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Tiamulin

Tiamulin
Tiamulin structure
CAS No.
55297-95-5
Chemical Name:
Tiamulin
Synonyms
C12065;sq14055;tiavetp;TIAMILIN;TIAMULIN;Tiamutin;tiamulina;thiamutilin;Tiamulin (100 mg);TiaMulin fuMerate API
CBNumber:
CB7171536
Molecular Formula:
C28H47NO4S
Formula Weight:
493.74
MOL File:
55297-95-5.mol

Tiamulin Properties

Melting point:
147.5°C
Density 
1.0160 (rough estimate)
refractive index 
1.6550 (estimate)
form 
neat
CAS DataBase Reference
55297-95-5(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
WGK Germany  2
RTECS  AG9552000
Hazardous Substances Data 55297-95-5(Hazardous Substances Data)
Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:

Tiamulin price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 34044 Tiamulin VETRANAL 55297-95-5 100mg-r $200 2018-11-20 Buy
Sigma-Aldrich 1667355 Tiamulin United States Pharmacopeia (USP) Reference Standard 55297-95-5 100mg $352.8 2018-11-20 Buy

Tiamulin Chemical Properties,Uses,Production

Uses

Tiamulin is a semi–synthetic analogue of pleuromutilin in which the hydroxyacetyl side chain is replaced with a larger diethylaminoethylthioacetyl moiety, providing greater hydrophobicity and an ionisable group for salt formation and greater water solubility. Tiamulin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action. Like pleuromutilin, it inhibits protein synthesis by binding to domain V of 23S rRNA.

Definition

ChEBI: A carbotricyclic compound that is pleuromutilin in which the hydroxyacetate group is replaced by a 2-{[2-(diethylamino)ethyl]sulfanyl}acetate group. An antibacterial drug, tiamulin is used in veterinary medicine (generally as its hydrogen fumarate salt) fo the treatment of swine dysentery caused by Serpulina hyodysenteriae.

Safety Profile

Poison by intramuscular and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of SOx and NOx. See also MERCAPTANS.

Veterinary Drugs and Treatments

Tiamulin is approved for use in swine to treat pneumonia caused by susceptible strains of Haemophilus pleuropneumoniae and swine dysentery caused by Treponema hyodysenteriae. As a feed additive, it is used to cause increased weight gain in swine.

Tiamulin Preparation Products And Raw materials

Raw materials

Preparation Products


Tiamulin Suppliers

Global( 80)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21935 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20676 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32452 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23958 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20084 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8266 58
BEST-REAGENT 400-1166-196 18981987031
028-84555506 QQ:800101999 cdhxsj@163.com China 9903 57
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123
86-21-63290778 86-21-63218885 sj_scrc@sinopharm.com China 9851 79
BOC Sciences
info@bocsci.com United States 10507 65

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