(R)-Pyrrolidin-3-ylmethanol
- CAS No.
- 110013-18-8
- Chemical Name:
- (R)-Pyrrolidin-3-ylmethanol
- Synonyms
- D-β-Prolinol;D-beta-Prolinol;CAS:110013-18-8;D-^b-Prolinol, 95%;(R)-3-(HydroxymethyL;(R)-BETA-PROLINOL HCL;(R)-3-Pyrrolidin-Methanol;(R)-3-Pyrrolidinemethanol;(3R)-3-Pyrrolidinemethanol;(r)-pyrrolidin-3-ylmethanol
- CBNumber:
- CB71267605
- Molecular Formula:
- C5H11NO
- Molecular Weight:
- 101.15
- MDL Number:
- MFCD09607969
- MOL File:
- 110013-18-8.mol
| Product description | Number | Pack Size | Price |
| (3R)-3-pyrrolidinylmethanol | P999050 | 1g | $275 |
| [R]-3-Pyrrolidinemethanol | OR309158 | 1g | $284 |
| (R)-3-Hydroxymethylpyrrolidine | 4H56-1-R0 | 1g | $349 |
| (R)-3-(Hydroxymethyl)pyrrolidine 95+% ee | AS22856 | 5G | $385 |
| (R)-3-Hydroxymethylpyrrolidine | 4H56-1-R0 | 250mg | $115 |
| More product size | |||
| Boiling point | 176 °C |
|---|---|
| Density | 0.978 |
| Flash point | 90 °C |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 14.93±0.10(Predicted) |
| form | powder |
| color | Yellow |
| Water Solubility | Slightly soluble in water. |
| Sensitive | Hygroscopic |
| InChI | InChI=1S/C5H11NO/c7-4-5-1-2-6-3-5/h5-7H,1-4H2/t5-/m1/s1 |
| InChIKey | QOTUIIJRVXKSJU-RXMQYKEDSA-N |
| SMILES | N1CC[C@@H](CO)C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | F,C | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37-60 | |||||||||
| TSCA | No | |||||||||
| HS Code | 2933998090 | |||||||||
| NFPA 704 |
|
(R)-Pyrrolidin-3-ylmethanol price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | P999050 | (3R)-3-pyrrolidinylmethanol | 110013-18-8 | 1g | $275 | 2021-12-16 | Buy |
| Apolloscientific | OR309158 | [R]-3-Pyrrolidinemethanol | 110013-18-8 | 1g | $284 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H56-1-R0 | (R)-3-Hydroxymethylpyrrolidine | 110013-18-8 | 1g | $349 | 2021-12-16 | Buy |
| Activate Scientific | AS22856 | (R)-3-(Hydroxymethyl)pyrrolidine 95+% ee | 110013-18-8 | 5G | $385 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H56-1-R0 | (R)-3-Hydroxymethylpyrrolidine | 110013-18-8 | 250mg | $115 | 2021-12-16 | Buy |
(R)-Pyrrolidin-3-ylmethanol Chemical Properties,Uses,Production
Uses
It is an intermediate in organic syntheses.
Synthesis
35309-35-4
85310-69-6
The general procedure for the synthesis of 3-pyrrolidinemethanol from methyl 5-oxopyrrolidine-3-carboxylate is as follows: 2 kg of methyl 5-oxo-3-pyrrolidinecarboxylate is dissolved in 20 liters of tetrahydrofuran, and 1.9 kg of sodium borohydride is added in batches at room temperature. Subsequently, 3.9 kg of boron trifluoride ether solution was slowly added. After the dropwise addition was completed, the reaction mixture was stirred at room temperature for 10 minutes and then heated to reflux the reaction for about 4 hours. Upon completion of the reaction, the reaction was quenched by addition of water, extracted with ethyl acetate and concentrated to give a light yellow oily liquid. The oily liquid was dissolved in ethanol, cooled to 20°C and then 500 g of sodium borohydride was added and the reaction was refluxed for 2 hours. The reaction was again quenched with water, extracted with ethyl acetate, and the organic phase was washed with saturated aqueous sodium bicarbonate and saturated brine in turn, and finally the organic phase was concentrated to obtain 1.2 kg of 3-pyrrolidinylmethanol with a yield of 86%.
References
[1] Patent: CN106588738, 2017, A. Location in patent: Paragraph 0032; 0034; 0039; 0042; 0044
(R)-Pyrrolidin-3-ylmethanol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13595 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29798 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
View Lastest Price from (R)-Pyrrolidin-3-ylmethanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-04-04 | (R)-Pyrrolidin-3-ylmethanol
110013-18-8
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
|
|
 |
2019-12-23 | (R)-Pyrrolidin-3-ylmethanol
110013-18-8
|
US $1.00 / g | 1g | 99% | 1000KGS | Career Henan Chemical Co |
-
- (R)-Pyrrolidin-3-ylmethanol
110013-18-8
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- (R)-Pyrrolidin-3-ylmethanol
110013-18-8
- US $1.00 / g
- 99%
- Career Henan Chemical Co
