ChemicalBook >> CAS DataBase List >>H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH

H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH

H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH structure

CAS No.: 117399-93-6

Chemical Name:: H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH

Synonyms: et-3;EDN3;HSCR4;human,rat;ET-3, HUMAN;ENDOTHELIN-3;Rat endothelin-3;ET-3 (HUMAN, RAT);Endothelin 3【rat】;Human endothelin-3

CBNumber:: CB7181630

Molecular Formula:: C121H168N26O33S4

Molecular Weight:: 2643.04

MDL Number:: MFCD00076378

MOL File:: 117399-93-6.mol

Last updated:2023-06-30 15:45:59

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H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH Properties

Density	1.285±0.06 g/cm3(Predicted)
storage temp.	−20°C
form	powder
color	white
Water Solubility	Soluble to 1 mg/ml in water
FDA UNII	0066WLJ02E

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H300+H330
Precautionary statements	P301+P310+P330-P304+P340+P310
Safety Statements	22
WGK Germany	3
F	3-10

H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	E9137	Endothelin 3 human, rat ≥97%(HPLC),powder	117399-93-6	10μg	$127	2024-03-01	Buy
Sigma-Aldrich	E9137	Endothelin 3 human, rat ≥97%(HPLC),powder	117399-93-6	50μg	$226.2	2024-03-01	Buy
Sigma-Aldrich	E9137	Endothelin 3 human, rat ≥97%(HPLC),powder	117399-93-6	0.1mg	$679	2024-03-01	Buy
Sigma-Aldrich	05-23-3801	Endothelin 3, Human and Rat Attenuates thrombin-evoked aggregation of human platelets.	117399-93-6	0.5MG	$509	2024-03-01	Buy
Sigma-Aldrich	05-23-3801	Endothelin 3, Human and Rat - CAS 117399-93-6 - Calbiochem Attenuates thrombin-evoked aggregation of human platelets.	117399-93-6	.5mg	$487	2023-01-07	Buy

Product number	Packaging	Price	Buy
E9137	10μg	$127	Buy
E9137	50μg	$226.2	Buy
E9137	0.1mg	$679	Buy
05-23-3801	0.5MG	$509	Buy
05-23-3801	.5mg	$487	Buy

H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH Chemical Properties,Uses,Production

Uses

Endothelin 3 human, rat has been used for culturing neural tube explant culture, and the pharmacological study of endothelin receptors.

General Description

Endothelin 3 (ET3) belongs to endothelin peptide family, which includes three members, ET-1, -2 and -3. These are 21-amino acid peptides, which are synthesized as precursors. They are converted to biologically active peptides, after being cleaved by proteases. There are two endothelin receptors called ETRA and ETRB, and ET3 binds to ETRB. It is localized to human intestine and colon.

Biochem/physiol Actions

Endothelin 3 (ET3) is a vasoconstrictor that acts in a paracrine and autocrine manner, and in intestinal lamina propria causes the degranulation of mast cells. It results in the release of ions from intestinal epithelial cells. In acute and chronic intestinal inflammation, it is overexpressed. It is also up-regulated in colon carcinoma, where it supports cell proliferation and survival. It might be involved in colon homeostasis, and is essential for the survival and proliferation of goblet cells. In mice, it is essential for the development of pigment cells derived from neural crest (NC). Its expression is de-regulated in metastatic melanoma.

storage

Store at -20°C

H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH Preparation Products And Raw materials

Raw materials

Preparation Products

H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH Suppliers

Global( 107)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Cellmano Biotech Limited	0551-65326643 18156095617	info@cellmano.com	China	999	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29474	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
Hangzhou Go Top Peptide Biotech	0571-88211921	sales1@gotopbio.com	CHINA	2609	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58

Supplier	Advantage
Hubei Jusheng Technology Co.,Ltd.	58
BOC Sciences	58
Cellmano Biotech Limited	58
career henan chemical co	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
Hangzhou Go Top Peptide Biotech	58
Alfa Chemistry	58
Chengdu Youngshe Chemical Co., Ltd.	58
TargetMol Chemicals Inc.	58

View Lastest Price from H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-02-13	H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH 117399-93-6	US $7.00 / KG	1KG	99%	100KG	Career Henan Chemical Co
	2020-02-13	H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH 117399-93-6	US $7.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
117399-93-6
US $7.00 / KG
99%
Career Henan Chemical Co

H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
117399-93-6
US $7.00 / KG
99%
Career Henan Chemical Co

117399-93-6(H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH)Related Search:

IRL-1038 Endothelin-1 (human, porcine) H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH BIG ET-1 (1-38) (HUMAN) ENDOTHELIN (16-21)

GLYCYL-L-TRYPTOPHAN H-VAL-TRP-OH H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH N-ACETYL-L-HISTIDINE METHYL AMIDE H-ILE-ALA-OH

GLYCYL-DL-TRYPTOPHAN H-LEU-BETA-ALA-OH H-GLY-GLY-TRP-OH H-VAL-GLY-GLY-OH L-ALANYL-L-TRYPTOPHAN

H-ILE-TRP-OH AC-PHE-TYR-NH2 H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH

1of4

ENDOTHELIN-III, HUMAN, RAT ENDOTHELIN-3 ENDOTHELIN-3, HUMAN ENDOTHELIN 3, HUMAN AND RAT ENDOTHELIN-3 (HUMAN, MOUSE, RABBIT, RAT) ENDOTHELIN-3 (HUMAN) (PORCINE, RAT, RABBIT) ENDOTHELIN 3 HUMAN, RAT ENDOTHELIN-3 (HUMAN, RAT, PIG) ENDOTHELIN-3 (HUMAN, RAT, PORCINE, RABBIT) CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP HUMAN, RAT, PORCINE, RABBIT CTCFTYKDKECVYYCHLDIIW CTCFTYKDKECVYYCHLDIIW (DISULFIDE BRIDGE: 1-15 AND 3-11) H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH (DISULFIDE BRIDGE: 1-15 AND 3-11) ET-3, HUMAN ET-3, HUMAN AND RAT ET-3 (HUMAN, MOUSE, RABBIT, RAT) ET-3 (HUMAN, RAT) ET-3 (HUMAN, RAT, PIG) human,rat et-3 M.W. 2643.04 C121H168N26O33S4 Endothelin 3【canine】 Endothelin 3【rabbit】 Endothelin 3【rat】 CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR- TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP(DISULFIDE BRIDGE:CYS1-CYS15, CYS3-CYS11) CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP: CTCFTYKDKECVYYCHLDIIW DISULFIDE BRIDGES CYS1-CYS15, CYS3-CYS11 Endothelin-3 (huMan, Mouse, rabbit, rat) ET-3 (huMan, Mouse, rabbit, rat) Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridges Cys1-Cys15 and Cys3-Cys11) Endothelin 3 huMan, ratEndothelin Endothelin 3 (huMan)(9CI) Anti-EDN3 antibody produced in rabbit EDN3 HSCR4 ANTI-EDN3 (C-TERM) antibody produced in rabbit 19: PN: WO2007112069 SEQID: 10 claimed protein 33,34,49,50-Tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecaazabicyclo[23.22.4]henpentacontane, cyclic peptide deriv. Endothelin 3 (mouse intestine) Human endothelin-3 Rat endothelin-3 ENDOTHELIN 3, HUMAN, RAT, 50 UG* Endothelin 3, human, rat, ≥97% (HPLC), powder Endothelin 3, Human and Rat - CAS 117399-93-6 - Calbiochem Endothelin 3 (Rat,Human) L-Tryptophan, L-cysteinyl-L-threonyl-L-cysteinyl-L-phenylalanyl-L-threonyl-L-tyrosyl-L-lysyl-L-α-aspartyl-L-lysyl-L-α-glutamyl-L-cysteinyl-L-valyl-L-tyrosyl-L-tyrosyl-L-cysteinyl-L-histidyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-isoleucyl-, cyclic (1→15),(3→11)-bis(disulfide) H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH USP/EP/BP Endothelin 3 human, rat (TFA) 117399-93-6 C121H168N26O33S4 Agonist BioChemical Amino Acids and Peptides Biochemicals and Reagents Peptides Endothelins Peptide Endothelin receptor