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BREVETOXIN B

CAS No.
79580-28-2
Chemical Name:
BREVETOXIN B
Synonyms
gb2;t4-7;btx-b;PBTX-2;GBTX-2;gb2toxin;toxint-34;t4-7toxin;BREVETOXIN B;BREVETOXIN 2
CBNumber:
CB7161922
Molecular Formula:
C50H70O14
Molecular Weight:
895.08
MDL Number:
MFCD00214092
MOL File:
79580-28-2.mol
MSDS File:
SDS
Last updated:2023-06-08 09:01:57

BREVETOXIN B Properties

Density 1.188±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility Ethyl Acetate: soluble
form A film
pka 13.72±0.70(Predicted)
FDA UNII 8WBN7K7T6Z

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H300+H310+H330
Precautionary statements  P260-P262-P264-P280-P302+P352+P310-P304+P340+P310
Hazard Codes  T+
Risk Statements  26/27/28
Safety Statements  22-36/37/39-45
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  XW5886000
HazardClass  6.1(a)
PackingGroup  I
NFPA 704
0
4 0

BREVETOXIN B price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 203732 Brevetoxin PbTx-2, Ptychodiscus brevis - CAS 79580-28-2 - Calbiochem Lipid-solublepolyetherneurotoxinthatbindstoNa+channelsonnervesandmusc 79580-28-2 100μg $712 2024-03-01 Buy
Cayman Chemical 10011498 Brevetoxin B ≥95% 79580-28-2 100μg $275 2024-03-01 Buy
Product number Packaging Price Buy
203732 100μg $712 Buy
10011498 100μg $275 Buy

BREVETOXIN B Chemical Properties,Uses,Production

Description

Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively. Brevetoxin B is ichthyotoxic at nanomolar concentrations and is responsible for an illness described as neurotoxic shellfish poisoning.

Definition

ChEBI: Brevetoxin B is a ciguatoxin.

85079-48-7
79580-28-2
Synthesis of BREVETOXIN B from BREVETOXIN PBTX-3

BREVETOXIN B Preparation Products And Raw materials

Raw materials

Preparation Products

BREVETOXIN B Suppliers

Global( 44)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58
Shenzhen Regent Biochemical Technology Co., Ltd. 0755-0755-85201366 18938635012 sales@regentsciences.com China 9287 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 9945 58
JinOu Biomedical (Nanjing) Co., Ltd. 13000000000 jinoupharma@163.com China 11732 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 czbjpharma@126.com China 18488 58
Naturewill Biotechnology Co., Ltd. 18113192475 18113192475 3157321941@qq.com China 5000 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
PBTX-2 brevetoxint34 btx-b gb2 gb2toxin t4-7 t4-7toxin toxint-34 BREVETOXIN 2 BREVETOXIN B BREVETOXIN PBTX-2 BREVETOXIN PBTX-2, PTYCHODISCUS BREVIS GBTX-2 Brevetoxinpbtx-2-20c 1H-Pyrano(2'',3'':5',6')pyrano(2',3':5,6)pyrano(3,2-B)pyrano(2'''''',3'''''':5''''',6''''')pyrano(2''''',3''''':5'''',6'''')pyrano(2'''',3'''':6''',7''')oxepino(2''',3''':6'',7'')oxepino(2'',3'':5',6')pyrano(2',3':5,6)pyrano(2,3-G)oxocin-3-propanal, 2,3,4A,5,5A,6A,9,9A,10A,11,11A,12A,13,14,14A,15A,16,16A,18,20A,21A,22,22A,23A,24,25,25A,26A,27,27A,28A,29,29A,30A-tetratriacontahydro-1-hydroxy-9A,13,20,21A,25A,26A,30A-heptamethyl-alpha-methylene-18-oxo-, (1S-(1alpha,3alpha,4aalpha,5aalpha,6aalpha,9aalpha,10aalpha, 11aalpha,12aalpha,13beta,14aalpha,15aalpha,16aalpha,20abeta, 21abeta,22abeta,23abet Gb 2 (gymnodinium) 79580-28-2 C30H22O12 C50H70O14 BioChemical Cell Signaling and Neuroscience Cell Biology Other Sodium Channel Modulators Voltage-gated Ion Channels Sodium Channel Modulators Ion Channels Monovalent Ion Channels