1H-Benzimidazole-4-carboxylic acid
- CAS No.
- 46006-36-4
- Chemical Name:
- 1H-Benzimidazole-4-carboxylic acid
- Synonyms
- 4-Carboxy-1H-benzimidazole;Benzimidazole-4-carboxylicacid;4-Benzimidazolecarboxylic acid;1H-BENZIMIDAZOLE-4-CARBOXYLIC ACID;1,3-Benzodiazole-4-carboxylic acid;1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID;benzimidazole-4-carboxylic acid HCl;1H-Benzimidazole-4-carboxylicacid97%;1H-benzo[d]imidazol-7-carboxylic acid;1H-1,3-benzodiazole-4-carboxylic acid
- CBNumber:
- CB7164877
- Molecular Formula:
- C8H6N2O2
- Molecular Weight:
- 162.15
- MDL Number:
- MFCD01823426
- MOL File:
- 46006-36-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1H-Benzimidazole-4-carboxylicAcid | B197883 | 100mg | $45 |
| 1H-Benzimidazole-4-carboxylicAcid | B197883 | 500mg | $65 |
| 1H-Benzimidazole-4-carboxylic acid | 027337 | 1g | $79 |
| Benzimidazole-4-carboxylic acid | FB05897 | 1g | $87.5 |
| 1H-Benzimidazole-7-carboxylicacid | W6385 | 250mg | $104 |
| More product size | |||
1H-Benzimidazole-4-carboxylic acid price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B197883 | 1H-Benzimidazole-4-carboxylicAcid | 46006-36-4 | 100mg | $45 | 2021-12-16 | Buy |
| TRC | B197883 | 1H-Benzimidazole-4-carboxylicAcid | 46006-36-4 | 500mg | $65 | 2021-12-16 | Buy |
| Matrix Scientific | 027337 | 1H-Benzimidazole-4-carboxylic acid | 46006-36-4 | 1g | $79 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB05897 | Benzimidazole-4-carboxylic acid | 46006-36-4 | 1g | $87.5 | 2021-12-16 | Buy |
| AK Scientific | W6385 | 1H-Benzimidazole-7-carboxylicacid | 46006-36-4 | 250mg | $104 | 2021-12-16 | Buy |
1H-Benzimidazole-4-carboxylic acid Chemical Properties,Uses,Production
Synthesis
64-18-6
603-81-6
46006-36-4
To a 4M hydrochloric acid (20 mL) solution of formic acid (0.75 mL, 20.0 mmol) was added 2,3-diaminobenzoic acid (1.00 g, 6.6 mmol). The reaction mixture was heated at reflux temperature for 2 h and subsequently cooled to room temperature. The resulting pink precipitate was separated by filtration and dissolved in hot methanol. Decolorization was carried out by adding activated carbon and stirring for 10 min. The suspension was filtered and the solvent was evaporated under reduced pressure to afford benzimidazole-7-carboxylic acid (0.542 g, 51% yield) as white crystals with a melting point of 266-268 °C. The structure of the product was analyzed by 1H NMR (300 MHz, DMSO-d6) δ 9.64 (s, 1H), 8.11 (dd, J = 8.2, 0.9 Hz, 1H), 8.07 (dd, J = 7.6, 0.9 Hz, 1H), 7.65 (dd, J = 8.2, 7.6 Hz, 1H) and 13C NMR (75 MHz, DMSO-d6 ) δ 265.2, 142.0, 132.3, 129.3, 127.6, 125.6, 119.7, 117.6 confirmed.
References
[1] Journal of Medicinal Chemistry, 2000, vol. 43, # 22, p. 4084 - 4097
[2] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 14, p. 3933 - 3937
[3] Chemische Berichte, 1901, vol. 34, p. 905
[4] Patent: WO2018/42362, 2018, A1. Location in patent: Page/Page column 50
1H-Benzimidazole-4-carboxylic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29798 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Nanjing Hengbei Chemicals Co., Ltd. | +86-25-58393656 | sales@hengbeichem.cn | China | 6854 | 58 |
View Lastest Price from 1H-Benzimidazole-4-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-03-24 | 1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID
46006-36-4
|
US $3.00 / KG | 1KG | 98% | 200KG | Career Henan Chemical Co |
-
- 1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID
46006-36-4
- US $3.00 / KG
- 98%
- Career Henan Chemical Co
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