ChemicalBook >> CAS DataBase List >>alpha-Methyldopa sesquihydrate
alpha-Methyldopa sesquihydrate
- CAS No.
- 41372-08-1
- Chemical Name:
- alpha-Methyldopa sesquihydrate
- Synonyms
- (S)-2-AMINO-3-(3,4-DIHYDROXYPHENYL)-2-METHYLPROPIONIC ACID SESQUIHYDRATE;C07194;hyperpax;IDI1_000142;Prestwick2_;KBio2_001417;KBio2_003985;KBio2_006553;KBio3_001521;SPBio_001056
- CBNumber:
- CB7135325
- Molecular Formula:
- C10H15NO5
- Molecular Weight:
- 229.23
- MDL Number:
- MFCD30179484
- MOL File:
- 41372-08-1.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:13
| Melting point | >300 °C(lit.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | Slightly soluble in water, very slightly soluble in ethanol (96 per cent). It is freely soluble in dilute mineral acids. |
| color | White to Off-White |
| optical activity | [α]25/D 13°, c = 1 in H2O |
| Water Solubility | 0.1-1 g/100 mL at 23 ºC |
| Sensitive | Air & Light Sensitive |
| Merck | 13,6080 |
| BRN | 2417244 |
| Stability | Stable, but may be light sensitive. Very hygroscopic. Undergoes catalytic oxygenation in the presence of magnesium, cupric, cobalt, nickel and ferric ions. Store under a dry atmosphere. |
| CAS DataBase Reference | 41372-08-1(CAS DataBase Reference) |
| FDA UNII | 56LH93261Y |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P280-P305+P351+P338 | |||||||||
| Risk Statements | 20/21-36/37/38-42/43-65 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | YP2860000 | |||||||||
| F | 10-23 | |||||||||
| HS Code | 2922504500 | |||||||||
| NFPA 704 |
|
alpha-Methyldopa sesquihydrate price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2672 | Methyldopa PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial | 41372-08-1 | 1G | $334 | 2024-03-01 | Buy |
| Sigma-Aldrich | 857416 | (?)-3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine sesquihydrate 99% | 41372-08-1 | 5g | $77.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1426002 | Methyldopa United States Pharmacopeia (USP) Reference Standard | 41372-08-1 | 500mg | $802 | 2024-03-01 | Buy |
| Alfa Aesar | H56704 | (-)-3,4-Dihydroxy-alpha-methyl-L-phenylalanine sesquihydrate, 99% | 41372-08-1 | 1g | $14.65 | 2024-03-01 | Buy |
| Alfa Aesar | H56704 | (-)-3,4-Dihydroxy-alpha-methyl-L-phenylalanine sesquihydrate, 99% | 41372-08-1 | 5g | $49.65 | 2024-03-01 | Buy |
alpha-Methyldopa sesquihydrate Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Potent inhibitor of invertase and glucosidase inhibitor with a different specificity of action to DNJ and castanospermine. Inhibits glucosidase I.
Uses
Antihypertensive agent.
Biological Activity
l-(-)-α-methyldopa (hydrate) is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive.
Purification Methods
Recrystallise methyldopa from H2O. [Reinhold et al. J Org Chem 33 1209 1968.] The L-isomer forms a sesquihydrate from H2O m 302-304o (dec), and the anhydrous crystals are hygroscopic,[] 23D -4.0o (c 1, 0.1N HCl), []546 +154.5o (c 5, CuSO4 solution). It has max at 281nm ( 2780). Its solubility in H2O at 25o is ~10mg/mL and the pH of an aqueous solution is ~5.0. It is insoluble in most organic solvents. [Stein et al. J Am Chem Soc 77 700 1955, Beilstein 4 IV 2505.]
alpha-Methyldopa sesquihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 281)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| APOLLO HEALTHCARE RESOURCES | +6596580999 | sales@apollo-healthcare.com.sg | Singapore | 400 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Casorganics US Corp | +17326109938 | sales@casorganics.com | CHINA | 174 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12457 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
View Lastest Price from alpha-Methyldopa sesquihydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-06 | alpha-Methyldopa sesquihydrate
41372-08-1
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. | |
 |
2023-02-13 | Methyldopa Sesquihydrate
41372-08-1
|
US $80.00 / kg | 1kg | 99% | 100MT | Hebei baicao biology science and technology co., ltd | |
 |
2023-01-31 | alpha-Methyldopa sesquihydrate
41372-08-1
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
-
- alpha-Methyldopa sesquihydrate
41372-08-1
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
-
- Methyldopa Sesquihydrate
41372-08-1
- US $80.00 / kg
- 99%
- Hebei baicao biology science and technology co., ltd
-
- alpha-Methyldopa sesquihydrate
41372-08-1
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
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**DISCONTINUED**
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