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Isobutyl chloroformate

Isobutyl chloroformate
Isobutyl chloroformate structure
CAS No.
543-27-1
Chemical Name:
Isobutyl chloroformate
Synonyms
IBCF;oroformate;isobutyl chloformate;Isobutyl chloroforma;ISOBUTYL CHLOROFORMATE;isobutyl chlrorformate;Isobuthyl chloroforMate;Isobutyl chloocarbonate;ISOBUTYL CHLOROCARBONATE;Isobutylchloroformate99%
CBNumber:
CB7165612
Molecular Formula:
C5H9ClO2
Formula Weight:
136.58
MOL File:
543-27-1.mol

Isobutyl chloroformate Properties

Melting point:
-80°C
Boiling point:
128.8 °C(lit.)
Density 
1.053 g/mL at 25 °C(lit.)
vapor pressure 
0.33 mm Hg ( 20 °C)
refractive index 
n20/D 1.407(lit.)
Flash point:
82 °F
storage temp. 
2-8°C
solubility 
benzene: miscible
form 
Liquid
color 
Clear
Water Solubility 
Immiscible with water.
Sensitive 
Moisture Sensitive
Merck 
14,5139
BRN 
956590
CAS DataBase Reference
543-27-1(CAS DataBase Reference)
FDA UNII
6S785TC0OB
NIST Chemistry Reference
Isobutyl chloroformate(543-27-1)
EPA Substance Registry System
Isobutyl chloroformate (543-27-1)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS02,GHS05,GHS06
Signal word  Danger
Hazard statements  H300-H310-H318-H330-H226-H302-H314-H331
Precautionary statements  P261-P280-P305+P351+P338-P310-P301+P310a-P303+P361+P353-P304+P340-P320-P405-P501a
Hazard Codes  T
Risk Statements  10-22-23-34
Safety Statements  26-36/37/39-45
RIDADR  UN 3390 6.1/PG 1
WGK Germany  2
10-19
TSCA  Yes
HazardClass  6.1
PackingGroup  I
HS Code  29159000
Toxicity LD50 orally in Rabbit: 1400 mg/kg

Isobutyl chloroformate price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 177989 Isobutyl chloroformate 98% 543-27-1 100g $34.4 2021-03-22 Buy
Sigma-Aldrich 8.02358 Isobutyl chloroformate for synthesis 543-27-1 100 mL $35.24 2021-03-22 Buy
Sigma-Aldrich 177989 Isobutyl chloroformate 98% 543-27-1 25g $27.3 2021-03-22 Buy
Sigma-Aldrich 8.02358 Isobutyl chloroformate for synthesis 543-27-1 2.5 L $387.57 2021-03-22 Buy
Alfa Aesar A14692 Isobutyl chloroformate, 98% 543-27-1 100g $32.7 2021-03-22 Buy

Isobutyl chloroformate Chemical Properties,Uses,Production

Chemical Properties

clear liquid

Chemical Properties

A combustible, colorless to light-colored liquid.

Uses

Peptide reagent.

General Description

A colorless to light-colored liquid. Insoluble in water and denser than water. Very corrosive to skin, eyes, and mucous membranes. Very toxic by ingestion, inhalation and skin absorption. Combustible.

Air & Water Reactions

Highly flammable. Insoluble in water. Reacts with moisture in the air to produce highly corrosive and toxic fumes of hydrogen chloride gas. Decomposes exothermically in water.

Reactivity Profile

Isobutyl chloroformate is incompatible with water, with strong oxidizing agents, alcohols, bases (including amines). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Hazard

Flammable. Corrosive.

Health Hazard

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Bromoacetates and chloroacetates are extremely irritating/lachrymators. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Potential Exposure

This is a high volume chemical with production exceeding 1 million pounds annually in the U.S . No specific use found

Shipping

UN2742 Chloroformates, toxic, corrosive, flammable, n.o.s., Hazard class: 6.1; Labels: 6.1—Poison Inhalation Hazard, 8—Corrosive material; 3—Flammable liquid; Technical Name Required, Potential Inhalation Hazard (Special Provision 5). PG II. UN3390 Toxic by inhalation liquid, corrosive, n.o.s. with an LC50 # 1000 mL/m3 and saturated vapor concentration ≥ 10 LC50, Hazard Class: 6.1; Labels: 6.1—Poisonous materials, 8—Corrosive material, Technical Name Required, Inhalation Hazard Zone B

Purification Methods

It can be dried over CaCl2 and fractionated at atmospheric pressure while keeping moisture out. Its purity can be checked by conversion to the phenyl urethane derivative with PhNCO [Saunders et al. J Am Chem Soc 73 3796 1951.] IR: 1780cm-1 [Thompson & Jameson Spectrochim Acta 13 236 1959, R.se JustusLiebigs Ann Chem 205 227 1880]. [Beilstein 3 IV 26.]

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, alcohols, ethers, amines. Forms explosive mixture with air above flash point (27C). Compounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water and a salt that may be harmful. Incompatible with arsenic compounds (releases hydrogen cyanide gas), diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides (releasing heat, toxic and possibly flammable gases), thiosulfates and dithionites (releasing hydrogen sulfate and oxides of sulfur). Decomposes exothermically in water. Reacts with moisture in air to produce highly corrosive and toxic fumes of hydrogen chloride gas

Waste Disposal

Disposal of unused product must be undertaken by qualified personnel who are knowledgeable in all applicable regulations and follow all pertinent safety precautions including the use of appropriate protective equipment. For proper handling and disposal, always comply with federal, state, and local regulations.

Isobutyl chloroformate Preparation Products And Raw materials

Raw materials

Preparation Products


Isobutyl chloroformate Suppliers

Global( 209)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2941 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6369 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23035 58
Changzhou Carman Chemical Co., Ltd.
15061933924
jane@carmanchem.com; catal@carmanchem.com CHINA 514 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
HENAN BON INDUSTRIAL CO.,LTD
0371-55170695
info@hnbon.com CHINA 26742 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47498 58
career henan chemical co
13203830695 0086-371-86658258
0086-371-86658258 factory@coreychem.com CHINA 29864 58
SIMAGCHEM CORP
13806087780 +86 13806087780
shaobowang@simagchem.com CHINA 17453 58
Hubei Ipure Biology Co., Ltd
+8618062405514
18062427325 ada@ipurechemical.com;ada@ipurechemical.com China 10352 58

View Lastest Price from Isobutyl chloroformate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-01-09 Isobutyl chloroformate
543-27-1
US $9.80 / KG 1g ≥99% 100kg Career Henan Chemical Co

Isobutyl chloroformate Spectrum


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