ChemicalBook >> CAS DataBase List >>Tolperisone hydrochloride
Tolperisone hydrochloride
- CAS No.
- 3644-61-9
- Chemical Name:
- Tolperisone hydrochloride
- Synonyms
- Abbsa;n-553;Isocalm;Kineorl;muscalm;Atmosgen;Minacalm;midocalm;mydocalm;Arantoick
- CBNumber:
- CB7200340
- Molecular Formula:
- C16H24ClNO
- Molecular Weight:
- 281.82
- MDL Number:
- MFCD00058211
- MOL File:
- 3644-61-9.mol
- MSDS File:
- SDS
Last updated:2024-04-07 18:44:46
| Melting point | 181-183°C |
|---|---|
| storage temp. | room temp |
| solubility | H2O: >20mg/mL |
| form | solid |
| color | white |
| PH | pH(50g/l, 25℃) : 4.5～5.5 |
| Water Solubility | almost transparency |
| Merck | 14,9522 |
| CAS DataBase Reference | 3644-61-9(CAS DataBase Reference) |
| FDA UNII | 8Z075K2TIG |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332 | |||||||||
| Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 20/21/22-52/53-36/37/38 | |||||||||
| Safety Statements | 26-36-45-61-36/37-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UH1575500 | |||||||||
| Toxicity | LD50 s.c. in mice: 620 mg/kg (Porszasz, 1961) | |||||||||
| NFPA 704 |
|
Tolperisone hydrochloride price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T3577 | Tolperisone hydrochloride ≥98% (HPLC), solid | 3644-61-9 | 50mg | $144 | 2024-03-01 | Buy |
| Sigma-Aldrich | T3577 | Tolperisone hydrochloride ≥98% (HPLC), solid | 3644-61-9 | 250mg | $442 | 2024-03-01 | Buy |
| TCI Chemical | T1319 | Tolperisone Hydrochloride >99.0%(HPLC)(T) | 3644-61-9 | 25g | $75 | 2021-12-16 | Buy |
| Cayman Chemical | 26078 | Tolperisone (hydrochloride) | 3644-61-9 | 1g | $363 | 2024-03-01 | Buy |
| Cayman Chemical | 26078 | Tolperisone (hydrochloride) | 3644-61-9 | 5g | $1085 | 2024-03-01 | Buy |
Tolperisone hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White Solid
Originator
Tolperisone hydrochloride,Shanghai Abochem Chemical Co.
Uses
Tolperisone hydrochloride can be used as a muscle relaxant.
Definition
ChEBI: Tolperisone hydrochloride is an aromatic ketone.
Manufacturing Process
To 1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanol in chloroform was added an excess of thionyl chloride and the reaction mixture refluxed until completed. It was then taken to dryness under reduced pressure and the residue crystallized by dissolving in hot alcohol and diluting with ethyl acetate. An aqueous solution of the obtained N-[3-chloro-3-(p-tolyl)propyl]piperidine hydrochloride was hydrogenated at 3 atmospheres in the presence of buffered palladium-on-charcoal catalyst. 1-Piperidino-2-methyl-3-(p-tolyl)-3-propanone was purified by distilling the base (boiling point 106-107°C/1 mm) and reconverting to the hydrochloride, melting point 216-217°C.
Therapeutic Function
Muscle relaxant, Vasodilator
Biochem/physiol Actions
Tolperisone is derived from piperidine and possesses membrane stabilizing action. It helps in reducing the effect of spasticities associated with the nervous and muscular system. It exhibits muscle relaxant action through attenuating voltage-gated sodium channels in the brain stem.
Tolperisone hydrochloride Preparation Products And Raw materials
Global( 304)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
| Shanghai Affida new material science and technology center | +undefined15081010295 | 2691956269@qq.com | China | 359 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales02@airuikechemical.com | China | 994 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| Hubei XinRunde Chemical Co., Ltd. | +8615102730682 | bruce@xrdchem.cn | CHINA | 566 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
View Lastest Price from Tolperisone hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-07 | Tolperisone hydrochloride
3644-61-9
|
US $100.00 / kg | 1kg | 99% | 1t | Zibo Wei Bin Import & Export Trade Co. Ltd. | |
 |
2024-04-07 | Tolperisone hydrochloride
3644-61-9
|
US $0.00-0.00 / g | 1g | 99.9% | 20tons | airuikechemical co., ltd. | |
 |
2024-03-19 | Tolperisone Hydrochloride
3644-61-9
|
US $0.00-0.00 / KG | 1KG | 99 | 10 tons | Shanghai Affida new material science and technology center |
-
- Tolperisone hydrochloride
3644-61-9
- US $100.00 / kg
- 99%
- Zibo Wei Bin Import & Export Trade Co. Ltd.
-
- Tolperisone hydrochloride
3644-61-9
- US $0.00-0.00 / g
- 99.9%
- airuikechemical co., ltd.
-
- Tolperisone Hydrochloride
3644-61-9
- US $0.00-0.00 / KG
- 99
- Shanghai Affida new material science and technology center
3644-61-9(Tolperisone hydrochloride)Related Search:
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TOLPERISONE HYDROCHLORIDE
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1-Propanone, 2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-, hydrochloride (9CI)
Abbsa
Arantoick
Atmosgen
Besnoline
Isocalm
Kineorl
Menopatol
Metosomin
Minacalm
Naismeritin
Propiophenone, 2,4'-dimethyl-3-piperidino-, hydrochloride (7CI, 8CI)
Tolisartine
2-methyl-1-(4-methylphenyl)-3-piperidin-1-yl-propan-1-one hydrochloride
2-methyl-1-(4-methylphenyl)-3-piperidin-1-ylpropan-1-one hydrochloride
2-Methyl-1-(4-Methylphenyl)-3-(1-piperidinyl)-1-propanone Hydrochloride
1-Propanone, 2-Methyl-1-(4-Methylphenyl)-3-(1-piperidinyl)-, hydrochloride (1:1)
2,4’-dimethyl-3-piperidino-propiophenonhydrochloride
2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanonhydrochloride
2-methyl-3-piperidino-1-p-tolylpropan-1-onehydrochloride
midocalm
muscalm
mydocalm
n-553
Tolperisone hydrochloride, >=99%
Tolperisone Hydrochloridum
Topiperone hydrochloride
Tolperisonce hcl
Tolperisone hydrochloride USP/EP/BP
Tolperisone HCl (AV 650)
Tolperisone HydrochlorideQ: What is
Tolperisone Hydrochloride Q: What is the CAS Number of
Tolperisone Hydrochloride Q: What is the storage condition of
Tolperisone Hydrochloride Q: What are the applications of
Tolperisone Hydrochloride
TIANFU CHEM Tolperisone hydrochloride
Toperidone hydrochloride
Eperisone Impurity 18
Eperisone Impurity 2 HCl
Tolperisone HCl Reference Standard
3644-61-9
3944-61-9
3644-61-8
C16H23NOHCl
C16H23NOHClC16H24ClNO
C16H24NOCl
Intermediates & Fine Chemicals
Pharmaceuticals