ChemicalBook >> CAS DataBase List >>18alpha-Glycyrrhetinic acid
18alpha-Glycyrrhetinic acid
- CAS No.
- 1449-05-4
- Chemical Name:
- 18alpha-Glycyrrhetinic acid
- Synonyms
- Nsc 35350;Triterpene;Ccris 3963;Brn 2956366;Einecs 215-907-9;18α-Glycyrrhetinic;18a-Glycyrrhetic acid;18α-Glycyrrhetic acid;18A-GLYCYRRHETINIC ACID;beta-glycyrrhetinicacid
- CBNumber:
- CB7172205
- Molecular Formula:
- C30H46O4
- Molecular Weight:
- 470.68
- MDL Number:
- MFCD00064897
- MOL File:
- 1449-05-4.mol
- MSDS File:
- SDS
Last updated:2023-05-25 18:01:17
| Melting point | 331-333°C |
|---|---|
| Boiling point | 492.11°C (rough estimate) |
| Density | 0.9967 (rough estimate) |
| refractive index | 1.4800 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 4.71±0.70(Predicted) |
| color | White to Off-White |
| LogP | 6.570 (est) |
| CAS DataBase Reference | 1449-05-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | X6NYL2CP2E |
18alpha-Glycyrrhetinic acid price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | G8503 | 18α-Glycyrrhetinic acid ≥95% | 1449-05-4 | 250mg | $114 | 2024-03-01 | Buy |
| Sigma-Aldrich | G8503 | 18α-Glycyrrhetinic acid ≥95% | 1449-05-4 | 1g | $254.4 | 2024-03-01 | Buy |
| Usbiological | 412321 | 18α-Glycyrrhetinic Acid | 1449-05-4 | 100mg | $460 | 2021-12-16 | Buy |
| TRC | G735005 | 18α-Glycyrrhetinic acid | 1449-05-4 | 500mg | $660 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0017607 | 18ALPHA-GLYCYRRHETINIC ACID 95.00% | 1449-05-4 | 1G | $973.84 | 2021-12-16 | Buy |
18alpha-Glycyrrhetinic acid Chemical Properties,Uses,Production
Chemical Properties
Glycyrrhetinic acid is a kind of glycoside composed of glycyrrhizic acid-ff two molecules glucuronic acid. It appears as white crystalline powder with sweet taste. The sweetness is about 200 times of the sucrose. Its sweetness is different from other sweeteners such as sucrose. After eating, you can sense the sweetness only after a few moments but the retention time is long. Combination of a small amount of glycyrrhizin and sucrose can save 20% sucrose without affecting the sweetness. Although having no aroma, it has incense effect. It has a melting point (decomposition) of 220 ° C. The aqueous solution is weakly acidic and can be treated by acid.
Uses
Sweeteners; sweetness improving agents; flavor enhancers (dairy products, cocoa products, egg products, mutton), flavoring agents (function well especially when used in combination with salt), Chinese folk mostly use it in sauce and sauce products, pickled goods and so on.
Uses
18α-Glycyrrhetinic acid may be used to synthesize:
- 3-keto-18α-glycyrrhetinic acid
- methyl esters of 18α-glycyrrhetinic acid
- methyl esters of 3-keto-18α-glycyrrhetinic acid
General Description
18α-Glycyrrhetinic acid (18α-GA) is a bioactive triterpenoid found in licorice. It shows selective inhibition of 11-HSD1 (11-hydroxysteroid dehydrogenase 1). It also shows anti-proliferative and apoptotic effect on hepatic stellate cells (HSCs).
18alpha-Glycyrrhetinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 181)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 | sale02@cqherb.com | CHINA | 376 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
View Lastest Price from 18alpha-Glycyrrhetinic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-02-14 | Glycyrrhetinic acid 1449-05-4
1449-05-4
|
US $7.50 / mg | 20mg | ≥98% | 1000.00 kgs | NanJing Spring & Autumn Biological Engineering CO., LTD. | |
 |
2021-07-13 | 18alpha-Glycyrrhetinic acid
1449-05-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-09 | 18alpha-Glycyrrhetinic acid
1449-05-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Glycyrrhetinic acid 1449-05-4
1449-05-4
- US $7.50 / mg
- ≥98%
- NanJing Spring & Autumn Biological Engineering CO., LTD.
-
- 18alpha-Glycyrrhetinic acid
1449-05-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 18alpha-Glycyrrhetinic acid
1449-05-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
1449-05-4(18alpha-Glycyrrhetinic acid)Related Search:
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18alpha-Glycyrrhetinic acid
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Diammonium glycyrrhizinate
trans-4-Hexylcyclohexanecarboxylic acid
3,5-Dimethyl-2-cyclohexen-1-one
PIPERITONE
1of4
3-beta-hydroxy-11-oxo-18-alpha-olean-12-en-30-oicaci
3-beta-hydroxy-11-oxo-18-alpha-olean-12-en-30-oicacid
beta-glycyrrhetinicacid
GLYCYRRHETINIC ACID, 18A-
3BETA-HYDROXY-11-OXO-18ALPHA,20BETA-OLEAN-12-EN-29-OIC ACID
18A-GLYCYRRHETINIC ACID
18ALPHA-GLYCYRRHETINIC ACID
Triterpene
Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3.beta.,18.alpha.,20.beta.)-
(18α)-3β-Hydroxy-11-oxoolean-12-en-30-oic acid
3β-hydroxy-11-oxo-18α,20β-olean-12-en-29-oic acid
18-ISOGLYCYRRHETINICACID
18-ALPHA-GLYCYRRHETICACID
(3beta,18alpha,20beta)-3-Hydroxy-11-oxoolean-12-en-29-oic acid
18α-Glycyrrhetinic
18-alpha-Olean-12-en-30-oic acid, 3-beta-hydroxy-11-oxo-
Brn 2956366
Ccris 3963
Einecs 215-907-9
Nsc 35350
18a-Glycyrrhetic acid
18alpha-Glycyrrhetinic acid >=95%
Glycyrrhetinic acid (α-type)
18α-Glycyrrhetinic acid, 95%, from Glycyrrhiza uralensis Fisch.
Glycyrrhetinic acid 1449-05-4
18a-Glycyrrhetic acid,95%
18α-Glycyrrhetinic Acid,HPLC≥98%
Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,18α,20β)-
Enoxolone EP Impurity A
18α-Glycyrrhetinic Acid
Enoxolone Impurity 1 (Enoxolone EP Impurity A)
(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bS)-10-hy droxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3 ,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-ic osahydropicene-2-carboxylic acid
18α-Glycyrrhetic acid
18 α-glycyrrhetintic acid
Magnesium Isoglycyrrhetinic Acid Impurity C
1449-05-4
Chiral Building Blocks
Asymmetric Synthesis
Complex Molecules
Inhibitors
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract
sy
The group of Liquorice
Tri-Terpenoids