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Eltrombopag

Eltrombopag
Eltrombopag
CAS No.
496775-61-2
Chemical Name:
Eltrombopag
Synonyms
Promacta;Sb497115;Sb-497115;ltrombopag;Eltrombopag;Unii-S56D65xj9g;Eltrombopag Acid;Eltrombopag [inn];Eltrombopag Free Base;EltroMbopag (SB-497115-GR)
CBNumber:
CB71463423
Molecular Formula:
C25H22N4O4
Formula Weight:
442.47
MOL File:
496775-61-2.mol

Eltrombopag Properties

Melting point:
242-244°C
Density 
1.33
storage temp. 
-20°C Freezer, Under Inert Atmosphere

SAFETY

Eltrombopag price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13247 Eltrombopag ≥98% 496775-61-2 1mg $25 2018-11-13 Buy
Cayman Chemical 13247 Eltrombopag ≥98% 496775-61-2 5mg $69 2018-11-13 Buy
Cayman Chemical 13247 Eltrombopag ≥98% 496775-61-2 10mg $95 2018-11-13 Buy
Cayman Chemical 13247 Eltrombopag ≥98% 496775-61-2 25mg $175 2018-11-13 Buy

Eltrombopag Chemical Properties,Uses,Production

Chemical Properties

Orange to Red Solid

Uses

Eltrombopag (SB-497115-GR, Promacta, Revolade) is a small molecule agonist of the c-mpl (TpoR) receptor with an IC50 of 0.69 μM for the inhibition of hERG K+ channel tail current. In preclinical studies, the compound was shown to interact selectively with

Uses

An agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia

Definition

ChEBI: A hydrazine in which each nitrogen atom is substituted, one by a 3'-carboxy-2-hydroxy[1,1'-biphenyl]-3-yl group and the other by a 1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene group. A small molecule agonist of the c-mpl (TpoR) receptor (the physiological target of the hormone thrombopoietin), it has been developed as a medication for conditions that lead to thrombocytopenia (abnormally low platelet counts).

Eltrombopag Preparation Products And Raw materials

Raw materials

Preparation Products


Eltrombopag Suppliers

Global( 128)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19958 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22059 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20795 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070;product@chemlin.com.cn
product@chemlin.com.cn CHINA 3015 60
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 14297 60
Shanghai Arbor Chemical Co., Ltd.
021-60451682
021-60451683 act@arborchemical.com CHINA 905 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691
yklbiotech@163.com CHINA 295 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20001 58
Shanghai Boyle Chemical Co., Ltd.
86-21-57758967 sales@boylechem.com China 2930 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76

View Lastest Price from Eltrombopag manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-26 Eltrombopag
496775-61-2
US $10.00 / KG 1KG 98% 200KG career henan chemical co

496775-61-2(Eltrombopag)Related Search:


  • 3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid Eltrombopag
  • Eltrombopag 3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
  • Eltrombopag Acid
  • Eltrombopag Free Base
  • Eltrombopag
  • 3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
  • (1,1'-Biphenyl)-3-carboxylic acid, 3'-((2Z)-(1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene)hydrazino)-2'-hydroxy-
  • Eltrombopag [inn]
  • Promacta
  • (E)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydro
  • (Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydro
  • ltrombopag
  • Sb497115
  • Sb-497115
  • Unii-S56D65xj9g
  • (E)-3\'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2\'-hydroxybiphenyl-3-carboxylic acid
  • 3-(5-{2-[2-(3,4-diMethylphenyl)-5-Methyl-3-oxo-2,3-dihydro-1H-pyrazol-4-yl]hydrazin-1-ylidene}-6-oxocyclohexa-1,3-dien-1-yl)benzoic acid
  • EltroMbopag (SB-497115-GR)
  • (Z)-3'-(2-(1-(3,4-DiMethylphenyl)-3-Methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
  • (Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-
  • [1,1'-Biphenyl]-3-carboxylic acid, 3'-[2-[(2Z)-1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-
  • 496775-61-2
  • Agonist
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • 496755-61-2
  • Inhibitors
  • Pharmaceuticals
  • SB-497115-GR, Revolade, Promacta
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