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Columbin

CAS No.
546-97-4
Chemical Name:
Columbin
Synonyms
Tinosporin;Columbin USP/EP/BP;Columbin >=95% (LC/MS-ELSD);Columbin, 98%, from limacia sagittata;(1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione;(1s,2s,3s,5s,8r,11r,12s)-5-(3-furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione;(1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione;diterpenoid,Cyclooxygenase,anti-inflammatory,COX-1,Inhibitor,Trypanosoma brucei,Columbin,furanolactone,COX,anti-trypanosomal,Parasite,inhibit;(1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione;(1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione
CBNumber:
CB71246910
Molecular Formula:
C20H22O6
Molecular Weight:
358.39
MDL Number:
MFCD02682955
MOL File:
546-97-4.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:05

Columbin Properties

Melting point 190-191℃
alpha D +52.5° (pyridine)
Boiling point 410.82°C (rough estimate)
Density 1.36
refractive index 1.4450 (estimate)
storage temp. -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.03 mg/ml
form Cryst.
pka 12.14±0.70(Predicted)
FDA UNII KKI91P85GE

SAFETY

Risk and Safety Statements

WGK Germany  3
HS Code  29322090

Columbin price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SMB00086 Columbin ≥95% (LC/MS-ELSD) 546-97-4 1mg $303 2024-03-01 Buy
Cayman Chemical 24105 Columbin ≥98% 546-97-4 1mg $44 2024-03-01 Buy
Cayman Chemical 24105 Columbin ≥98% 546-97-4 5mg $140 2024-03-01 Buy
Cayman Chemical 24105 Columbin ≥98% 546-97-4 10mg $235 2024-03-01 Buy
Cayman Chemical 24105 Columbin ≥98% 546-97-4 25mg $533 2024-03-01 Buy
Product number Packaging Price Buy
SMB00086 1mg $303 Buy
24105 1mg $44 Buy
24105 5mg $140 Buy
24105 10mg $235 Buy
24105 25mg $533 Buy

Columbin Chemical Properties,Uses,Production

Uses

Columbin is a furanolactone diterpene isolated from the roots of Jateorhiza and Tinospora species and is used in Asian and African folk medicine for analgesic and antipyretic properties.

Definition

ChEBI: Columbin is an organic heterotricyclic compound and an organooxygen compound.

Columbin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 115)Suppliers
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Shanghai Zheyan Biotech Co., Ltd.
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Chengdu Biopurify Phytochemicals Ltd.
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Shaanxi Pioneer Biotech Co., Ltd .
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+86-519-519-85557386 marketing1@neostarunited.com China 8349 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58

View Lastest Price from Columbin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Columbin pictures 2023-02-24 Columbin
546-97-4
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
(1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.0<sup>2,11</sup>.0<sup>3,8</sup>]hexadec-15-ene-7,13-dione pictures 2020-01-10 (1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione
546-97-4
US $9.80 / KG 1KG ≥98% 20 tons Career Henan Chemical Co
  • Columbin pictures
  • Columbin
    546-97-4
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
(1s,2s,3s,5s,8r,11r,12s)-5-(3-furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione (1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione (1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione Tinosporin Columbin, 98%, from limacia sagittata (1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione (1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione 1,4-Etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione, 9-(3-furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-, (1R,4R,4aR,6aR,9S,10aS,10bS)- Columbin >=95% (LC/MS-ELSD) Columbin USP/EP/BP (2S,4AR,6aR,7R,10R,10aS,10bS)-2-(furan-3-yl)-7-hydroxy-6a,10b-dimethyl-4a,5,6,6a,7,10,10a,10b-octahydro-1H-10,7-(epoxymethano)benzo[f]isochromene-4,12(2H)-dione diterpenoid,Cyclooxygenase,anti-inflammatory,COX-1,Inhibitor,Trypanosoma brucei,Columbin,furanolactone,COX,anti-trypanosomal,Parasite,inhibit 546-97-4 Miscellaneous Natural Products