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4-Iodopyridine

CAS No.
15854-87-2
Chemical Name:
4-Iodopyridine
Synonyms
4-Iodopyride;4-lodopyridine;p-iodopyridine;4-IODOPYRIDINE;BUTTPARK 96\50-18;4-pyridine iodide;4-Iodopyridine>Pyridine, 4-iodo-;4-Iodopyridine 96%;4-Iodine Pyridine
CBNumber:
CB7124406
Molecular Formula:
C5H4IN
Molecular Weight:
205
MDL Number:
MFCD02093937
MOL File:
15854-87-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:22
Product description Number Pack Size Price
4-Iodopyridine 96% 722170 1g $114
4-Iodopyridine >98.0%(GC)(T) I0673 5g $154
4-Iodopyridine >98.0%(GC)(T) I0673 25g $457
4-Iodopyridine I719430 25g $250
4-IODOPYRIDINE 45661 1g $75.14
More product size

4-Iodopyridine Properties

Melting point 94-99 °C
Boiling point 212~215℃
Density 1.081g/cm3
refractive index 1.5290
storage temp. -20°C
solubility soluble in Methanol
form Crystals or Powder
pka pK1:4.02(+1) (20°C)
color Pale brown to dark green-brown
Sensitive Light Sensitive
BRN 1594
InChI InChI=1S/C5H4IN/c6-5-1-3-7-4-2-5/h1-4H
InChIKey RTLUPHDWSUGAOS-UHFFFAOYSA-N
SMILES C1=NC=CC(I)=C1
CAS DataBase Reference 15854-87-2(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
target organs Respiratory system
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-41-37/38-22
Safety Statements  26-36-39
WGK Germany  3
Hazard Note  Irritant/Light Sensitive
HS Code  29333990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

4-Iodopyridine price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 722170 4-Iodopyridine 96% 15854-87-2 1g $114 2026-04-30 Buy
TCI Chemical I0673 4-Iodopyridine >98.0%(GC)(T) 15854-87-2 5g $154 2026-04-30 Buy
TCI Chemical I0673 4-Iodopyridine >98.0%(GC)(T) 15854-87-2 25g $457 2026-04-30 Buy
TRC I719430 4-Iodopyridine 15854-87-2 25g $250 2021-12-16 Buy
GFS CHEMICALS 45661 4-IODOPYRIDINE 15854-87-2 1g $75.14 2021-12-16 Buy
Product number Packaging Price Buy
722170 1g $114 Buy
I0673 5g $154 Buy
I0673 25g $457 Buy
I719430 25g $250 Buy
45661 1g $75.14 Buy

4-Iodopyridine Chemical Properties,Uses,Production

Chemical Properties

White to off-white crystals,turns brown on storage

Uses

4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.

Synthesis

Pyridine

110-86-1

4-Iodopyridine

15854-87-2

GENERAL METHODS: [Li(TMP)Zn(tBu)2] 1 was prepared according to literature methods in a 0.4 mmol scale solution of THF. Pyridine (0.032 mL, 0.4 mmol) was added to this solution at 0°C and the resulting light orange colored reaction mixture was allowed to stir for 2 h at room temperature. Subsequently, the reaction was quenched with I2 (508 mg, dissolved in 1 mL THF) and stirring was continued for 1 hour. A 10% Na2S2O3 solution was added until the color of the reaction mixture faded, and then the product was extracted with DCM (3 x 1 mL). The organic extracts were combined, dried with MgSO4 and concentrated under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography using EtOAc:heptane (20:80→30:70) as eluent to afford 4-iodopyridine (compound 5a) as an off-white solid (42 mg, 50% yield).1H NMR (400 MHz, CDCl3) δ ppm 7.59-7.86 (m, 2H), 8.07-8.44 (m 2H).

References

[1] Tetrahedron Letters, 2011, vol. 52, # 36, p. 4590 - 4594
[2] Journal of Organic Chemistry, 1984, vol. 49, # 20, p. 3857 - 3859

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View Lastest Price from 4-Iodopyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Iodopyridine pictures 2025-11-18 4-Iodopyridine
15854-87-2
US $1.10 / g 1g 99.00% 100 Tons min Dideu Industries Group Limited
4-Iodopyridine pictures 2025-04-04 4-Iodopyridine
15854-87-2
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
4-iodopyridine pictures 2023-04-21 4-iodopyridine
15854-87-2
US $0.00 / KG 1KG 98% 1000 Wuhan Silworld Chemical Co.,Ltd
  • 4-Iodopyridine pictures
  • 4-Iodopyridine
    15854-87-2
  • US $1.10 / g
  • 99.00%
  • Dideu Industries Group Limited
  • 4-Iodopyridine pictures
  • 4-Iodopyridine
    15854-87-2
  • US $0.00-0.00 / kg
  • 98%
  • Henan Aochuang Chemical Co.,Ltd.
  • 4-iodopyridine pictures
  • 4-iodopyridine
    15854-87-2
  • US $0.00 / KG
  • 98%
  • Wuhan Silworld Chemical Co.,Ltd
BUTTPARK 96\50-18 4-IODOPYRIDINE p-iodopyridine SPECS AC-907/25004389 TIMTEC-BB SBB009104 4-Iodopyride 4-Iodopyridine 96% 4-lodopyridine 4-Iodopyridine, GC 96% 4-Iodopyridine,96% 4-Iodine Pyridine 4-Iodopyridine, 96% 1GR 4-Iodopyridine ,98% 4-Iodopyridine,p-Iodopyridine 4-pyridine iodide 4-IODOPYRIDINE, 98%4-IODOPYRIDINE, 98%4-IODOPYRIDINE, 98%4-IODOPYRIDINE, 98% 4-Iodopyridine> Pyridine, 4-iodo- 4-Iodopyridine ISO 9001:2015 REACH 15854-87-2 C5H4IN Pharmaceutical intermediates Halopyridines Iodopyridines Halogenated Organohalides Pyridines, Pyrimidines, Purines and Pteredines pharmacetical Halides Pyridine Pyridines derivates blocks Iodides Pyridines