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3-Bromopropionic acid

CAS No.
590-92-1
Chemical Name:
3-Bromopropionic acid
Synonyms
3-Bromopropanoic acid;3-Bromoprpionicacid;-Bromopropionicacid;RARECHEM AL BO 0160;3-bromopropanoicacid;3-bromo-propanoicaci;3-bromo-propionicaci;3-BROMPROPIONIC ACID;3-bromo-Propanoicacid;SS-BROMOPROPIONICACID
CBNumber:
CB7177280
Molecular Formula:
C3H5BrO2
Molecular Weight:
152.97
MDL Number:
MFCD00002763
MOL File:
590-92-1.mol
MSDS File:
SDS
Modify Date:
2022-08-11 17:35:50

3-Bromopropionic acid Properties

Melting point 58-62 °C(lit.)
Boiling point 140-142 °C (45 mmHg)
Density 1.48 g/mL at 25 °C(lit.)
refractive index 1.4753 (estimate)
Flash point 150 °F
storage temp. 2-8°C
solubility H2O: 0.1 g/mL, clear
form Crystals or Crystalline Powder
pka 4.00(at 25℃)
color White to slightly yellow
Water Solubility 0.1 g/mL
Merck 14,1433
BRN 1071333
CAS DataBase Reference 590-92-1(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII WFZ7CSR69R
NIST Chemistry Reference Propanoic acid, 3-bromo-(590-92-1)
EPA Substance Registry System Propanoic acid, 3-bromo- (590-92-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
Hazard Codes  F,C
Risk Statements  11-34
Safety Statements  26-36/37/39-45
RIDADR  UN 3261 8/PG 2
WGK Germany  3
RTECS  UE7875000
Hazard Note  Corrosive/Highly Flammable
TSCA  Yes
HazardClass  4.1
PackingGroup  III
HS Code  29159080

3-Bromopropionic acid price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 101281 3-Bromopropionic acid 97% 590-92-1 100g $61.3 2022-05-15 Buy
TCI Chemical B0645 3-Bromopropionic Acid >98.0%(GC)(T) 590-92-1 25g $23 2022-04-27 Buy
TCI Chemical B0645 3-Bromopropionic Acid >98.0%(GC)(T) 590-92-1 100g $45 2022-04-27 Buy
Alfa Aesar A11573 3-Bromopropionic acid, 97% 590-92-1 25g $24.1 2022-04-27 Buy
Alfa Aesar A11573 3-Bromopropionic acid, 97% 590-92-1 100g $36.6 2022-04-27 Buy
Product number Packaging Price Buy
101281 100g $61.3 Buy
B0645 25g $23 Buy
B0645 100g $45 Buy
A11573 25g $24.1 Buy
A11573 100g $36.6 Buy

3-Bromopropionic acid Chemical Properties,Uses,Production

Chemical Properties

white to pale yellow or orange crystalline. soluble in water, alcohol, ether, chloroform, benzene. Hydrolysis in alkaline solution generates hydroxypropionic acid. Corrosive. for organic synthesis.

Uses

3-Bromopropionic acid used as quaternization agent in amperometric biosensors.

Application

3-Bromopropionic acid is a widely used chemical intermediate. It can be used as a starting material to synthesize derivatives such as esters, acid halides and amides; the active group bromine can undergo a series of reactions, and is mainly used in the fields of pesticides and medicines. Such as the pesticides diflufenacil, furalax and so on.

Preparation

3-Bromopropionic acid is prepared by reacting acrylonitrile with hydrogen bromide to obtain bromopropionitrile and then hydrolyzing it. Add acrylonitrile to boiling hydrobromic acid, reflux at 130°C for 6 hours, extract the solid obtained by filtration with ethanol, and obtain the crude product after recovering ethanol by distillation under reduced pressure. By heating 2-cyanoethanol and 40% hydrobromic acid to reflux for 2h, 3-bromopropionic acid can also be produced with a yield of over 80%.

Synthesis Reference(s)

Journal of the American Chemical Society, 71, p. 2807, 1949 DOI: 10.1021/ja01176a061
Organic Syntheses, Coll. Vol. 1, p. 131, 1941

Safety Profile

Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of Br-. See also BROMIDES.

Purification Methods

The acid crystallises as plates from CCl4. It is soluble in organic solvents and H2O. Its methyl ester has b 65o/18mm and 80o/27mm. The S-benzylisothiouronium salt has m 136o. [Kendall & McKenzie Org Synth Coll Vol I 131 1941, Beilstein 2 IV 764.]

598-72-1
590-92-1
Synthesis of 3-Bromopropionic acid from 2-Bromopropionic acid
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View Lastest Price from 3-Bromopropionic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2019-08-08 3-Bromopropionic acid
590-92-1
US $1.00 / KG 1KG 98% 100KG Career Henan Chemical Co
2-Carboxyethyl bromide 2-carboxyethylbromide 3-bromo-propanoicaci 3-bromopropanoicacid 3-bromo-Propanoicacid 3-bromo-propionicaci 3-Bromopropionicacid,98% BETA-BROMOPRIOPIONICACID SS-BROMOPROPIONICACID 3-BROMOPROPIONIC ACID (BETA-) 98+% 3-Bromopropionic acid ,99% 3 - broMine propionic acid 3-Bromopropionic acid,97% 3-BroMopropionic acid, 97% 100GR Propionic acid, 3-broMo- (6CI,7CI,8CI) Propionic acid, β-broMo- (2CI) 3-Bromoprpionicacid beta-bromopropanoicacid -Bromopropionicacid Propanoicacid,3-bromo- Propionic acid, 3-bromo- 3-BROMOPROPIONIC ACID 3-BROMPROPIONIC ACID BETA-BROMOPROPIONIC ACID B-BROMOPROPIONIC ACID RARECHEM AL BO 0160 3-Bromo propionic acd 3-Bromopropionic Acid (CAS No. : 590-92-1) 3-Bromopropionic Acid > 3-Bromopropanoic acid 590-92-1 CH2BrCH2COOH BrCH2CH2CO2H C3H5O2BR CARBOXYLIC ACID Organic Building Blocks 蠅-Functional Alkanols, Carboxylic Acids, Amines & Halides 蠅-Bromocarboxylic Acids C1 to C5 Carbonyl Compounds Carboxylic Acids Building Blocks Aromatic Propionic Acids Organic acids Pyridines derivates omega-Bromocarboxylic Acids omega-Functional Alkanols, Carboxylic Acids, Amines & Halides C1 to C5 Carbonyl Compounds Carboxylic Acids