1H-Benzimidazole-4-carboxylic acid
- CAS No.
- 46006-36-4
- Chemical Name:
- 1H-Benzimidazole-4-carboxylic acid
- Synonyms
- 1H-benzo[d]imidazole-4-carboxylic acid;1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID;4-Carboxy-1H-benzimidazole;Benzimidazole-4-carboxylicacid;4-Benzimidazolecarboxylic acid;1,3-Benzodiazole-4-carboxylic acid;1H-BENZIMIDAZOLE-4-CARBOXYLIC ACID;benzimidazole-4-carboxylic acid HCl;1H-Benzimidazole-4-carboxylicacid97%;1H-benzo[d]imidazol-7-carboxylic acid
- CBNumber:
- CB7164877
- Molecular Formula:
- C8H6N2O2
- Molecular Weight:
- 162.15
- MDL Number:
- MFCD01823426
- MOL File:
- 46006-36-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
1H-Benzimidazole-4-carboxylic acid price More Price(66)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 261685 | Benzimidazole-4-carboxylic acid Asreported | 46006-36-4 | 500mg | $545 | 2026-06-03 | Buy |
| Usbiological | 261685 | Benzimidazole-4-carboxylic acid Asreported | 46006-36-4 | 1g | $839 | 2026-06-03 | Buy |
| Usbiological | 261685 | Benzimidazole-4-carboxylic acid Asreported | 46006-36-4 | 2g | $1133 | 2026-06-03 | Buy |
| Usbiological | 261685 | Benzimidazole-4-carboxylic acid Asreported | 46006-36-4 | 5g | $1351 | 2026-06-03 | Buy |
| Usbiological | 261685 | Benzimidazole-4-carboxylic acid Asreported | 46006-36-4 | 10g | $2166 | 2026-06-03 | Buy |
1H-Benzimidazole-4-carboxylic acid Chemical Properties, Uses, Production
Synthesis
64-18-6
603-81-6
46006-36-4
To a 4M hydrochloric acid (20 mL) solution of formic acid (0.75 mL, 20.0 mmol) was added 2,3-diaminobenzoic acid (1.00 g, 6.6 mmol). The reaction mixture was heated at reflux temperature for 2 h and subsequently cooled to room temperature. The resulting pink precipitate was separated by filtration and dissolved in hot methanol. Decolorization was carried out by adding activated carbon and stirring for 10 min. The suspension was filtered and the solvent was evaporated under reduced pressure to afford benzimidazole-7-carboxylic acid (0.542 g, 51% yield) as white crystals with a melting point of 266-268 °C. The structure of the product was analyzed by 1H NMR (300 MHz, DMSO-d6) δ 9.64 (s, 1H), 8.11 (dd, J = 8.2, 0.9 Hz, 1H), 8.07 (dd, J = 7.6, 0.9 Hz, 1H), 7.65 (dd, J = 8.2, 7.6 Hz, 1H) and 13C NMR (75 MHz, DMSO-d6 ) δ 265.2, 142.0, 132.3, 129.3, 127.6, 125.6, 119.7, 117.6 confirmed.
References
[1] Journal of Medicinal Chemistry, 2000, vol. 43, # 22, p. 4084 - 4097
[2] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 14, p. 3933 - 3937
[3] Chemische Berichte, 1901, vol. 34, p. 905
[4] Patent: WO2018/42362, 2018, A1. Location in patent: Page/Page column 50
1H-Benzimidazole-4-carboxylic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9409 | 55 |
| Carbott PharmTech Inc. | 0535-6385396 | info@carbottpharm.com | China | 996 | 56 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| ZEROSCHEM.CO.,LTD. | 10-61256048 13810278579; | sales@zeroschem.com | China | 1405 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16307 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
View Latest Price from 1H-Benzimidazole-4-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-03-24 | 1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID
46006-36-4
|
$3.00 | 1KG | 98% | 200KG | Career Henan Chemical Co |
-
- 1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID
46006-36-4
- $3.00
- 98%
- Career Henan Chemical Co
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