHOXYBENZALDEHYDE,2-Fluoro-4-methoxybenzaldehyde 97%,2-Fluoro-4-methoxybenzaldehyde97% 3-Fluoro-5-methoxybenzaldehyde 97%,3-Fluoro-5-methoxybenzaldehyde97%

3-FLUORO-4-METHOXYBENZALDEHYDE,3-Fluoro-4-Methoxybenzaldehyde/3-Fluoro-P-Anisaldehyde/M-Fluoro-P-Anisaldehyde/ 2-FLUORO-5-METHOXYBENZALDEHYDE,2-Fluoro-5-methoxybenzaldehyde 98%,2-Fluoro-5-methoxybenzaldehyde98% 4-FLUORO-2-METHOXYBENZALDEHYDE

1of4

4-Fluoro-3-methoxybenzaldehyde 97% 4-Fluoro-3-methoxybenzaldehyde97% 4-FLUORO-M-ANISALDEHYDE 4-FLUORO-3-METHOXYBENZALDEHYDE 3-METHOXY-4-FLUOROBENZALDEHYDE 4-Fluoro-3-methoxybenzaldehyde ,98% 2-Fluoro-5-formylanisole, 4-Fluoro-m-anisaldehyde 4-Fluoro-M-anisaldehyde, 96.0%(GC) 4-Fluoro-3-methoxybenzaldehyde≥ 98.5% (HPLC) 4-Fluoro-m-anisaldehyde> uoro-m-anisaL Benzaldehyde, 4-fluoro-3-methoxy- 4-FLUORO-3-METHOXYBENZALDEHYDE ISO 9001：2015 REACH 3'-Nitro-2,2,3-trifluoroacetophenone 128495-46-5 Organic Building Blocks C8 Carbonyl Compounds Building Blocks Aldehydes Fluorine series C8 Carbonyl Compounds Aryl Fluorinated Building Blocks Building Blocks C7-C8 Carbonyl Compounds Chemical Synthesis Fluorinated Building Blocks Organic Building Blocks Organic Fluorinated Building Blocks Other Fluorinated Organic Building Blocks Aromatic Aldehydes & Derivatives (substituted) Benzaldehyde Adehydes, Acetals & Ketones Anisoles, Alkyloxy Compounds & Phenylacetates Fluorine Compounds Aldehydes