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(+)-Ledene

(+)-Ledene structure

CAS No.: 21747-46-6

Chemical Name:: (+)-Ledene

Synonyms: (+)-LEDENE;(+)-Ledene;Viridflorene;Varidiflorene;LEDENE, (+)-(RG);Einecs 244-565-3;Guaiazulene Impurity 4;95.0% (sum of enantiomers, GC);(+)-LEDENE 95+% MIXTURE OF ISOMERS;(+)-Ledene >=95.0% (sum of enantiomers, GC)

CBNumber:: CB7153554

Molecular Formula:: C15H24

Molecular Weight:: 204.35

MDL Number:: MFCD00042613

MOL File:: 21747-46-6.mol

MSDS File:: SDS

Last updated:2023-10-27 16:58:12

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(+)-Ledene Properties

Melting point	269°C
Boiling point	268-270 °C (lit.)
Density	0.927 g/mL at 20 °C (lit.)
refractive index	n20/D 1.504
storage temp.	Refrigerator
solubility	Chloroform (Sparingly), Ethanol (Slightly)
form	Oil
color	Colourless
optical activity	[α]20/D +68±2°, c = 10% in ethanol
BRN	2554786
LogP	6.447 (est)
FDA UNII	236ZZ41F70

SAFETY

Risk and Safety Statements

Safety Statements	23-24/25
WGK Germany	3

(+)-Ledene price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	61770	(+)-Ledene ≥95.0% (sum of enantiomers, GC)	21747-46-6	250mg	$367	2023-06-20	Buy
TRC	L320070	(+)-Ledene	21747-46-6	5mg	$45	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0015052	(+)-LEDENE 95.00%	21747-46-6	250MG	$839.22	2021-12-16	Buy
AHH	MT-16357	(+)-Ledene 96%	21747-46-6	1g	$418	2021-12-16	Buy

Product number	Packaging	Price	Buy
61770	250mg	$367	Buy
L320070	5mg	$45	Buy
CHM0015052	250MG	$839.22	Buy
MT-16357	1g	$418	Buy

(+)-Ledene Chemical Properties,Uses,Production

Description

(+)-Ledene, also called leden or viridiflorene, is an organic compound that belongs to the group of 5, 10-cycloaromadendrane sesquiterpenoids. These compounds are derived from the aromadendrane skeleton through a cyclization reaction between carbon atoms 5 and 10. (+)-Ledene is mainly found in saliva and is considered to have low solubility in water and a relatively neutral nature. In cellular environments, (+)-ledene is predominantly present in the cell membrane (predicted based on logP) and cytoplasm.

Uses

(+)-Ledene is an essential oil that is synthesized by viridiflorene synthase. It has been studied as an antioxidant, antimicrobial, antibiofilm and to treat various cancers.

Definition

ChEBI: Viridiflorene is a carbotricyclic sesquiterpene obtained from several natural sources, including Australian Tea Tree oil (Melaleuca alternifolia.) It is a sesquiterpene and a carbotricyclic compound.

General Description

(+)-Ledene is a naturally occurring sesquiterpene that can be prepared from (+)-aromadendrene via isomerization.

References

[1] DUC N. TRAN Prof.??Dr. N C. Biomimetic Synthesis of (+)-Ledene, (+)-Viridiflorol, (?)-Palustrol, (+)-Spathulenol, and Psiguadial A, C, and D via the Platform Terpene (+)-Bicyclogermacrene[J]. Chemistry - A European Journal, 2014. DOI:10.1002/chem.201403082.
[2] S. L. GWALTNEY K. J S S T Sakata. Bridged to Fused Ring Interchange. Methodology for the Construction of Fused Cycloheptanes and Cyclooctanes. Total Syntheses of Ledol, Ledene, and Compressanolide[J]. The Journal of Organic Chemistry, 1996. DOI:10.1021/jo961005a.

(+)-Ledene Preparation Products And Raw materials

Raw materials

Preparation Products

(+)-Ledene Suppliers

Global( 46)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Shaanxi Didu New Materials Co. Ltd	+86-89586680 +86-13289823923	1026@dideu.com	China	9116	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49999	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006608290; 18621169109	market03@meryer.com	China	40241	62
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65

Supplier	Advantage
Shanghai Zheyan Biotech Co., Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Shaanxi Didu New Materials Co. Ltd	58
GIHI CHEMICALS CO.,LIMITED	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
BOC Sciences	65

21747-46-6((+)-Ledene)Related Search:

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Viridflorene (+)-Ledene >=95.0% (sum of enantiomers, GC) [1aR-(1aalpha,7alpha,7abeta,7balpha)]-1a,2,3,5,6,7,7a,7b-octahydro-1,1,4,7-tetramethyl-1H-cycloprop[e]azulene (1S,2R,3R,11R)-3,3,7,11-TETRAMETHYL-TRICYCLO[6.3.0.0(2.4)]UNDEC-7-ENE (+)-LEDENE (+)-LEDENE 95+% MIXTURE OF ISOMERS (1aR)-1a,2,3,5,6,7,7aα,7bβ-Octahydro-1,1,4,7β-tetramethyl-1H-cycloprop[e]azulene (1aR)-1aβ,2,3,5,6,7,7aα,7bβ-Octahydro-1,1,4,7β-tetramethyl-1H-cyclopropa[e]azulene (1Ar-(1aalpha,7alpha,7abeta,7balpha))-1A,2,3,5,6,7,7A,7B-octahydro-1,1,4,7-tetramethyl-1H-cycloprop(E)azulene Einecs 244-565-3 LEDENE, (+)-(RG) 1,1,4,7-Tetramethyl-1a,2,3,5,6,7,7a,7b-octahydro-1H-cyclopropa[e]azulene 1H-Cycloprop[e]azulene, 1a,2,3,5,6,7,7a,7b-octahydro-1,1,4,7-tetramethyl-, [1aR-(1aalpha,7alpha,7abeta,7balpha)]- Varidiflorene (1aS,7S,7aS,7bS)-1,1,4,7-tetramethyl-1a,2,3,5,6,7,7a,7b-octahydrocyclopropa[e]azulene 1H-Cycloprop[e]azulene, 1a,2,3,5,6,7,7a,7b-octahydro-1,1,4,7-tetramethyl-, (1aR,7R,7aS,7bR)- 95.0% (sum of enantiomers, GC) (+)-Ledene Guaiazulene Impurity 4 21747-46-6 Complex Molecules Asymmetric Synthesis Chiral Building Blocks