ChemicalBook >> CAS DataBase List >>Homovanillic acid
Homovanillic acid
- CAS No.
- 306-08-1
- Chemical Name:
- Homovanillic acid
- Synonyms
- HVA;Homovanilic acid;4-HYDROXY-3-METHOXYPHENYLACETIC ACID;4-Hydroxy-3-methoxybenzeneacetic acid;Benzeneacetic acid, 4-hydroxy-3-methoxy-;JACS-306-08-1;homovanillicaci;Vanilacetic acid;HOMOVANIUIC ACID;HOMORANILLIC ACID
- CBNumber:
- CB7198081
- Molecular Formula:
- C9H10O4
- Molecular Weight:
- 182.17
- MDL Number:
- MFCD00004350
- MOL File:
- 306-08-1.mol
- MSDS File:
- SDS
Last updated:2023-10-16 17:43:51
| Melting point | 142-145 °C(lit.) |
|---|---|
| Boiling point | 235.56°C (rough estimate) |
| Density | 1.1634 (rough estimate) |
| refractive index | 1.4209 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Crystalline Powder |
| pka | 4.39±0.10(Predicted) |
| color | White to beige |
| Water Solubility | soluble |
| Merck | 14,4740 |
| BRN | 2213447 |
| Stability | Hygroscopic |
| LogP | 0.330 |
| CAS DataBase Reference | 306-08-1(CAS DataBase Reference) |
| FDA UNII | X77S6GMS36 |
| NIST Chemistry Reference | Benzeneacetic acid, 4-hydroxy-3-methoxy-(306-08-1) |
| EPA Substance Registry System | Homovanillic acid (306-08-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-23 | |||||||||
| TSCA | T | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29189900 | |||||||||
| NFPA 704 |
|
Homovanillic acid price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H1252 | Homovanillic acid Fluorimetric reagent | 306-08-1 | 1g | $92.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | 69673 | Homovanillic acid analytical standard | 306-08-1 | 25mg | $71.4 | 2024-03-01 | Buy |
| TCI Chemical | H0339 | 4-Hydroxy-3-methoxyphenylacetic Acid >98.0%(T) | 306-08-1 | 1g | $42 | 2024-03-01 | Buy |
| TCI Chemical | H0339 | 4-Hydroxy-3-methoxyphenylacetic Acid >98.0%(T) | 306-08-1 | 5g | $141 | 2024-03-01 | Buy |
| Alfa Aesar | A12441 | Homovanillic acid, 98+% | 306-08-1 | 1g | $72.4 | 2024-03-01 | Buy |
Homovanillic acid Chemical Properties,Uses,Production
Description
Homovanillic acid (HVA) is a dopamine metabolite. It is formed via deamination of dopamine by monoamine oxidase (MAO) to produce 3,4-dihydroxyphenylacetic acid (DOPAC; ) followed by DOPAC metabolism by catechol-O-methyltransferase (COMT). HVA undergoes hydrogen peroxide-dependent oxidation in the presence of horseradish peroxidase to form a fluorescent dimer that displays excitation/emission maxima of 312/420 nm, respectively. It has been used to quantify hydrogen peroxide production in macrophages and neutrophils.
Chemical Properties
white to beige crystalline powder
Uses
A neuroendocrine tumor marker. Dihydroxyphenylacetic Acid (DOPAC) metabolite.
Uses
Fluorimetric reagent and major catecholamine metaboliteHomovanillic acid is used as a reagent in the determination of oxidative enzymes. It is associated with dopamine levels in the brain. Its presence supports a diagnosis of neuroblastoma and malignant pheochromocytoma.
Definition
ChEBI: A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Biological Activity
Fluorimetric reagent and major catecholamine metabolite. Used for fluorimetric determination of oxidative enzymes including glucose oxidase.
storage
+4°C
Homovanillic acid Preparation Products And Raw materials
Global( 390)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
View Lastest Price from Homovanillic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-10-16 | Chromic sulfate
306-08-1
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-09-06 | Homovanillic acid
306-08-1
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. | |
 |
2023-09-06 | 2-Fluoroethanol
306-08-1
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. |
-
- Chromic sulfate
306-08-1
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- Homovanillic acid
306-08-1
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
-
- 2-Fluoroethanol
306-08-1
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
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