2-Cyano-5-nitropyridine
- CAS No.
- 100367-55-3
- Chemical Name:
- 2-Cyano-5-nitropyridine
- Synonyms
- 5-Nitropicolinonitrile;6-CYANO-3-NITROPYRIDINE;2-CYANO-5-NITROPYRIDINE;2-Cyano-5-nitropyridine 95+%;5-Nitropyridin-2-carbonitrile;5-Nitro-2-pyridinecarbonitrile;5-nitropyridine-2-carbonitrile;2-PYRIDINECARBONITRILE, 5-NITRO-;3-bromo-6-methyl-1H-pyridin-2-one;2-Pyridinecarbonitrile,5-nitro-(9CI)
- CBNumber:
- CB7122336
- Molecular Formula:
- C6H3N3O2
- Molecular Weight:
- 149.11
- MDL Number:
- MFCD07368184
- MOL File:
- 100367-55-3.mol
| Product description | Number | Pack Size | Price |
| 2-Cyano-5-nitropyridine | C8395-86 | 100mg | $403 |
| 2-Cyano-5-nitropyridine | C982025 | 1g | $970 |
| 5-NITROPYRIDINE-2-CARBONITRILE 95.00% | CHM0012842 | 1G | $1593.9 |
| 5-NITROPYRIDINE-2-CARBONITRILE 95.00% | CHM0012842 | 100MG | $704.55 |
| 2-Cyano-5-nitropyridine | 4H55-1-73 | 25g | $750 |
| More product size | |||
| Melting point | 43 °C |
|---|---|
| Boiling point | 344.6±27.0 °C(Predicted) |
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Ethyl Acetate, Methanol |
| form | Solid |
| pka | -4.35±0.10(Predicted) |
| color | Green |
| CAS DataBase Reference | 100367-55-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H302+H312+H332-H315 |
| Precautionary statements | P280-P302+P352-P305+P351+P338 |
| HS Code | 2933399990 |
2-Cyano-5-nitropyridine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | C8395-86 | 2-Cyano-5-nitropyridine | 100367-55-3 | 100mg | $403 | 2021-12-16 | Buy |
| TRC | C982025 | 2-Cyano-5-nitropyridine | 100367-55-3 | 1g | $970 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0012842 | 5-NITROPYRIDINE-2-CARBONITRILE 95.00% | 100367-55-3 | 1G | $1593.9 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0012842 | 5-NITROPYRIDINE-2-CARBONITRILE 95.00% | 100367-55-3 | 100MG | $704.55 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H55-1-73 | 2-Cyano-5-nitropyridine | 100367-55-3 | 25g | $750 | 2021-12-16 | Buy |
2-Cyano-5-nitropyridine Chemical Properties,Uses,Production
Chemical Properties
Green Solid
Uses
2-Cyano-5-nitropyridine can be used as a useful synthetic intermediate.
Synthesis
4487-59-6
143-33-9
544-92-3
100367-55-3
Synthesis of Compound E: Copper(I) cyanide (662 mg, 7.34 mmol) and sodium cyanide (242 mg, 4.93 mmol) were dissolved in N,N-dimethylformamide (7.5 mL) and stirred at 150 °C for 25 min. Subsequently, a solution of 2-bromo-5-nitropyridine (113 mg, 0.700 mmol) dissolved in N,N-dimethylformamide (2.5 mL) (pre-dissolved completely at 100 °C) was added to the above mixture and the reaction was continued to be stirred at 150 °C for 100 min. The progress of the reaction was monitored by TLC (unfolding agent: ethyl acetate/hexane = 1:3). Upon completion of the reaction, the reaction was quenched by the addition of 10 mL of aqueous 1M potassium dihydrogen phosphate and extracted with ethyl acetate (50 mL x 3). The organic phases were combined and washed sequentially with water (100 mL) and saturated saline (100 mL). The organic layer was dried over anhydrous magnesium sulfate and filtered, and concentrated under reduced pressure to remove the solvent. The product was purified by fast column chromatography (eluent: ethyl acetate/hexane = 1:7→1:3) to afford 2-cyano-5-nitropyridine E (624 mg, 4.19 mmol) as a yellow oil in 85% yield.1H NMR (300 MHz, CDCl3) δ: 9.54 (dd, 1H, J = 2.5, 0.7 Hz, Py-H), 8.68 (dd, 1H, J = 8.4, 2.5 Hz, Py-H), 7.98 (dd, 1H, J = 8.4, 0.7 Hz, Py-H).
References
[1] Journal of Medicinal Chemistry, 2008, vol. 51, # 8, p. 2400 - 2411
[2] Patent: EP2070908, 2009, A1. Location in patent: Page/Page column 11-12
2-Cyano-5-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29847 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10405 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10237 | 58 |
| HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3461 | 58 |
View Lastest Price from 2-Cyano-5-nitropyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 2-Cyano-5-nitropyridine
100367-55-3
|
US $1.00 / kg | 1kg | 98% | 200kg | Career Henan Chemical Co |
-
- 2-Cyano-5-nitropyridine
100367-55-3
- US $1.00 / kg
- 98%
- Career Henan Chemical Co
100367-55-3(2-Cyano-5-nitropyridine)Related Search:
1of4
